The language of SH2 domain interactions defines phosphotyrosine-mediated signal transduction

Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin

(2012) Manjeet Mukherjee et al.   EMBO JOURNAL

p85α SH2 Domain Phosphorylation by IKK Promotes Feedback Inhibition of PI3K and Akt in Response to Cellular Starvation

(2012) William C. Comb et al.   MOLECULAR CELL

Simultaneous Binding of Two Peptidyl Ligands by a Src Homology 2 Domain

(2011) Yanyan Zhang et al.   BIOCHEMISTRY

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

(2011) Xuxiao Zhang et al.   MOLECULAR CELL

Solution Structure of Tensin2 SH2 Domain and Its Phosphotyrosine-Independent Interaction with DLC-1

(2011) Kun Dai et al.   PLoS One

Inhibition of PI3K binding to activators by serine phosphorylation of PI3K regulatory subunit p85  Src homology-2 domains

(2011) J. Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SH2 Domain-Containing Proteins in 21 Species Establish the Provenance and Scope of Phosphotyrosine Signaling in Eukaryotes

(2011) B. A. Liu et al.   Science Signaling

Spatial Exclusivity Combined with Positive and Negative Selection of Phosphorylation Motifs Is the Basis for Context-Dependent Mitotic Signaling

(2011) J. Alexander et al.   Science Signaling

Phosphotyrosine Signaling: Evolving a New Cellular Communication System

(2010) Wendell A. Lim et al.   CELL

Recognition and Specificity Determinants of the Human Cbx Chromodomains

(2010) Lilia Kaustov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SH2 Domains Recognize Contextual Peptide Sequence Information to Determine Selectivity

(2010) Bernard A. Liu et al.   MOLECULAR & CELLULAR PROTEOMICS

Characterizing Tyrosine Phosphorylation Signaling in Lung Cancer Using SH2 Profiling

(2010) Kazuya Machida et al.   PLoS One

Combining peptide recognition specificity and context information for the prediction of the 14-3-3-mediated interactome in S. cerevisiae and H. sapiens

(2010) Simona Panni et al.   PROTEOMICS

Loops Govern SH2 Domain Specificity by Controlling Access to Binding Pockets

(2010) T. Kaneko et al.   Science Signaling

The Selectivity of Receptor Tyrosine Kinase Signaling Is Controlled by a Secondary SH2 Domain Binding Site

(2009) Jae Hyun Bae et al.   CELL

Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCγ1

(2009) Lie Min et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart

(2009) J. D. Scott et al.   SCIENCE

Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates

(2008) Cherlyn Ng et al.   EMBO JOURNAL

Pyruvate kinase M2 is a phosphotyrosine-binding protein

(2008) Heather R. Christofk et al.   NATURE

Contextual Specificity in Peptide-Mediated Protein Interactions

(2008) Amelie Stein et al.   PLoS One

Linear Motif Atlas for Phosphorylation-Dependent Signaling

(2008) M. L. Miller et al.   Science Signaling