SAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling

Serum Amyloid A Induces CCL2 Production via Formyl Peptide Receptor-Like 1-Mediated Signaling in Human Monocytes

(2014) H. Y. Lee et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: TLR2 Is a Functional Receptor for Acute-Phase Serum Amyloid A

(2014) N. Cheng et al.   JOURNAL OF IMMUNOLOGY

Serum Amyloid A Promotes Lung Neutrophilia by Increasing IL-17A Levels in the Mucosa and γδ T Cells

(2013) Desiree Anthony et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

C-Reactive Protein and Serum Amyloid A Overexpression in Lung Tissues of Chronic Obstructive Pulmonary Disease Patients: A Case-Control Study

(2013) Jose Luis López-Campos et al.   International Journal of Medical Sciences

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

(2013) Emma L. Beckett et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Treating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways

(2013) Steven Bozinovski et al.   PHARMACOLOGY & THERAPEUTICS

Biasing the lipoxin A4/formyl peptide receptor 2 pushes inflammatory resolution

(2013) J. G. Filep   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses

(2013) S. N. Cooray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monocytes Control Second-Phase Neutrophil Emigration in Established Lipopolysaccharide-induced Murine Lung Injury

(2012) Kevin Dhaliwal et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Heme Oxygenase-1/CO as Protective Mediators in Cigarette Smoke- Induced Lung Cell Injury and Chronic Obstructive Pulmonary Disease

(2012) Tamas Dolinay et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Characterization of the Promoter and the Transcriptional Regulation of the Lipoxin A4 Receptor (FPR2/ALX) Gene in Human Monocytes and Macrophages

(2012) V. Waechter et al.   JOURNAL OF IMMUNOLOGY

Distinct Macrophage Subpopulations Characterize Acute Infection and Chronic Inflammatory Lung Disease

(2012) M. Duan et al.   JOURNAL OF IMMUNOLOGY

Serum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

(2012) S. Bozinovski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling

(2011) D. A. Hume et al.   BLOOD

Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation

(2011) Jason C Lenzo et al.   IMMUNOLOGY AND CELL BIOLOGY

Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2

(2011) Y Li et al.   ONCOGENE

Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

(2011) C. J. Harvey et al.   Science Translational Medicine

Carbonylation Caused by Cigarette Smoke Extract Is Associated with Defective Macrophage Immunity

(2010) Steven Bozinovski et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis

(2010) Paola Maderna et al.   FASEB JOURNAL

CD36 Is a Novel Serum Amyloid A (SAA) Receptor Mediating SAA Binding and SAA-induced Signaling in Human and Rodent Cells

(2010) Irina N. Baranova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Validation of SAA as a Potential Lung Cancer Biomarker and its Involvement in Metastatic Pathogenesis of Lung Cancer

(2010) Hye-Jin Sung et al.   JOURNAL OF PROTEOME RESEARCH

Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy

(2010) Hanne Van Gorp et al.   MOLECULAR IMMUNOLOGY

Lung environment determines unique phenotype of alveolar macrophages

(2009) Amanda M. Guth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Smoking-Dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of Chronic Obstructive Pulmonary Disease

(2009) R. Shaykhiev et al.   JOURNAL OF IMMUNOLOGY

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

DNA Vector Augments Inflammation in Epithelial Cells via EGFR-Dependent Regulation of TLR4 and TLR2

(2008) Kenneth Liu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Serum Amyloid A Is a Biomarker of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

(2007) Steven Bozinovski et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE