Characterizing the complexity of enzymes on the basis of their mechanisms and structures with a bio-computational analysis

The CoFactor database: organic cofactors in enzyme catalysis

(2010) Julia D. Fischer et al.   BIOINFORMATICS

The Structures and Physicochemical Properties of Organic Cofactors in Biocatalysis

(2010) Julia D. Fischer et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative Comparison of Catalytic Mechanisms and Overall Reactions in Convergently Evolved Enzymes: Implications for Classification of Enzyme Function

(2010) Daniel E. Almonacid et al.   PLoS Computational Biology

Metal-MACiE: a database of metals involved in biological catalysis

(2009) Claudia Andreini et al.   BIOINFORMATICS

Understanding the Functional Roles of Amino Acid Residues in Enzyme Catalysis

(2009) Gemma L. Holliday et al.   JOURNAL OF MOLECULAR BIOLOGY

Enzyme Catalysis by Hydrogen Bonds: The Balance between Transition State Binding and Substrate Binding in Oxyanion Holes

(2009) Luis Simón et al.   JOURNAL OF ORGANIC CHEMISTRY

Quantum Mechanical Design of Enzyme Active Sites

(2008) Xiyun Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

How much of protein sequence space has been explored by life on Earth?

(2008) D. T.F Dryden et al.   Journal of the Royal Society Interface

The CATH classification revisited--architectures reviewed and new ways to characterize structural divergence in superfamilies

(2008) A. L. Cuff et al.   NUCLEIC ACIDS RESEARCH

Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies

(2008) Ranyee A. Chiang et al.   PLoS Computational Biology