Multiple roles of Nrf2-Keap1 signaling

Nrf2 regulates haematopoietic stem cell function

(2013) Jennifer J. Tsai et al.   NATURE CELL BIOLOGY

Regulation of Drosophila Metamorphosis by Xenobiotic Response Regulators

(2013) Huai Deng et al.   PLoS Genetics

An overview of transcriptional regulation in response to toxicological insult

(2012) Paul Jennings et al.   ARCHIVES OF TOXICOLOGY

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome

(2012) P. Xue et al.   DIABETES

Nrf2 Protein Up-regulates Antiapoptotic Protein Bcl-2 and Prevents Cellular Apoptosis

(2012) Suryakant K. Niture et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha

(2012) B. N. Chorley et al.   NUCLEIC ACIDS RESEARCH

Imaginal Discs Secrete Insulin-Like Peptide 8 to Mediate Plasticity of Growth and Maturation

(2012) A. Garelli et al.   SCIENCE

Secreted Peptide Dilp8 Coordinates Drosophila Tissue Growth with Developmental Timing

(2012) J. Colombani et al.   SCIENCE

Effects of Oxygen on Growth and Size: Synthesis of Molecular, Organismal, and Evolutionary Studies with Drosophila melanogaster

(2011) Jon F. Harrison et al.   Annual Review of Physiology

Nrf2: control of sensitivity to carcinogens

(2011) Stephen L. Slocum et al.   ARCHIVES OF TOXICOLOGY

The Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cells

(2011) Irene Bobilev et al.   CANCER BIOLOGY & THERAPY

Transcriptional regulation of xenobiotic detoxification in Drosophila

(2011) J. R. Misra et al.   GENES & DEVELOPMENT

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Redox-regulating role of insulin: The essence of insulin effect

(2011) Xin Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism

(2010) Jiansheng Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Steroid hormone receptors in cancer development: A target for cancer therapeutics

(2010) Nihal Ahmad et al.   CANCER LETTERS

Global Downstream Pathway Analysis Reveals a Dependence of Oncogenic NF-E2-Related Factor 2 Mutation on the mTOR Growth Signaling Pathway

(2010) T. Shibata et al.   CANCER RESEARCH

Retinoids Regulate a Developmental Checkpoint for Tissue Regeneration in Drosophila

(2010) Adrian Halme et al.   CURRENT BIOLOGY

Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity

(2010) Jingbo Pi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver

(2010) Neil R. Kitteringham et al.   Journal of Proteomics

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease

(2010) G. P. Sykiotis et al.   Science Signaling

Molecular Targets of Dietary Phenethyl Isothiocyanate and Sulforaphane for Cancer Chemoprevention

(2009) Ka Lung Cheung et al.   AAPS Journal

Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer

(2009) S. Homma et al.   CLINICAL CANCER RESEARCH

Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response

(2009) Zheng Sun et al.   PLoS One

The Insect Neuropeptide PTTH Activates Receptor Tyrosine Kinase Torso to Initiate Metamorphosis

(2009) K. F. Rewitz et al.   SCIENCE

The TOR Pathway Couples Nutrition and Developmental Timing in Drosophila

(2008) Sophie Layalle et al.   DEVELOPMENTAL CELL

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

(2008) Gerasimos P. Sykiotis et al.   DEVELOPMENTAL CELL

Drosophila is an inclusive model for human diseases, growth and development

(2008) Lawrence I. Gilbert   MOLECULAR AND CELLULAR ENDOCRINOLOGY