Article
Obstetrics & Gynecology
L. O. Kettner, N. B. Matthiesen, C. H. Ramlau-Hansen, U. S. Kesmodel, T. B. Henriksen
Summary: The study suggests that fertility treatment with clomiphene citrate may be associated with a small increased risk of childhood idiopathic generalized epilepsy and focal epilepsy.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Kolbe L. Hancock, Nigel Pereira, Paul J. Christos, Allison C. Petrini, Jennifer Hughes, Pak H. Chung, Zev Rosenwaks
Summary: The study aimed to identify the optimal lead follicle size for hCG trigger in Clomiphene Citrate (CC)-intrauterine insemination (IUI) cycles. Results showed that hCG administration at a lead follicle size of 21.1-22.0 mm was associated with higher odds of clinical pregnancy in patients undergoing their first CC-IUI cycles.
FERTILITY AND STERILITY
(2021)
Review
Obstetrics & Gynecology
J. A. Wessel, N. A. Danhof, R. van Eekelen, M. P. Diamond, R. S. Legro, K. Peeraer, T. M. D'Hooghe, M. Erdem, T. Dankert, B. J. Cohlen, C. Thyagaraju, B. W. J. Mol, M. Showell, M. van Wely, M. H. Mochtar, R. Wang
Summary: This study conducted an individual participant data meta-analysis to compare the effectiveness and safety of gonadotrophins, letrozole, and clomiphene citrate in ovarian stimulation with intrauterine insemination (IUI-OS) for couples with unexplained infertility, and explored treatment-covariate interactions for important baseline characteristics in couples undergoing IUI.
HUMAN REPRODUCTION UPDATE
(2022)
Article
Obstetrics & Gynecology
Yu-Han Chiu, Jennifer J. Yland, Paolo Rinaudo, John Hsu, Sean McGrath, Sonia Hernandez-Diaz, Miguel A. Hernan
Summary: This study compared the effectiveness and safety of one cycle of assisted reproductive technology (ART) with three cycles of intrauterine insemination (IUI). The results showed that one cycle of ART had a similar probability of live birth as three cycles of IUI, but slightly higher risks of multiple gestations, preterm births, and neonatal intensive care unit (NICU) admissions.
FERTILITY AND STERILITY
(2022)
Review
Medicine, General & Internal
Jessica Marinaro, Marc Goldstein
Summary: Male factor is significant in a couple's reproductive success, and advances in reproductive technology have overcome traditional barriers to male fertility. Collaborative work between reproductive endocrinologists and reproductive urologists is essential for optimizing fertility outcomes, improving men's health, and providing cost-effective care.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Anca Huniadi, Erika Bimbo-Szuhai, Mihai Botea, Ioana Zaha, Corina Beiusanu, Annamaria Pallag, Liana Stefan, Alin Bodog, Mircea Sandor, Carmen Grierosu
Summary: In a retrospective study, variables associated with successful intrauterine insemination (IUI) and the probability of pregnancy were identified. This information is useful in determining the chances of pregnancy through IUI for couples.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Obstetrics & Gynecology
Meaghan Jain, Andrea Peterson, Nadia Nguyen, Michelle Goldsammler
Summary: This study aimed to evaluate if language preference affects intrauterine insemination outcomes. The results showed that patients with limited English proficiency had a longer duration of infertility before seeking care and a lower cumulative pregnancy rate at the time of final intrauterine insemination, compared to English-proficient patients. Limited English proficiency patients were also more likely to discontinue care after unsuccessful intrauterine insemination.
FERTILITY AND STERILITY
(2023)
Article
Pharmacology & Pharmacy
Ahmed M. Taiyeb, Azheen Haji, Zaid O. Ibraheem, Ghada S. Alsakkal
Summary: The study compared pregnancy outcomes among infertile couples using Clomiphene citrate, Letrozole, and Cetrorelix acetate, finding that patients stimulated with Letrozole had higher clinical pregnancy rates and lower subclinical abortion rates compared to those stimulated with Clomiphene citrate or Cetrorelix acetate.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
(2021)
Article
Obstetrics & Gynecology
Maryam Asgharnia, Marzieh Mehrafza, Azadeh Raoufi, Tahereh Zare Yousefi, Elmira Hosseinzadeh, Sajedeh Samadnia, Ziba Zahiri, Amirhossein Tamimi, Ahmad Hosseini
Summary: This multicenter study found that combination therapy with letrozole and clomiphene citrate was more effective than using either drug alone in patients undergoing ovarian induction plus intrauterine insemination, leading to higher rates of pregnancy success.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Obstetrics & Gynecology
Vivienne Moore, Alice Rumbold, Renae Fernandez, Heather McElroy, Lynette Moore, Lynne Giles, Luke Grzeskowiak, Elizabeth Roughead, Michael Stark, Michael Davies
Summary: A study in South Australia found that 1.6% of pregnancies of at least 20 weeks' gestation were conceived with the use of clomiphene citrate (CC), with 5.7% resulting in multiple births. This increases the proportion of women who achieved an ongoing pregnancy with medical assistance from 4.4% to 6%.
FERTILITY AND STERILITY
(2022)
Article
Obstetrics & Gynecology
Seyma Osmanlioglu, Yavuz Emre Sukur, Vehbi Yavuz Tokgoz, Batuhan Ozmen, Murat Sonmezer, Bulent Berker, Rusen Aytac, Cem Somer Atabekoglu
Summary: Up to three cycles of IUI with ovarian stimulation can be an effective treatment modality in unexplained infertility, with significant clinical pregnancy and live birth rates. The duration of infertility was found to be shorter in women who successfully underwent IUI attempts.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Paversan Archary, Liezel Potgieter, Eman Elgindy, Rudolph Kantum Adageba, Justin Mboloko, Faye Iketubosin, Gamal Serour, Silke Dyer
Summary: This study investigates the utilization, practices, and outcomes of assisted reproductive technology (ART) in Africa in 2018 and 2019. The results show an increasing trend in the utilization of ART, with a high rate of multiple pregnancies, highlighting the need for improved follow-up of ART pregnancies.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Obstetrics & Gynecology
Akhil Muthigi, Samad Jahandideh, Lauren A. Bishop, Firoozeh K. Naeemi, Sharon K. Shipley, Jeanne E. O'Brien, Paul R. Shin, Kate Devine, Cigdem Tanrikut
Summary: This study analyzed 92,471 insemination cycles from a large fertility clinic to examine the relationship between postwash total motile sperm count and IUI outcomes. It was found that a TMSC of >= 9 x 10(6) optimized pregnancy rates, with a gradual decline in success below this threshold. The data can be used for personalized counseling and clinical decision making.
FERTILITY AND STERILITY
(2021)
Review
Biochemistry & Molecular Biology
Mustapha Benkhalifa, Fabien Joao, Cynthia Duval, Debbie Montjean, Molka Bouricha, Rosalie Cabry, Marie-Claire Belanger, Hatem Bahri, Pierre Miron, Moncef Benkhalifa
Summary: After more than four decades of assisted reproductive technology (ART) practice, the failure of in vitro fertilization (IVF) treatments and recurrent implantation failures (RIFs) and repeated pregnancy loss (RPL) remain significant issues. This article reviews different therapeutic options and suggests that immunomodulation and predictive biomarkers may be promising solutions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Obstetrics & Gynecology
Ying Liang, Qing Guo, Xiao-Hua Wu, Li-Nan Zhang, Jun Ge, Mei-Ling Xu, Zheng-Li Feng, Xiao-Qian Wu
Summary: Adding CC/LE to IVF ovulation induction has certain efficacy in terms of low cost and low OHSS incidence. CC/LE deserves more recommendations as a responsible strategy in high responders for advantageous pregnancy outcomes, while the strategy needs to be considered with more comprehensive factors in normal responders.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Thomas L. Toth, Malinda S. Lee, Kristin A. Bendikson, Richard H. Reindollar
FERTILITY AND STERILITY
(2017)
Article
Obstetrics & Gynecology
FERTILITY AND STERILITY
(2017)
Article
Obstetrics & Gynecology
Denis A. Vaughan, Angela Leung, Nina Resetkova, Robin Ruthazer, Alan S. Penzias, Denny Sakkas, Michael M. Alper
FERTILITY AND STERILITY
(2017)
Article
Obstetrics & Gynecology
FERTILITY AND STERILITY
(2017)
Article
Obstetrics & Gynecology
Alan Penzias, Kristin Bendikson, Samantha Butts, Christos Coutifaris, Tommaso Falcone, Gregory Fossum, Susan Gitlin, Clarisa Gracia, Karl Hansen, Jennifer Mersereau, Randall Odem, Robert Rebar, Richard Reindollar, Mitchell Rosen, Jay Sandlow, Michael Vernon
FERTILITY AND STERILITY
(2017)
Article
Obstetrics & Gynecology
Emily C. Holden, Laura E. Dodge, Rita Sneeringer, Vasiliki A. Moragianni, Alan S. Penzias, Michele R. Hacker
Article
Obstetrics & Gynecology
Kathleen Hwang, James F. Smith, R. Matthew Coward, Alan Penzias
FERTILITY AND STERILITY
(2018)
Article
Obstetrics & Gynecology
FERTILITY AND STERILITY
(2018)
Article
Obstetrics & Gynecology
Alan Penzias, Kristin Bendikson, Samantha Butts, Christos Coutifaris, Tommaso Falcone, Susan Gitlin, Clarisa Gracia, Karl Hansen, Sangita Jindal, Jennifer Mersereau, Randall Odem, Robert Rebar, Richard Reindollar, Mitchell Rosen, Jay Sandlow, Peter Schlegel, Dale Stovall, Michael Vernon
FERTILITY AND STERILITY
(2018)
Article
Obstetrics & Gynecology
Alan Penzias, Kristin Bendikson, Samantha Butts, Christos Coutifaris, Tommaso Falcone, Susan Gitlin, Clarisa Gracia, Karl Hansen, Sangita Jindal, Suleena Kalra, Jennifer Mersereau, Randall Odem, Richard Paulson, Samantha Pfeifer, Margareta Pisarska, Robert Rebar, Richard Reindollar, Mitchell Rosen, Jay Sandlow, Peter Schlegel, Dale Stovall, Michael Vernon
FERTILITY AND STERILITY
(2018)
Article
Obstetrics & Gynecology
Anna M. Modest, Lauren A. Wise, Matthew P. Fox, Jennifer Weuve, Alan S. Penzias, Michele R. Hacker
HUMAN REPRODUCTION
(2018)
Article
Genetics & Heredity
Kristi Maas, Sheyla Mirabal, Alan Penzias, Paul M. Sweetnam, Kevin C. Eggan, Denny Sakkas
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2018)
Article
Obstetrics & Gynecology
FERTILITY AND STERILITY
(2018)
Article
Obstetrics & Gynecology
FERTILITY AND STERILITY
(2018)
Article
Obstetrics & Gynecology
Lauren A. Murphy, Emily A. Seidler, Denis A. Vaughan, Nina Resetkova, Alan S. Penzias, Thomas L. Toth, Kim L. Thornton, Denny Sakkas
HUMAN REPRODUCTION
(2019)