Epidermal growth factor receptor pathway mutation and expression profiles in cervical squamous cell carcinoma: therapeutic implications

Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs

(2015)   Oncotarget

PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes

(2015) Filip Janku et al.   Oncotarget

KRAS mutations: Analytical considerations

(2014) Marta Herreros-Villanueva et al.   CLINICA CHIMICA ACTA

Human Papillomavirus Type Distribution in Invasive Cervical Cancers From Madhya Pradesh

(2014) Kavita Munjal et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Cox-2, EGFR, and ERBB-2 Expression in Cervical Intraepithelial Neoplasia and Cervical Cancer Using an Automated Imaging System

(2014) Elza M. Fukazawa et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

TP53 and PIK3CA gene mutations in adenocarcinoma, squamous cell carcinoma and high-grade intraepithelial neoplasia of the cervix

(2014) Maria Lina Tornesello et al.   Journal of Translational Medicine

Designing a High-Throughput Somatic Mutation Profiling Panel Specifically for Gynaecological Cancers

(2014) Vivian M. Spaans et al.   PLoS One

PIK3CA Mutations Frequently Coexist with EGFR/KRAS Mutations in Non-Small Cell Lung Cancer and Suggest Poor Prognosis in EGFR/KRAS Wildtype Subgroup

(2014) Lei Wang et al.   PLoS One

AKT Inhibitors Promote Cell Death in Cervical Cancer through Disruption of mTOR Signaling and Glucose Uptake

(2014) Ramachandran Rashmi et al.   PLoS One

Assessing PIK3CA and PTEN in Early-Phase Trials with PI3K/AKT/mTOR Inhibitors

(2014) Filip Janku et al.   Cell Reports

When Overgrowth Bumps Into Cancer: The PTEN-Opathies

(2013) JESSICA MESTER et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Epidermal growth factor receptor targeting in cancer: A review of trends and strategies

(2013) Chetan Yewale et al.   BIOMATERIALS

Oncogenic mutations in cervical cancer

(2013) Alexi A. Wright et al.   CANCER

Target-Based Therapeutic Matching in Early-Phase Clinical Trials in Patients with Advanced Colorectal Cancer and PIK3CA Mutations

(2013) P. Ganesan et al.   MOLECULAR CANCER THERAPEUTICS

Landscape of genomic alterations in cervical carcinomas

(2013) Akinyemi I. Ojesina et al.   NATURE

The quest to overcome resistance to EGFR-targeted therapies in cancer

(2013) Curtis R Chong et al.   NATURE MEDICINE

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

(2013) Jiri Polivka et al.   PHARMACOLOGY & THERAPEUTICS

Discovery of a Novel ERK Inhibitor with Activity in Models of Acquired Resistance to BRAF and MEK Inhibitors

(2013) E. J. Morris et al.   Cancer Discovery

India has world's highest number of cervical cancer deaths

(2013) S. Bhaumik   BMJ-British Medical Journal

The HPV16 E6 Oncoprotein Causes Prolonged Receptor Protein Tyrosine Kinase Signaling and Enhances Internalization of Phosphorylated Receptor Species

(2013) Jennifer M. Spangle et al.   PLoS Pathogens

Regulation of the transcriptional activity of nuclear receptors by the MEK/ERK1/2 pathway

(2012) Fabien Zassadowski et al.   CELLULAR SIGNALLING

Targeting the EGFR signaling pathway in cancer therapy

(2012) Parthasarathy Seshacharyulu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

PIK3CA mutational status and overall survival in patients with cervical cancer treated with radical chemoradiotherapy

(2012) John B. McIntyre et al.   GYNECOLOGIC ONCOLOGY

Epidermal growth factor receptor as a biomarker for cervical cancer

(2011) T. Soonthornthum et al.   ANNALS OF ONCOLOGY

EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target

(2011) K Iida et al.   BRITISH JOURNAL OF CANCER

Sarcomatoid renal cell carcinoma is an example of epithelial-mesenchymal transition

(2011) J. L. Conant et al.   JOURNAL OF CLINICAL PATHOLOGY

PIK3CA Mutations in Patients with Advanced Cancers Treated with PI3K/AKT/mTOR Axis Inhibitors

(2011) F. Janku et al.   MOLECULAR CANCER THERAPEUTICS

Allelic Loss of 10q23.3, the PTEN Gene Locus in Cervical Carcinoma from Northern Indian Population

(2011) M. Moshahid Alam Rizvi et al.   PATHOLOGY & ONCOLOGY RESEARCH

PIK3CA Mutations Frequently Coexist with RAS and BRAF Mutations in Patients with Advanced Cancers

(2011) Filip Janku et al.   PLoS One

The frequency of KRAS mutation detection in human colon carcinoma is influenced by the sensitivity of assay methodology: A comparison between direct sequencing and real-time PCR

(2010) Takashi Kobunai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The epidermal growth factor receptor pathway in relation to pelvic lymph node metastasis and survival in early-stage cervical cancer

(2010) Jasper J.H. Eijsink et al.   HUMAN PATHOLOGY

Cervical cancer in Indian rural women: Trends over two decades

(2010) S. Chhabra et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

(2010) Wendy De Roock et al.   LANCET ONCOLOGY

PIK3CA Mutations in Colorectal Cancer Are Associated with Clinical Resistance to EGFR-Targeted Monoclonal Antibodies

(2009) A. Sartore-Bianchi et al.   CANCER RESEARCH

PIK3CA Mutations Are Not a Major Determinant of Resistance to the Epidermal Growth Factor Receptor Inhibitor Cetuximab in Metastatic Colorectal Cancer

(2009) H. Prenen et al.   CLINICAL CANCER RESEARCH

Anti-Egfr Therapy in Colorectal Cancer: How to Choose The Right Patient

(2009) F. Meriggi et al.   CURRENT DRUG TARGETS

A Robust Automated Measure of Average Antibody Staining in Immunohistochemistry Images

(2009) Kingshuk Roy Choudhury et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

PIK3CA gene mutations and amplifications in uterine cancers, identified by methods that avoid confounding by PIK3CA pseudogene sequences

(2008) Takahito Miyake et al.   CANCER LETTERS

Absence of epidermal growth factor receptor mutations in cervical cancer

(2007) H. ARIAS-PULIDO et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER