Ovarian LGR5 is critical for successful pregnancy

Structural basis for R-spondin recognition by LGR4/5/6 receptors

(2013) D. Wang et al.   GENES & DEVELOPMENT

Conditional deletion of Tsc1 in the female reproductive tract impedes normal oviductal and uterine function by enhancing mTORC1 signaling in mice

(2013) T. Daikoku et al.   MOLECULAR HUMAN REPRODUCTION

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche

(2013) Andrea Flesken-Nikitin et al.   NATURE

Mechanisms of implantation: strategies for successful pregnancy

(2012) Jeeyeon Cha et al.   NATURE MEDICINE

Kruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantation

(2012) X. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conditional Deletion of MSX Homeobox Genes in the Uterus Inhibits Blastocyst Implantation by Altering Uterine Receptivity

(2011) Takiko Daikoku et al.   DEVELOPMENTAL CELL

Cell-specific conditional deletion of Pten in the uterus results in differential phenotypes

(2011) Takiko Daikoku et al.   GYNECOLOGIC ONCOLOGY

Orphan receptors find a home

(2011) Walter Birchmeier   NATURE

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

(2011) K. S. Carmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

(2010) Nick Barker et al.   Cell Stem Cell

Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice

(2010) Yasushi Hirota et al.   JOURNAL OF CLINICAL INVESTIGATION

Wnt Signalling in Implantation, Decidualisation and Placental Differentiation – Review

(2010) S. Sonderegger et al.   PLACENTA

LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine

(2009) Marie Isabelle Garcia et al.   DEVELOPMENTAL BIOLOGY

In Pursuit of Leucine-Rich Repeat-Containing G Protein-Coupled Receptor-5 Regulation and Function in the Uterus

(2009) Xiaofei Sun et al.   ENDOCRINOLOGY

Lgr5 marks cycling, yet long-lived, hair follicle stem cells

(2008) Viljar Jaks et al.   NATURE GENETICS