Actions of thrombin in the interstitium

Apoptotic primary normal human dermal fibroblasts for in vitro models of fibrosis

(2015) Elena García-Gareta et al.   ANALYTICAL BIOCHEMISTRY

Proof-of-concept Studies for siRNA-mediated Gene Silencing for Coagulation Factors in Rat and Rabbit

(2015) Zhu Chen et al.   Molecular Therapy-Nucleic Acids

Neutrophil Extracellular Traps Promote Thrombin Generation Through Platelet-Dependent and Platelet-Independent Mechanisms

(2014) Travis J. Gould et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thrombin Increases Lung Fibroblast Survival while Promoting Alveolar Epithelial Cell Apoptosis via the Endoplasmic Reticulum Stress Marker, CCAAT Enhancer–Binding Homologous Protein

(2013) Ilia Atanelishvili et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Role of hepsin in factor VII activation in zebrafish

(2013) Gauri Khandekar et al.   BLOOD CELLS MOLECULES AND DISEASES

Minimal Differentiation of Classical Monocytes as They Survey Steady-State Tissues and Transport Antigen to Lymph Nodes

(2013) Claudia Jakubzick et al.   IMMUNITY

Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma

(2013) Dusten Unruh et al.   INTERNATIONAL JOURNAL OF CANCER

Protease-Activated Receptor 1 Inhibition by SCH79797 Attenuates Left Ventricular Remodeling and Profibrotic Activities of Cardiac Fibroblasts

(2013) Dmitry L. Sonin et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

An Immunohistochemical Analysis of Tissue Thrombin Expression in the Human Atria

(2013) Keiichi Ito et al.   PLoS One

Role of IGF-1 pathway in lung fibroblast activation

(2013) Chi F Hung et al.   RESPIRATORY RESEARCH

Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells – potential role in lung fibrosis

(2013) Miroslava Didiasova et al.   THROMBOSIS AND HAEMOSTASIS

A Placebo-Controlled Randomized Trial of Warfarin in Idiopathic Pulmonary Fibrosis

(2012) Imre Noth et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Leukocyte-Derived Microparticles in Vascular Homeostasis

(2012) Anne Angelillo-Scherrer   CIRCULATION RESEARCH

Defining the cellular repertoire of GPCRs identifies a profibrotic role for the most highly expressed receptor, protease-activated receptor 1, in cardiac fibroblasts

(2012) Aaron N. Snead et al.   FASEB JOURNAL

PAR-1-dependent and PAR-independent pro-inflammatory signaling in human lung fibroblasts exposed to thrombin

(2012) Alejandro Ortiz-Stern et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Downregulation of FGL2/prothrombinase delays HCCLM6 xenograft tumour growth and decreases tumour angiogenesis

(2012) Yanling Liu et al.   LIVER INTERNATIONAL

Effects of MASP-1 of the Complement System on Activation of Coagulation Factors and Plasma Clot Formation

(2012) Katharina Hess et al.   PLoS One

Antiinflammatory and antifibrotic effects of the oral direct thrombin inhibitor dabigatran etexilate in a murine model of interstitial lung disease

(2011) Galina S. Bogatkevich et al.   ARTHRITIS AND RHEUMATISM

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

(2011) F. Semeraro et al.   BLOOD

Hypercoagulability in cirrhosis: causes and consequences1

(2011) A. TRIPODI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The prothrombinase activity of FGL2 contributes to the pathogenesis of experimental arthritis

(2011) MC Melnyk et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

The role of hypercoagulability in liver fibrogenesis

(2011) Quentin M. Anstee et al.   Clinics and Research in Hepatology and Gastroenterology

Characterization of Differences between Blood Sample Matrices in Untargeted Metabolomics

(2010) Judith R. Denery et al.   ANALYTICAL CHEMISTRY

Interstitial Plasmin Activity With Epsilon Aminocaproic Acid: Temporal and Regional Heterogeneity

(2010) Daryl L. Reust et al.   ANNALS OF THORACIC SURGERY

Heparin Cofactor II Protects Against Angiotensin II-Induced Cardiac Remodeling Via Attenuation of Oxidative Stress in Mice

(2010) Yuka Sumitomo-Ueda et al.   HYPERTENSION

Binding of Anti-GRP78 Autoantibodies to Cell Surface GRP78 Increases Tissue Factor Procoagulant Activity via the Release of Calcium from Endoplasmic Reticulum Stores

(2010) Ali A. Al-Hashimi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombin-dependent MMP-2 Activity Is Regulated by Heparan Sulfate

(2010) Bon-Hun Koo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shedding of microparticles by myofibroblasts as mediator of cellular cross-talk during normal wound healing

(2010) Véronique J. Moulin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Advances in Proximal Fluid Proteomics for Disease Biomarker Discovery

(2010) Pang-ning Teng et al.   JOURNAL OF PROTEOME RESEARCH

rFVIIa transported from the blood stream into tissues is functionally active

(2010) R. GOPALAKRISHNAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments

(2010) Matthias Jacob et al.   JOURNAL OF VASCULAR RESEARCH

Anti-thrombin Therapy During Warm Ischemia and Cold Preservation Prevents Chronic Kidney Graft Fibrosis in a DCD Model

(2009) F. Favreau et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Quantification of C-Reactive protein in human blood plasma using near-infrared Raman spectroscopy

(2009) M. S. Bergholt et al.   ANALYST

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot

(2009) Krishana C. Gulla et al.   IMMUNOLOGY

Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain

(2008) E. S. Mullins et al.   BLOOD

The Role of the Extracellular Matrix in Tissue Distribution of Macromolecules in Normal and Pathological Tissues: Potential Therapeutic Consequences

(2008) Helge Wiig et al.   MICROCIRCULATION

The Role of Natural Anticoagulants in the Pathogenesis and Management of Systemic Activation of Coagulation and Inflammation in Critically Ill Patients

(2008) Marcel Levi et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS