Mitochondria in ageing: there is metabolism beyond the ROS

Autophagy mediates pharmacological lifespan extension by spermidineand resveratrol

(2016) Eugenia Morselli et al.   Aging-US

Surviving in the cold: yeast mutants with extended hibernating lifespan are oxidant sensitive

(2016) Lucie Postma et al.   Aging-US

A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging

(2016) Bernd Timmermann et al.   Aging-US

Polyamines in aging and disease

(2016) Nadège Minois et al.   Aging-US

Molecular mechanisms underlying genotype-dependent responses to dietary restriction

(2013) Jennifer Schleit et al.   AGING CELL

Mitochondrial fission facilitates mitophagy inSaccharomyces cerevisiae

(2013) Kai Mao et al.   Autophagy

Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation

(2013) Sunil Laxman et al.   CELL

Tpo1-mediated spermine and spermidine export controls cell cycle delay and times antioxidant protein expression during the oxidative stress response

(2013) Antje Krüger et al.   EMBO REPORTS

Loss of iron triggers PINK1/Parkin-independent mitophagy

(2013) George F G Allen et al.   EMBO REPORTS

The role of mitochondria in aging

(2013) Ana Bratic et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolite proofreading, a neglected aspect of intermediary metabolism

(2013) Emile Van Schaftingen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Metabolite damage and its repair or pre-emption

(2013) Carole L Linster et al.   Nature Chemical Biology

Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner

(2013) Varun K Gupta et al.   NATURE NEUROSCIENCE

Time line of redox events in aging postmitotic cells

(2013) Nicolas Brandes et al.   eLife

Eat-Me: Autophagy, Phagocytosis, and Reactive Oxygen Species Signaling

(2012) Philip J. Vernon et al.   ANTIOXIDANTS & REDOX SIGNALING

Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice

(2012) Kati J. Ahlqvist et al.   Cell Metabolism

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

(2012) Antero Salminen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Coming into View: Eukaryotic Iron Chaperones and Intracellular Iron Delivery: FIGURE 1.

(2012) Caroline C. Philpott   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy

(2012) Noriko Kondo-Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism

(2012) J. M. Buescher et al.   SCIENCE

Sirtuins as Regulators of the Yeast Metabolic Network

(2012) Markus Ralser et al.   Frontiers in Pharmacology

Mitophagy in neurodegeneration and aging

(2012) Konstantinos Palikaras et al.   Frontiers in Genetics

Lack of Ach1 CoA-Transferase Triggers Apoptosis and Decreases Chronological Lifespan in Yeast

(2012) Ivan Orlandi et al.   Frontiers in Oncology

Mitophagy: A Complex Mechanism of Mitochondrial Removal

(2011) Ivana Novak   ANTIOXIDANTS & REDOX SIGNALING

A longer and healthier life with TOR down-regulation: genetics and drugs: Figure 1

(2011) Ivana Bjedov et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Selective autophagy in the maintenance of cellular homeostasis in aging organisms

(2011) Vanessa M. Hubbard et al.   BIOGERONTOLOGY

PiNGO: a Cytoscape plugin to find candidate genes in biological networks

(2011) M. Smoot et al.   BIOINFORMATICS

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Key Players and Their Role During Mitochondrial Iron-Sulfur Cluster Biosynthesis

(2011) Swati Rawat et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mitochondria, reactive oxygen species, and chronological aging: A message from yeast

(2011) Yong Pan   EXPERIMENTAL GERONTOLOGY

Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane

(2011) Saori R. Yoshii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial DNA mutations in disease and aging

(2011) Chan Bae Park et al.   JOURNAL OF CELL BIOLOGY

Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2

(2011) N. Mendl et al.   JOURNAL OF CELL SCIENCE

Life Span Extension and H2O2 Resistance Elicited by Caloric Restriction Require the Peroxiredoxin Tsa1 in Saccharomyces cerevisiae

(2011) Mikael Molin et al.   MOLECULAR CELL

Mitochondrial dysfunction in brain aging: Role of oxidative stress and cardiolipin

(2011) Giuseppe Paradies et al.   NEUROCHEMISTRY INTERNATIONAL

Replicative Age Induces Mitotic Recombination in the Ribosomal RNA Gene Cluster of Saccharomyces cerevisiae

(2011) Derek L. Lindstrom et al.   PLoS Genetics

The Interplay Between Mitochondrial Dynamics and Mitophagy

(2010) Gilad Twig et al.   ANTIOXIDANTS & REDOX SIGNALING

Aging: ROS or TOR

(2010) Mikhail V Blagosklonny   CELL CYCLE

Quantitation of (a)symmetric inheritance of functional and of oxidatively damaged mitochondrial aconitase in the cell division of old yeast mother cells

(2010) Harald Klinger et al.   EXPERIMENTAL GERONTOLOGY

Perspectives on the mitochondrial etiology of replicative aging in yeast

(2010) Ana Ugidos et al.   EXPERIMENTAL GERONTOLOGY

Mitophagy in yeast: actors and physiological roles

(2010) Ingrid Bhatia-Kiššová et al.   FEMS YEAST RESEARCH

Yeast as a model to study mitochondrial mechanisms in ageing

(2010) Mario H. Barros et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Regulatory crosstalk of the metabolic network

(2010) Nana-Maria Grüning et al.   TRENDS IN BIOCHEMICAL SCIENCES

Genome-Wide Screen in Saccharomyces cerevisiae Identifies Vacuolar Protein Sorting, Autophagy, Biosynthetic, and tRNA Methylation Genes Involved in Life Span Regulation

(2010) Paola Fabrizio et al.   PLoS Genetics

Lipid peroxidation in relation to ageing and the role of endogenous aldehydes in diabetes and other age-related diseases

(2009) L.F. Dmitriev et al.   AGEING RESEARCH REVIEWS

Mitochondrial Dysfunction Leads to Nuclear Genome Instability via an Iron-Sulfur Cluster Defect

(2009) Joshua R. Veatch et al.   CELL

Function and biogenesis of iron–sulphur proteins

(2009) Roland Lill   NATURE

Metabolic reconfiguration precedes transcriptional regulation in the antioxidant response

(2009) Markus Ralser et al.   NATURE BIOTECHNOLOGY

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Dynamics and diversity in autophagy mechanisms: lessons from yeast

(2009) Hitoshi Nakatogawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Oxidative Inactivation of Mitochondrial Aconitase Results in Iron and H2O2-Mediated Neurotoxicity in Rat Primary Mesencephalic Cultures

(2009) David Cantu et al.   PLoS One

Iron–sulfur cluster biosynthesis in bacteria: Mechanisms of cluster assembly and transfer

(2008) Marc Fontecave et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast

(2008) A. M. Aerts et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Quantification of random mutations in the mitochondrial genome

(2008) Marc Vermulst et al.   METHODS