Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β

PDK1 regulates platelet activation and arterial thrombosis

(2013) X. Chen et al.   BLOOD

PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses

(2013) Carol Dangelmaier et al.   THROMBOSIS AND HAEMOSTASIS

Dual Regulation of Glycogen Synthase Kinase 3 (GSK3)α/β by Protein Kinase C (PKC)α and Akt Promotes Thrombin-mediated Integrin αIIbβ3Activation and Granule Secretion in Platelets

(2012) Samantha F. Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical Role for an Acidic Amino Acid Region in Platelet Signaling by the HemITAM (Hemi-immunoreceptor Tyrosine-based Activation Motif) Containing Receptor CLEC-2 (C-type Lectin Receptor-2)

(2012) Craig E. Hughes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Podoplanin: emerging functions in development, the immune system, and cancer

(2012) Jillian L. Astarita et al.   Frontiers in Immunology

An important role for Akt3 in platelet activation and thrombosis

(2011) K. A. O'Brien et al.   BLOOD

mTORC2 Protein-mediated Protein Kinase B (Akt) Serine 473 Phosphorylation Is Not Required for Akt1 Activity in Human Platelets

(2011) Samantha F. Moore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac

(2010) A. Y. Pollitt et al.   BLOOD

CLEC-2 activates Syk through dimerization

(2010) C. E. Hughes et al.   BLOOD

Syk-dependent Phosphorylation of CLEC-2

(2010) Sonia Séverin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GPVI and CLEC-2 in hemostasis and vascular integrity

(2010) S. P. WATSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Endoplasmic Reticulum Stress in Diabetic Hearts Abolishes Erythropoietin-Induced Myocardial Protection by Impairment of Phospho–Glycogen Synthase Kinase-3β–Mediated Suppression of Mitochondrial Permeability Transition

(2009) Takayuki Miki et al.   DIABETES

Non-redundant Roles of Phosphoinositide 3-Kinase Isoforms α and β in Glycoprotein VI-induced Platelet Signaling and Thrombus Formation

(2009) Karen Gilio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Phosphoinositide 3-Kinase β in Glycoprotein VI-mediated Akt Activation in Platelets

(2009) Soochong Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CLEC-2 Is a Phagocytic Activation Receptor Expressed on Murine Peripheral Blood Neutrophils

(2009) A. M. Kerrigan et al.   JOURNAL OF IMMUNOLOGY

GSK3  is a negative regulator of platelet function and thrombosis

(2008) D. Li et al.   BLOOD

Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway

(2008) P. Flevaris et al.   BLOOD

Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2

(2008) C. E. HUGHES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS