Drug discovery for breast cancer and co-instantaneous cardiovascular disease: what is the future?

Tetrahydropyrroloquinolinone Type Dual Inhibitors of Aromatase/Aldosterone Synthase as a Novel Strategy for Breast Cancer Patients with Elevated Cardiovascular Risks

(2013) Lina Yin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer treatment and survivorship statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Novel Imidazol-1-ylmethyl Substituted 1,2,5,6-Tetrahydropyrrolo[3,2,1-ij]quinolin-4-ones as Potent and Selective CYP11B1 Inhibitors for the Treatment of Cushing’s Syndrome

(2012) Lina Yin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective Dual Inhibitors of CYP19 and CYP11B2: Targeting Cardiovascular Diseases Hiding in the Shadow of Breast Cancer

(2012) Qingzhong Hu et al.   JOURNAL OF MEDICINAL CHEMISTRY

3-Pyridyl Substituted Aliphatic Cycles as CYP11B2 Inhibitors: Aromaticity Abolishment of the Core Significantly Increased Selectivity over CYP1A2

(2012) Lina Yin et al.   PLoS One

Synthesis and biological evaluation of imidazolylmethylacridones as cytochrome P-450 enzymes inhibitors

(2012) Ashraf H. Abadi et al.   MedChemComm

Comparison of breast cancer recurrence risk and cardiovascular disease incidence risk among postmenopausal women with breast cancer

(2011) Aditya Bardia et al.   BREAST CANCER RESEARCH AND TREATMENT

Putting the Cardiovascular Safety of Aromatase Inhibitors in Patients with Early Breast Cancer into Perspective

(2011) Muhammad Younus et al.   DRUG SAFETY

Toxicity of Adjuvant Endocrine Therapy in Postmenopausal Breast Cancer Patients: A Systematic Review and Meta-analysis

(2011) Eitan Amir et al.   JNCI-Journal of the National Cancer Institute

Isopropylidene Substitution Increases Activity and Selectivity of Biphenylmethylene 4-Pyridine Type CYP17 Inhibitors

(2010) Qingzhong Hu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Replacement of Imidazolyl by Pyridyl in Biphenylmethylenes Results in Selective CYP17 and Dual CYP17/CYP11B1 Inhibitors for the Treatment of Prostate Cancer

(2010) Qingzhong Hu et al.   JOURNAL OF MEDICINAL CHEMISTRY

The lack of target specificity of small molecule anticancer kinase inhibitors is correlated with their ability to damage myocytes in vitro

(2010) Brian B. Hasinoff et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A woman's heart

(2009) Michael S. Ewer et al.   CANCER

Competing Causes of Death From a Randomized Trial of Extended Adjuvant Endocrine Therapy for Breast Cancer

(2008) J.-A. W. Chapman et al.   JNCI-Journal of the National Cancer Institute