Anoikis-resistant subpopulations of human osteosarcoma display significant chemoresistance and are sensitive to targeted epigenetic therapies predicted by expression profiling

Sox5 induces epithelial to mesenchymal transition by transactivation of Twist1

(2014) Xin-Hong Pei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma

(2014) S H Lee et al.   BRITISH JOURNAL OF CANCER

Decoding the Knots of Initiation of Oncogenic Epithelial-Mesenchymal Transition in Tumor Progression

(2014) Pengda Guo et al.   CURRENT CANCER DRUG TARGETS

Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity

(2014) Toshinori Ozaki et al.   FEBS Journal

5-Azacytidine suppresses the proliferation of pancreatic cancer cells by inhibiting the Wnt/β-catenin signaling pathway

(2014) H. Zhang et al.   GENETICS AND MOLECULAR RESEARCH

Pleiotropic antitumor effects of the pan-HDAC inhibitor ITF2357 against c-Myc-overexpressing human B-cell non-Hodgkin lymphomas

(2014) Roberta Zappasodi et al.   INTERNATIONAL JOURNAL OF CANCER

Oct4 Mediates Tumor Initiating Properties in Oral Squamous Cell Carcinomas through the Regulation of Epithelial-Mesenchymal Transition

(2014) Lo-Lin Tsai et al.   PLoS One

Down Regulation of Wnt Signaling Mitigates Hypoxia-Induced Chemoresistance in Human Osteosarcoma Cells

(2014) Donald J. Scholten et al.   PLoS One

Rewriting the Epigenetic Code for Tumor Resensitization: A Review

(2014) Bryan Oronsky et al.   Translational Oncology

Inhibition of the Wnt-β-catenin and Notch signaling pathways sensitizes osteosarcoma cells to chemotherapy

(2013) Yimin Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell cycle arrest or survival signaling through αv integrins, activation of PKC and ERK1/2 lead to anoikis resistance of ovarian cancer spheroids

(2013) Ludovic Carduner et al.   EXPERIMENTAL CELL RESEARCH

Runt-related transcription factor 2 (RUNX2) inhibits p53-dependent apoptosis through the collaboration with HDAC6 in response to DNA damage

(2013) T Ozaki et al.   Cell Death & Disease

Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line

(2012) Sara R Martins-Neves et al.   BMC CANCER

The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines

(2012) Claudia M.J. Lucero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

c-Myc Overexpression Promotes Osteosarcoma Cell Invasion Via Activation of MEK-ERK Pathway

(2012) Gang Han et al.   ONCOLOGY RESEARCH

Combinatorial Treatment of DNA and Chromatin-Modifying Drugs Cause Cell Death in Human and Canine Osteosarcoma Cell Lines

(2012) Venugopal Thayanithy et al.   PLoS One

Transforming Growth Factor β1 Signal is Crucial for Dedifferentiation of Cancer Cells to Cancer Stem Cells in Osteosarcoma

(2012) Haixia Zhang et al.   STEM CELLS

Salinomycin inhibits osteosarcoma by targeting its tumor stem cells

(2011) Qing-Lian Tang et al.   CANCER LETTERS

Epidermal Growth Factor Receptor (EGFR)-mediated Positive Feedback of Protein-tyrosine Phosphatase ϵ (PTPϵ) on ERK1/2 and AKT Protein Pathways Is Required for Survival of Human Breast Cancer Cells

(2011) Caroline E. Nunes-Xavier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Downregulation of connective tissue growth factor inhibits the growth and invasion of gastric cancer cells and attenuates peritoneal dissemination

(2011) Cheng-Gang Jiang et al.   Molecular Cancer

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

(2011) U Basu-Roy et al.   ONCOGENE

Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family

(2011) S. H. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

c-MYC Suppresses BIN1 to Release Poly(ADP-Ribose) Polymerase 1: A Mechanism by Which Cancer Cells Acquire Cisplatin Resistance

(2011) S. Pyndiah et al.   Science Signaling

Wnt Inhibitory Factor 1 Decreases Tumorigenesis and Metastasis in Osteosarcoma

(2010) E. M. Rubin et al.   MOLECULAR CANCER THERAPEUTICS

Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

(2010) G M Marshall et al.   ONCOGENE

c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis

(2010) T Shimizu et al.   ONCOGENE

Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival

(2009) C A Barton et al.   BRITISH JOURNAL OF CANCER

Cyclin D1 promotes anchorage-independent cell survival by inhibiting FOXO-mediated anoikis

(2009) L Gan et al.   CELL DEATH AND DIFFERENTIATION

Anchorage-independent cell growth signature identifies tumors with metastatic potential

(2009) S Mori et al.   ONCOGENE

Anoikis: A necessary death program for anchorage-dependent cells

(2008) Paola Chiarugi et al.   BIOCHEMICAL PHARMACOLOGY

Anoikis resistance and tumor metastasis

(2008) Craig D. Simpson et al.   CANCER LETTERS

Myc-Mediated Transcriptional Repression by Recruitment of Histone Deacetylase

(2008) J. F. Kurland et al.   CANCER RESEARCH