Article
Genetics & Heredity
Benoit Laurent, Magalie Moinard, Cathy Spataro, Sylvain Chereau, Enric Zehraoui, Richard Blanc, Pauline Lasserre, Nadia Ponts, Marie Foulongne-Oriol
Summary: This study aimed to characterize the genetic basis of aggressiveness variation observed in Fusarium graminearum. A major QTL was identified on chromosome I, explaining up to 90% of the variance for disease severity. Four candidate genes were selected based on the hypothesis that non-synonymous mutations affecting protein function may be responsible for phenotypic differences. Finally, a new mutation was identified and functionally validated in the FgVe1 gene, coding for a velvet protein involved in pathogenicity and secondary metabolism production in fungi.
FUNGAL GENETICS AND BIOLOGY
(2021)
Review
Microbiology
Holly P. Bartholomew, Michael Bradshaw, Wayne M. Jurick, Jorge M. Fonseca
Summary: Understanding the impact of various toxins on the beneficial and harmful microorganisms within the host microbiome is essential and can lead to the identification of safe analogs for antimicrobial activity to reduce fruit decay. Exploring the composition of the microbial carposphere of host plants may help in developing a microbial consortium to maintain quality during storage and reduce mycotoxin contamination.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Plant Sciences
Sean P. O'Mara, Karen Broz, Erin M. Schwister, Lovepreet Singh, Yanhong Dong, J. Mitch Elmore, H. Corby Kistler
Summary: This study reveals that the deletion of membrane-bound transporters in the plant pathogenic fungus Fusarium graminearum leads to reduced accumulation of the mycotoxin deoxynivalenol (DON) and decreased disease symptoms on wheat. The ATP-binding cassette (ABC) transporter gene Abc1 plays a major role in DON accumulation and virulence reduction. Heterologous expression of F. graminearum transporters in yeast confirms Abc1 as a major mechanism of DON resistance and suggests the involvement of multiple transporters in resistance to other compounds. These findings provide valuable insights for developing novel management techniques for Fusarium head blight and other destructive plant diseases.
Article
Plant Sciences
Imane Laraba, Todd J. Ward, Miroslava Cuperlovic-Culf, Hilda Azimi, Pengcheng Xi, Susan P. Mccormick, William T. Hay, Guixia Hao, Martha M. Vaughan
Summary: Fusarium head blight (FHB) is an economically devastating fungal disease of wheat and other small grains, with Fusarium graminearum (Fg) being the predominant etiological agent. In this study, three genetic populations of Fg in North America were identified, and their differences in aggressiveness and mycotoxin production were assessed. The NA3 population was found to be less aggressive than NA1 and NA2 populations but had a similar mycotoxigenic potential. Furthermore, the severity difference in NA3 was not solely due to mycotoxin production or host defense mechanisms.
Review
Food Science & Technology
Debora Muratori Holanda, Sung Woo Kim
Summary: The occurrence of mycotoxins, especially aflatoxins and Fusarium toxins, poses a challenge to pig production globally. Their toxic effects impair the health and growth of pigs. Effective mycotoxin-detoxifying agents are needed to improve pig health and performance, and enhance the sustainable use of crops.
Article
Environmental Sciences
Lihong Xie, Yanfei Wu, Yong Wang, Yueming Jiang, Bao Yang, Xuewu Duan, Taotao Li
Summary: The research demonstrates that fumonisin B1 increases the aggressiveness of Fusarium proliferatum on banana fruit and inhibits the defense ability of banana fruit by affecting enzyme activities and cell death-related genes. This leads to a reduction in disease resistance of banana fruit and acceleration of cell death, possibly through altering hydrogen peroxide content. The study sheds light on the potential virulence factor role of fumonisins in modulating fruit defense response.
ENVIRONMENTAL POLLUTION
(2021)
Article
Agronomy
Christine van Capelle, Friederike Meyer-Wolfarth, Torsten Meiners, Stefan Schrader
Summary: In this study, the bioregulatory performance of the earthworm species Lumbricus terrestris in suppressing Fusarium species and reducing mycotoxins in maize mulch layer was analyzed. The results showed that Lumbricus terrestris had a species-specific regulation on Fusarium species and significantly accelerated the degradation of mycotoxins. Fine chopping of the chaff did not affect the earthworms' regulatory capacity.
Article
Biology
Yanxiang Zhao, Huilin Sun, Jingwen Li, Chao Ju, Jinguang Huang
Summary: This study identified and functionally characterized a Zn(II)2-Cys6 transcription factor FgAtrR in F. graminearum. The deletion of FgAtrR resulted in faster radial growth with pigmentation defects, reduced conidial production, and the inability to form perithecia. Deletion of FgAtrR also severely impaired the pathogenicity of the mutant on wheat spikes and corn silks with reduced deoxynivalenol production. Furthermore, the tolerance to azole fungicides was significantly decreased in the deletion mutant, indicating the role of FgAtrR in intrinsic resistance.
Article
Cell Biology
Jiale Shi, Min Zhang, Liwen Gao, Qian Yang, Hazem M. Kalaji, Sheng Qiang, Reto Jorg Strasser, Shiguo Chen
Summary: The necrotrophic fungus Alternaria alternata contains different pathotypes that produce different mycotoxins. The pathotype Ageratina adenophora secretes the non-host-selective toxin tenuazonic acid (TeA), which can cause necrosis in many plants. The study found that TeA-triggered cell death is essential for successful colonization and disease development in host leaves during infection with A. adenophora pathogens.
Review
Biochemistry & Molecular Biology
Jean-Marie Savignac, Vessela Atanasova, Sylvain Chereau, Veronique Ortega, Florence Richard-Forget
Summary: Fungal pathogens pose a major threat to cereal cultivation and the safety of harvested kernels. Enhancing crop resistance to fungal diseases and mycotoxin accumulation is therefore crucial. Tocochromanols, a type of metabolite found in cereal kernels, may play a role in plant-fungal pathogen interactions, based on their antioxidant properties and potential to inhibit fungal growth and mycotoxin production.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Agriculture, Dairy & Animal Science
Huiying Sun, Ziqi He, Dongwei Xiong, Miao Long
Summary: This article summarizes the newly discovered degrading enzymes that can degrade four common mycotoxins in the past five years, and explains their degradation mechanisms and positive effects on animal production.
Review
Microbiology
Taotao Li, Xinguo Su, Hongxia Qu, Xuewu Duan, Yueming Jiang
Summary: Fumonisins are important mycotoxins with widespread occurrence and potential health threats. Research focuses on controlling fumonisin contamination in food supply chains, with significant progress in biochemistry, enzymology, and genetic regulation of fumonisin biosynthesis using molecular technology. New insights into the roles of fumonisins in the interaction between fungi and plant hosts have been reported.
CRITICAL REVIEWS IN MICROBIOLOGY
(2022)
Article
Entomology
Prajakta P. Kokate, Thomas Werner
Summary: Certain mycophagous Drosophila species are the only known eukaryotes that can tolerate some highly potent mycotoxins. However, mycotoxin tolerance may be a costly trait to maintain and is associated with fitness costs. This study provides evidence of an association between local adaptation and mycotoxin tolerance, as well as the negative effects of mycotoxin tolerance on larval competitive ability and survival.
JOURNAL OF INSECT SCIENCE
(2023)
Article
Multidisciplinary Sciences
Jacopo Marchi, Michael Laessig, Aleksandra M. Walczak, Thierry Mora
Summary: The coevolution between pathogens and host populations in a finite-dimensional antigenic space results in the emergence of an antigenic wave driven and guided by cross-reactivity. This coevolution generates a new timescale, impacting the predictability of epidemiological and evolutionary forecasting of vaccines.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Chemistry, Analytical
Murugavelu Marimuthu, Selva Sharma Arumugam, Tianhui Jiao, Devaraj Sabarinathan, Huanhuan Li, Quansheng Chen
Summary: This review focuses on the applications of metal organic framework (MOF)-based sensors in the field of food safety. MOF sensors, known for their high absorbency, strong luminous features, and cost-effectiveness, are considered promising complementary and alternative analysis methods to conventional detection methods. The review summarizes various MOF-based sensors, describes their principles, and explores their applications in detecting pesticides, antibiotics, pathogens, and mycotoxins, considering their sensitivity and multiplexing capability. The limitations and challenges of using MOF-based sensors for efficient and precise evaluation of food are also discussed.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Biodiversity Conservation
Rosalie Sabburg, Friday Obanor, Elizabeth Aitken, Sukumar Chakraborty
GLOBAL CHANGE BIOLOGY
(2015)
Article
Plant Sciences
K. Boyd-Wilson, F. Obanor, R. C. Butler, P. Harris-Virgin, G. I. Langford, J. T. Smith, M. Walter
AUSTRALASIAN PLANT PATHOLOGY
(2013)
Article
Plant Sciences
Friday O. Obanor, Monika Walter, E. Eirian Jones, Marlene V. Jaspers
AUSTRALASIAN PLANT PATHOLOGY
(2013)
Article
Agronomy
Ismail Erper, Carlos Agusti-Brisach, Berna Tunali, Josep Armengol
EUROPEAN JOURNAL OF PLANT PATHOLOGY
(2013)
Article
Agronomy
P. Melloy, E. Aitken, J. Luck, S. Chakraborty, F. Obanor
EUROPEAN JOURNAL OF PLANT PATHOLOGY
(2014)
Article
Mycology
Friday Obanor, G. Erginbas-Orakci, B. Tunali, J. M. Nicol, S. Chakraborty
Article
Microbiology
Elif Cepni, Berna Tunali, Filiz Gurel
JOURNAL OF BASIC MICROBIOLOGY
(2013)
Article
Plant Sciences
Sukumar Chakraborty, Friday Obanor, Rhyannyn Westecott, Krishanthi Abeywickrama
Article
Agronomy
F. O. ab Obanor, M. Walter, E. E. a Jones, M. V. a Jaspers
Article
Agronomy
F. Obanor, S. Neate, S. Simpfendorfer, R. Sabburg, P. Wilson, S. Chakraborty
Article
Agronomy
F. Obanor, S. Chakraborty
Article
Agronomy
M. Khudhair, P. Melloy, D. J. Lorenz, F. Obanor, E. Aitken, S. Datta, J. Luck, G. Fitzgerald, S. Chakraborty
Proceedings Paper
Agronomy
R. Sabburg, F. Obanor, E. Aitken
AGRICULTURE AND CLIMATE CHANGE - ADAPTING CROPS TO INCREASED UNCERTAINTY (AGRI 2015)
(2015)