Advances in zebrafish chemical screening technologies

Zebrafish screen identifies novel compound with selective toxicity against leukemia

(2012) S. Ridges et al.   BLOOD

Identification of Modulators of Hair Cell Regeneration in the Zebrafish Lateral Line

(2012) P. Namdaran et al.   JOURNAL OF NEUROSCIENCE

Automated Reporter Quantification In Vivo: High-Throughput Screening Method for Reporter-Based Assays in Zebrafish

(2012) Steven L. Walker et al.   PLoS One

Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination

(2012) Veerander P. S. Ghotra et al.   PLoS One

Development and Validation of an Automated High-Throughput System for Zebrafish In Vivo Screenings

(2012) Ainhoa Letamendia et al.   PLoS One

Automated Phenotype Recognition for Zebrafish Embryo Based In Vivo High Throughput Toxicity Screening of Engineered Nano-Materials

(2012) Rong Liu et al.   PLoS One

Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology

(2012) David Kokel et al.   TRENDS IN BIOTECHNOLOGY

Developmental exposures to ethanol or dimethylsulfoxide at low concentrations alter locomotor activity in larval zebrafish: Implications for behavioral toxicity bioassays

(2011) Te-Hao Chen et al.   AQUATIC TOXICOLOGY

A novel high-throughput imaging system for automated analyses of avoidance behavior in zebrafish larvae

(2011) Sean D. Pelkowski et al.   BEHAVIOURAL BRAIN RESEARCH

Detection of water toxicity using cytochrome P450 transgenic zebrafish as live biosensor: For polychlorinated biphenyls toxicity

(2011) Karen W.Y. Hung et al.   BIOSENSORS & BIOELECTRONICS

A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling

(2011) Manush Saydmohammed et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

The developing zebrafish (Danio rerio): A vertebrate model for high-throughput screening of chemical libraries

(2011) Charles A. Lessman   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

A high-throughput chemically induced inflammation assay in zebrafish

(2011) Claudia A d'Alençon et al.   BMC BIOLOGY

Automated analysis of zebrafish images for phenotypic changes in drug discovery

(2011) Shiye Chen et al.   JOURNAL OF NEUROSCIENCE METHODS

Zebrafish embryo development in a microfluidic flow-through system

(2011) Eric M. Wielhouwer et al.   LAB ON A CHIP

Fully automated cellular-resolution vertebrate screening platform with parallel animal processing

(2011) Tsung-Yao Chang et al.   LAB ON A CHIP

Chemical informatics and target identification in a zebrafish phenotypic screen

(2011) Christian Laggner et al.   Nature Chemical Biology

High-throughput imaging of adult fluorescent zebrafish with an LED fluorescence macroscope

(2011) Jessica S Blackburn et al.   Nature Protocols

Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models

(2011) Thomas C. Farrell et al.   NEUROBIOLOGY OF DISEASE

A High-Throughput Screen for Tuberculosis Progression

(2011) Ralph Carvalho et al.   PLoS One

A New System for the Rapid Collection of Large Numbers of Developmentally Staged Zebrafish Embryos

(2011) Isaac Adatto et al.   PLoS One

Drug screening in a zebrafish model of Duchenne muscular dystrophy

(2011) G. Kawahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation

(2011) M. Rovira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zebrafish developmental screening of the ToxCast™ Phase I chemical library

(2011) S. Padilla et al.   REPRODUCTIVE TOXICOLOGY

Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen

(2010) David S. Peal et al.   CIRCULATION

Circuit Neuroscience in Zebrafish

(2010) Rainer W. Friedrich et al.   CURRENT BIOLOGY

Rosuvastatin, Identified From a Zebrafish Chemical Genetic Screen for Antiangiogenic Compounds, Suppresses the Growth of Prostate Cancer

(2010) Chunyang Wang et al.   EUROPEAN UROLOGY

Rapid behavior-based identification of neuroactive small molecules in the zebrafish

(2010) David Kokel et al.   Nature Chemical Biology

High-throughput in vivo vertebrate screening

(2010) Carlos Pardo-Martin et al.   NATURE METHODS

Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish

(2010) Justin D. Clifton et al.   PLoS One

Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

(2010) J. Rihel et al.   SCIENCE

A Chemical Screen to Identify Novel Inhibitors of Fin Regeneration in Zebrafish

(2010) Douglas Oppedal et al.   Zebrafish

Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line

(2010) Allison B. Coffin et al.   Zebrafish

Simple vertebrate models for chemical genetics and drug discovery screens: Lessons from zebrafish andXenopus

(2009) Grant N. Wheeler et al.   DEVELOPMENTAL DYNAMICS

Automated image-based phenotypic analysis in zebrafish embryos

(2009) Andreas Vogt et al.   DEVELOPMENTAL DYNAMICS

Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages

(2009) Gabriela Molina et al.   Nature Chemical Biology

Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation

(2009) Jing-Ruey J Yeh et al.   Nature Chemical Biology

Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos

(2009) Jochen Gehrig et al.   NATURE METHODS

Chemical genetic screening in the zebrafish embryo

(2009) Charles K Kaufman et al.   Nature Protocols

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

(2009) Y. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zebrafish embryos as models for embryotoxic and teratological effects of chemicals

(2009) Lixin Yang et al.   REPRODUCTIVE TOXICOLOGY

Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish embryo

(2009) Ingrid W.T. Selderslaghs et al.   REPRODUCTIVE TOXICOLOGY

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell

Zebrafish: a predictive model for assessing drug-induced toxicity

(2008) Patricia McGrath et al.   DRUG DISCOVERY TODAY

MPTP and MPP+ target specific aminergic cell populations in larval zebrafish

(2008) V Sallinen et al.   JOURNAL OF NEUROCHEMISTRY

An Automated Method for Cell Detection in Zebrafish

(2008) Tianming Liu et al.   NEUROINFORMATICS

A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development

(2008) Kevin S Jones et al.   Nutrition & Metabolism

Identification of a Novel Retinoid by Small Molecule Screening with Zebrafish Embryos

(2008) Chetana Sachidanandan et al.   PLoS One

Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugs

(2008) Matthew J. Winter et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Identification of Genetic and Chemical Modulators of Zebrafish Mechanosensory Hair Cell Death

(2008) Kelly N. Owens et al.   PLoS Genetics