Pleckstrin homology (PH) like domains - versatile modules in protein-protein interaction platforms

Structural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106

(2012) Dan Su et al.   NATURE

Dynamin, a membrane-remodelling GTPase

(2012) Shawn M. Ferguson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A history of TFIIH: Two decades of molecular biology on a pivotal transcription/repair factor

(2011) Jean-Marc Egly et al.   DNA REPAIR

Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor

(2011) Qing Lu et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal structure of nucleotide-free dynamin

(2011) Katja Faelber et al.   NATURE

The crystal structure of dynamin

(2011) Marijn G. J. Ford et al.   NATURE

ARF family G proteins and their regulators: roles in membrane transport, development and disease

(2011) Julie G. Donaldson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1

(2010) Bingke Yu et al.   CELL

Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients

(2010) Jon A Kenniston et al.   EMBO JOURNAL

Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin

(2010) Stefan Welti et al.   HUMAN MUTATION

Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation

(2010) Zhe Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

(2010) Wen-I Wu et al.   PLoS One

Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless

(2010) Jodi Gureasko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas

(2009) K Shoji et al.   BRITISH JOURNAL OF CANCER

Interaction between the SifA Virulence Factor and Its Host Target SKIP Is Essential forSalmonellaPathogenesis

(2009) Lautaro Diacovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Pleckstrin Homology Domains: A Prokaryotic Origin for the PH Domain

(2009) Qingping Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Insights into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2

(2009) Tom D. Bunney et al.   MOLECULAR CELL

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14

(2009) Rafael S Depetris et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling

(2009) Vytas A. Bankaitis et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structure and Function of Salmonella SifA Indicate that Its Interactions with SKIP, SseJ, and RhoA Family GTPases Induce Endosomal Tubulation

(2008) Maikke B. Ohlson et al.   Cell Host & Microbe

Structural insight into the TFIIE–TFIIH interaction: TFIIE and p53 share the binding region on TFIIH

(2008) Masahiko Okuda et al.   EMBO JOURNAL

Crucial structural role for the PH and C1 domains of the Vav1 exchange factor

(2008) Jonathan Rapley et al.   EMBO REPORTS

Structure Basis and Unconventional Lipid Membrane Binding Properties of the PH-C1 Tandem of Rho Kinases

(2008) Wenyu Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rac Regulates Its Effector Phospholipase Cγ2through Interaction with a Split Pleckstrin Homology Domain

(2008) Claudia Walliser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Skap-hom Dimerization and PH Domains Comprise a 3′-Phosphoinositide-Gated Molecular Switch

(2008) Kenneth D. Swanson et al.   MOLECULAR CELL

General and Versatile Autoinhibition of PLC Isozymes

(2008) Stephanie N. Hicks et al.   MOLECULAR CELL

The Salmonella virulence protein SifA is a G protein antagonist

(2008) L. K. Jackson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA