CFTR: a hub for kinases and crosstalk of cAMP and Ca2+

A-Kinase Anchoring Protein-Calcineurin Signaling in Long-Term Depression of GABAergic Synapses

(2013) M. Dacher et al.   JOURNAL OF NEUROSCIENCE

Purinergic signaling in inflammatory cells: P2 receptor expression, functional effects, and modulation of inflammatory responses

(2013) Fenila Jacob et al.   Purinergic Signalling

Dynamics Intrinsic to Cystic Fibrosis Transmembrane Conductance Regulator Function and Stability

(2013) P. A. Chong et al.   Cold Spring Harbor Perspectives in Medicine

Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect

(2013) Valeria Rachela Villella et al.   Frontiers in Pharmacology

Coupling of epithelial Na+ and Cl− channels by direct and indirect activation by serine proteases

(2012) Veronika Gondzik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator

(2012) Alessandro Luciani et al.   Autophagy

CFTR mutations altering CFTR fragmentation

(2012) Kendra Tosoni et al.   BIOCHEMICAL JOURNAL

Molecular mechanisms of feedback inhibition of protein kinase A on intracellular cAMP accumulation

(2012) Jurgen Vandamme et al.   CELLULAR SIGNALLING

Can Correcting the ΔF508-CFTR Proteostasis-Defect Rescue CF Lung Disease?

(2012) C. W. Valle et al.   CURRENT MOLECULAR MEDICINE

Airway epithelial cells—Functional links between CFTR and anoctamin dependent Cl− secretion

(2012) Karl Kunzelmann et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase

(2012) J Darwin King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anoctamins are a family of Ca2+-activated Cl- channels

(2012) Y. Tian et al.   JOURNAL OF CELL SCIENCE

Cancer Risk in Cystic Fibrosis: A 20-Year Nationwide Study From the United States

(2012) Patrick Maisonneuve et al.   JNCI-Journal of the National Cancer Institute

Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia

(2012) Guido Veit et al.   MOLECULAR BIOLOGY OF THE CELL

A Chaperone Trap Contributes to the Onset of Cystic Fibrosis

(2012) Judith A. Coppinger et al.   PLoS One

Lipoxin A4 Stimulates Calcium-Activated Chloride Currents and Increases Airway Surface Liquid Height in Normal and Cystic Fibrosis Airway Epithelia

(2012) Valia Verrière et al.   PLoS One

F508del-CFTR increases intracellular Ca2+ signaling that causes enhanced calcium-dependent Cl− conductance in cystic fibrosis

(2011) Joana Raquel Martins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

CFTR and TMEM16A are Separate but Functionally Related Cl- Channels

(2011) Jiraporn Ousingsawat et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL-8 secretion by cystic fibrosis airways

(2011) Haouaria Balghi et al.   FASEB JOURNAL

AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils

(2011) Hong-Beom Bae et al.   FASEB JOURNAL

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions

(2011) Daniel Lorentzen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity

(2011) S. Luz et al.   MOLECULAR AND CELLULAR BIOLOGY

Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression

(2011) Andrea Venerando et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

A genetic interaction between NDPK and AMPK in Dictyostelium discoideum that affects motility, growth and development

(2011) Sarah J. Annesley et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

KAP Degradation by Calpain Is Associated with CK2 Phosphorylation and Provides a Novel Mechanism for Cyclosporine A-Induced Proximal Tubule Injury

(2011) Olga Tornavaca et al.   PLoS One

Dictyostelium discoideum Nucleoside Diphosphate Kinase C Plays a Negative Regulatory Role in Phagocytosis, Macropinocytosis and Exocytosis

(2011) Sarah J. Annesley et al.   PLoS One

Anoctamin 6 is an essential component of the outwardly rectifying chloride channel

(2011) J. R. Martins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleoside Diphosphate Kinase B Knock-out Mice Have Impaired Activation of the K+Channel KCa3.1, Resulting in Defective T Cell Activation

(2010) Lie Di et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compartmentalized Cyclic Adenosine 3′,5′-Monophosphate at the Plasma Membrane Clusters PDE3A and Cystic Fibrosis Transmembrane Conductance Regulator into Microdomains

(2010) Himabindu Penmatsa et al.   MOLECULAR BIOLOGY OF THE CELL

Ebselen is a potent non-competitive inhibitor of extracellular nucleoside diphosphokinase

(2010) Lucia Semianrio-Vidal et al.   Purinergic Signalling

AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells

(2009) Kenneth R. Hallows et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR

(2009) J Darwin King et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epithelial Cells

(2009) Michael M. Myerburg et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cystic fibrosis transmembrane regulator fragments with the Phe508deletion exert a dual allosteric control over the master kinase CK2

(2009) Mario A. Pagano et al.   BIOCHEMICAL JOURNAL

Inhibition of Protein Kinase CK2 Closes the CFTR Cl- Channel, but has no Effect on the Cystic Fibrosis Mutant ΔF508-CFTR

(2009) Kate J. Treharne et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Small interfering peptide (siP) for in vivo examination of the developing lung interactonome

(2009) J. Craig Cohen et al.   DEVELOPMENTAL DYNAMICS

Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis

(2009) Kate J. Treharne et al.   FEBS LETTERS

Regulation of Rac1 by Simvastatin in Endothelial Cells

(2009) Ruqin Kou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP

(2009) Kate J. Treharne et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Clinical phenotype of cystic fibrosis patients with the G551D mutation

(2009) D.M. Comer et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells

(2008) Hélène Klein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Direct binding of cytosolic NDP kinases to membrane lipids is regulated by nucleotides

(2008) Kimberly A.P. Mitchell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

Mechanistic Insight into Control of CFTR by AMPK

(2008) Patthara Kongsuphol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three C-terminal residues from the sulphonylurea receptor contribute to the functional coupling between the KATPchannel subunits SUR2A and Kir6.2

(2008) Julien P. Dupuis et al.   JOURNAL OF PHYSIOLOGY-LONDON

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

Regulation of Cl− secretion by AMPK in vivo

(2008) Patthara Kongsuphol et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE