The impact of antiretroviral therapy on population-level virulence evolution of HIV-1

How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?

(2015) Jintanat Ananworanich et al.   Current Opinion in HIV and AIDS

Reassessment of HIV-1 Acute Phase Infectivity: Accounting for Heterogeneity and Study Design with Simulated Cohorts

(2015) Steve E. Bellan et al.   PLOS MEDICINE

Perinatally acquired HIV infection in adolescents from sub-Saharan Africa: a review of emerging challenges

(2014) Elizabeth D Lowenthal et al.   LANCET INFECTIOUS DISEASES

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

(2014) Rebecca Payne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The early spread and epidemic ignition of HIV-1 in human populations

(2014) N. R. Faria et al.   SCIENCE

Virulence and Pathogenesis of HIV-1 Infection: An Evolutionary Perspective

(2014) C. Fraser et al.   SCIENCE

Immuno-epidemiological Modeling of HIV-1 Predicts High Heritability of the Set-Point Virus Load, while Selection for CTL Escape Dominates Virulence Evolution

(2014) Christiaan H. van Dorp et al.   PLoS Computational Biology

An HIV Epidemic Model Based on Viral Load Dynamics: Value in Assessing Empirical Trends in HIV Virulence and Community Viral Load

(2014) Joshua T. Herbeck et al.   PLoS Computational Biology

The Contribution of Viral Genotype to Plasma Viral Set-Point in HIV Infection

(2014) Emma Hodcroft et al.   PLoS Pathogens

Temporal trends in prognostic markers of HIV-1 virulence and transmissibility: an observational cohort study

(2014) Nikos Pantazis et al.   Lancet HIV

No change in viral set point or CD4 cell decline among antiretroviral treatment-naïve, HIV-1-infected individuals enrolled in the Danish HIV Cohort Study in 1995-2010

(2013) M Helleberg et al.   HIV MEDICINE

Virus-induced target cell activation reconciles set-point viral load heritability and within-host evolution

(2013) Anna Hool et al.   Epidemics

Is the virulence of HIV changing? A meta-analysis of trends in prognostic markers of HIV disease progression and transmission

(2011) Joshua T. Herbeck et al.   AIDS

Modelling the Impact of Antiretroviral Therapy on the Epidemic of HIV

(2011) Brian G. Williams et al.   CURRENT HIV RESEARCH

Prevention of HIV-1 Infection with Early Antiretroviral Therapy

(2011) Myron S. Cohen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Strong Case for Viral Genetic Factors in HIV Virulence

(2011) Viktor Müller et al.   Viruses-Basel

Estimating the impact of antiretroviral therapy: regional and global estimates of life-years gained among adults

(2010) M. Mahy et al.   SEXUALLY TRANSMITTED INFECTIONS

No evidence of a change in HIV-1 virulence since 1996 in France

(2009) Pénélope Troude et al.   AIDS

Is HIV Becoming More Virulent? Initial CD4 Cell Counts among HIV Seroconverters during the Course of the HIV Epidemic: 1985–2007

(2009) Nancy Crum‐Cianflone et al.   CLINICAL INFECTIOUS DISEASES

Trends in Post-Infection CD4 Cell Counts and Plasma HIV-1 RNA Levels in HIV-1-Infected Patients in France Between 1997 and 2005

(2009) Valérie Potard et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Viral Load Levels Measured at Set-Point Have Risen Over the Last Decade of the HIV Epidemic in the Netherlands

(2009) Luuk Gras et al.   PLoS One

Increasing Clinical Virulence in Two Decades of the Italian HIV Epidemic

(2009) Viktor Müller et al.   PLoS Pathogens

Virulence evolution and the trade-off hypothesis: history, current state of affairs and the future

(2008) S. ALIZON et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Lack of Evidence for Changing Virulence of HIV-1 in North America

(2008) Joshua T. Herbeck et al.   PLoS One