Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia

Engineering the First Chimeric Antibody in Targeting Intracellular PRL-3 Oncoprotein for Cancer Therapy in Mice

(2015) Ke Guo et al.   Oncotarget

Targeting the Intracellular WT1 Oncogene Product with a Therapeutic Human Antibody

(2013) T. Dao et al.   Science Translational Medicine

Awaiting a New Era of Cancer Immunotherapy

(2012) C. W. Hong et al.   CANCER RESEARCH

Leukemia Gene Atlas – A Public Platform for Integrative Exploration of Genome-Wide Molecular Data

(2012) Katja Hebestreit et al.   PLoS One

Risk stratification of intermediate-risk acute myeloid leukemia: integrative analysis of a multitude of gene mutation and gene expression markers

(2011) V. Rockova et al.   BLOOD

PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

(2011) Jianbiao Zhou et al.   PLoS One

Targeting Intracellular Oncoproteins with Antibody Therapy or Vaccination

(2011) K. Guo et al.   Science Translational Medicine

Hidden Immunotherapy Targets Challenge Dogma

(2011) S. Ferrone   Science Translational Medicine

Monoclonal antibodies target intracellular PRL phosphatases to inhibit cancer metastases in mice

(2010) Ke Guo et al.   CANCER BIOLOGY & THERAPY

PRL-3 phosphatase and cancer metastasis

(2010) Abdul Qader O. Al-Aidaroos et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Gene expression profiling in AML with normal karyotype can predict mutations for molecular markers and allows novel insights into perturbed biological pathways

(2010) A Kohlmann et al.   LEUKEMIA

Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα-induced granulocytic differentiation through c-Jun in AML

(2010) J A Pulikkan et al.   LEUKEMIA

Drug resistance in mutant FLT3-positive AML

(2010) E Weisberg et al.   ONCOGENE

Constitutive Suppression of PRL-3 Inhibits Invasion and Proliferation of Gastric Cancer Cell in vitro and in vivo

(2010) Yasuko Matsukawa et al.   PATHOBIOLOGY

FLT3 inhibition and mechanisms of drug resistance in mutant FLT3-positive AML

(2009) Ellen Weisberg et al.   DRUG RESISTANCE UPDATES

PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin β1-ERK1/2 and-MMP2 signaling

(2009) Lirong Peng et al.   Molecular Cancer

An Anticancer Effect of Curcumin Mediated by Down-Regulating Phosphatase of Regenerating Liver-3 Expression on Highly Metastatic Melanoma Cells

(2009) L. Wang et al.   MOLECULAR PHARMACOLOGY

PRL-3 facilitates angiogenesis and metastasis by increasing ERK phosphorylation and up-regulating the levels and activities of Rho-A/C in lung cancer

(2009) Jian Ming et al.   PATHOLOGY

Prognostic Significance of Phosphatase of Regenerating Liver-3 Expression in Ovarian Cancer

(2009) Tingting Ren et al.   PATHOLOGY & ONCOLOGY RESEARCH

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

(2008) K. H. Metzeler et al.   BLOOD

PRL PTPs: mediators and markers of cancer progression

(2008) Darrell C. Bessette et al.   CANCER AND METASTASIS REVIEWS

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

(2008) R. G.W. Verhaak et al.   HAEMATOLOGICA

Gene Expression With Prognostic Implications in Cytogenetically Normal Acute Myeloid Leukemia

(2008) Claudia D. Baldus et al.   SEMINARS IN ONCOLOGY

Prognostic Implications of Gene Mutations in Acute Myeloid Leukemia With Normal Cytogenetics

(2008) Verena Gaidzik et al.   SEMINARS IN ONCOLOGY

Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells

(2007) U.-M. Fagerli et al.   BLOOD