SH2 Domains Recognize Contextual Peptide Sequence Information to Determine Selectivity

Features and development ofCoot

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Ligand docking and binding site analysis with PyMOL and Autodock/Vina

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The Selectivity of Receptor Tyrosine Kinase Signaling Is Controlled by a Secondary SH2 Domain Binding Site

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Linear combinations of docking affinities explain quantitative differences in RTK signaling

(2009) Andrew Gordus et al.   Molecular Systems Biology

Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCγ1

(2009) Lie Min et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Models of Tandem Src Homology 2 Domain Interactions and Application to Phosphoinositide 3-Kinase

(2008) Dipak Barua et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

(2008) Nicole King et al.   NATURE

Contextual Specificity in Peptide-Mediated Protein Interactions

(2008) Amelie Stein et al.   PLoS One

The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan

(2008) G. Manning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brk is coamplified with ErbB2 to promote proliferation in breast cancer

(2008) B. Xiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of the phospho-tyrosine signaling machinery in premetazoan lineages

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