AML1-ETO triggers epigenetic activation of early growth response gene l, inducing apoptosis in t(8;21) acute myeloid leukemia

The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML

(2013) Florian H. Heidel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis

(2013) Xiao-Jian Sun et al.   NATURE

A Natural-Like Synthetic Small Molecule Impairs Bcr-Abl Signaling Cascades and Induces Megakaryocyte Differentiation in Erythroleukemia Cells

(2013) Silvia Turroni et al.   PLoS One

A Histone Acetyltransferase p300 Inhibitor C646 Induces Cell Cycle Arrest and Apoptosis Selectively in AML1-ETO-Positive AML Cells

(2013) Xiao-ning Gao et al.   PLoS One

Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway

(2012) Y. Li et al.   BLOOD

Chromatin accessibility, p300, and histone acetylation define PML-RAR  and AML1-ETO binding sites in acute myeloid leukemia

(2012) S. Saeed et al.   BLOOD

High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia

(2012) K. H. Metzeler et al.   BLOOD

Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

(2012) Jay P. Patel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice

(2011) A. M. Ramirez-Herrick et al.   BLOOD

MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia

(2011) X-N Gao et al.   ONCOGENE

The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

(2011) L. Wang et al.   SCIENCE

Dexamethasone Synergizes with Lenalidomide to Inhibit Multiple Myeloma Tumor Growth, But Reduces Lenalidomide-Induced Immunomodulation of T and NK Cell Function

(2010) A. K. Gandhi et al.   CURRENT CANCER DRUG TARGETS

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Core binding factor acute myeloid leukemia (CBF-AML): is high-dose Ara-C (HDAC) consolidation as effective as you think?

(2009) Hervé Dombret et al.   CURRENT OPINION IN HEMATOLOGY

Src family kinase gene targets during myeloid differentiation: identification of the EGR-1 gene as a direct target

(2009) J E Jones et al.   LEUKEMIA

Thalidomide inhibits leukemia cell invasion and migration by upregulation of early growth response gene 1

(2009) Peng Liu et al.   LEUKEMIA & LYMPHOMA

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

(2008) R. G.W. Verhaak et al.   HAEMATOLOGICA

Leukemia suppressor function of Egr-1 is dependent on transforming oncogene

(2008) J D Gibbs et al.   LEUKEMIA

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

(2008) T VAISSIERE et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH