Role of proteoglycans in the regulation of the skeletal muscle fibrotic response

Fell-Muir lecture: connective tissue growth factor (CCN2) - a pernicious and pleiotropic player in the development of kidney fibrosis

(2012) Roger M. Mason   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

PAI-1–regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy

(2012) Esther Ardite et al.   JOURNAL OF CELL BIOLOGY

Targeting the Activin Type IIB Receptor to Improve Muscle Mass and Function in the mdx Mouse Model of Duchenne Muscular Dystrophy

(2011) Emidio E. Pistilli et al.   AMERICAN JOURNAL OF PATHOLOGY

Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological Activity

(2011) Cecilia Vial et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Internal Region Leucine-rich Repeat 6 of Decorin Interacts with Low Density Lipoprotein Receptor-related Protein-1, Modulates Transforming Growth Factor (TGF)-β-dependent Signaling, and Inhibits TGF-β-dependent Fibrotic Response in Skeletal Muscles

(2011) Claudio Cabello-Verrugio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles

(2011) Claudio Cabello-Verrugio et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy

(2011) María Gabriela Morales et al.   JOURNAL OF PATHOLOGY

CCN2/decorin interactions: a novel approach to combating fibrosis?

(2011) Andrew Leask   Journal of Cell Communication and Signaling

Aberrant repair and fibrosis development in skeletal muscle

(2011) Christopher J Mann et al.   Skeletal Muscle

Phase 1 Study of Anti-CTGF Monoclonal Antibody in Patients with Diabetes and Microalbuminuria

(2010) S. G. Adler et al.   Clinical Journal of the American Society of Nephrology

Regulation and dysregulation of fibrosis in skeletal muscle

(2010) Antonio L. Serrano et al.   EXPERIMENTAL CELL RESEARCH

Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting

(2010) Achilleas D. Theocharis et al.   FEBS Journal

Proteoglycans in health and disease: emerging concepts and future directions

(2010) Renato V. Iozzo et al.   FEBS Journal

Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans

(2010) Renato V. Iozzo et al.   FEBS Journal

Integrin expression and function in the response of primary culture hepatic stellate cells to connective tissue growth factor (CCN2)

(2010) Guangcun Huang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Prevention of muscle fibrosis and myonecrosis inmdxmice by suramin, a TGF-β1 blocker

(2010) Ana Paula Tiemi Taniguti et al.   MUSCLE & NERVE

Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice

(2010) A. R. Amenta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Connective tissue growth factor: Context-dependent functions and mechanisms of regulation

(2009) Iwona Cicha et al.   BIOFACTORS

Matrix Metalloproteinase-2-deficient Fibroblasts Exhibit an Alteration in the Fibrotic Response to Connective Tissue Growth Factor/CCN2 because of an Increase in the Levels of Endogenous Fibronectin

(2009) Cristian A. Droppelmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Renin-angiotensin system in the pathogenesis of liver fibrosis

(2009) Regina Maria Pereira et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis

(2008) Xu Shi-Wen et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Fibrinogen drives dystrophic muscle fibrosis via a TGF /alternative macrophage activation pathway

(2008) B. Vidal et al.   GENES & DEVELOPMENT

Functions and mechanisms of action of CCN matricellular proteins

(2008) Chih-Chiun Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Novel regulatory mechanisms for the proteoglycans decorin and biglycan during muscle formation and muscular dystrophy

(2008) Enrique Brandan et al.   MATRIX BIOLOGY

Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone

(2008) Tidhar Turgeman et al.   NEUROMUSCULAR DISORDERS

Antisense inhibition of connective tissue growth factor (CTGF/CCN2) mRNA limits hypertrophic scarring without affecting wound healing in vivo

(2008) Mark Sisco et al.   WOUND REPAIR AND REGENERATION

Glypicans

(2008) Jorge Filmus et al.   GENOME BIOLOGY

Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation

(2007) Cecilia Vial et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY

Connective tissue growth factor is overexpressed in muscles of human muscular dystrophy

(2007) Guilian Sun et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES