Tapping the treasure of intracellular oncotargets with immunotherapy

Engineering the First Chimeric Antibody in Targeting Intracellular PRL-3 Oncoprotein for Cancer Therapy in Mice

(2015) Ke Guo et al.   Oncotarget

Unconventional protein secretion: an evolving mechanism

(2013) Vivek Malhotra   EMBO JOURNAL

Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia

(2013) Jung Eun Park et al.   EMBO Molecular Medicine

Targeting the Intracellular WT1 Oncogene Product with a Therapeutic Human Antibody

(2013) T. Dao et al.   Science Translational Medicine

Intracellular Tumor-Associated Antigens Represent Effective Targets for Passive Immunotherapy

(2012) T. Noguchi et al.   CANCER RESEARCH

Targeting Intracellular Oncoproteins with Antibody Therapy or Vaccination

(2011) K. Guo et al.   Science Translational Medicine

Hidden Immunotherapy Targets Challenge Dogma

(2011) S. Ferrone   Science Translational Medicine

Monoclonal antibodies target intracellular PRL phosphatases to inhibit cancer metastases in mice

(2010) Ke Guo et al.   CANCER BIOLOGY & THERAPY

PRL-3 phosphatase and cancer metastasis

(2010) Abdul Qader O. Al-Aidaroos et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

(2010) D. L. Mallery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

(2009) M. A. Cheever et al.   CLINICAL CANCER RESEARCH

K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer

(2008) Christos S. Karapetis et al.   NEW ENGLAND JOURNAL OF MEDICINE