Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression

Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs

(2011) Biji Mathew et al.   FASEB JOURNAL

NRF2 deficiency reduces life span of mice administered thoracic irradiation

(2011) Elizabeth L. Travis et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dissecting the Role of the S1P/S1PR Axis in Health and Disease

(2011) J.J. Aarthi et al.   JOURNAL OF DENTAL RESEARCH

Integrating mechanisms of pulmonary fibrosis

(2011) Thomas A. Wynn   JOURNAL OF EXPERIMENTAL MEDICINE

New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis

(2010) Lei Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Characterization of sphingosine-1-phosphate lyase activity by electrospray ionization–liquid chromatography/tandem mass spectrometry quantitation of (2E)-hexadecenal

(2010) Evgeny V. Berdyshev et al.   ANALYTICAL BIOCHEMISTRY

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

(2010) J. R. Ussher et al.   DIABETES

Transforming Growth Factor-β1 Induces Transdifferentiation of Myoblasts into Myofibroblasts via Up-Regulation of Sphingosine Kinase-1/S1P3 Axis

(2010) Francesca Cencetti et al.   MOLECULAR BIOLOGY OF THE CELL

Targeting the TGF- 1 Pathway to Prevent Normal Tissue Injury After Cancer Therapy

(2010) M. S. Anscher   ONCOLOGIST

Analysis of Development of Lesions in Mice with Serine Palmitoyltransferase (SPT) Deficiency

(2009) Etsuko OHTA et al.   EXPERIMENTAL ANIMALS

FTY720 Inhibits Ceramide Synthases and Up-regulates Dihydrosphingosine 1-Phosphate Formation in Human Lung Endothelial Cells

(2009) Evgeny V. Berdyshev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chiral Vinylphosphonate and Phosphonate Analogues of the Immunosuppressive Agent FTY720

(2009) Xuequan Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Pulmonary fibrosis: pathogenesis, etiology and regulation

(2009) M S Wilson et al.   Mucosal Immunology

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model

(2009) Minglun Li et al.   Radiation Oncology

The TGF-β1 dynamics during radiation therapy and its correlation to symptomatic radiation pneumonitis in lung cancer patients

(2009) Ji-Yoon Kim et al.   Radiation Oncology

Regulation of vascular permeability by sphingosine 1-phosphate

(2008) Lichun Wang et al.   MICROVASCULAR RESEARCH

Inactivation of AP1 Proteins by a Nuclear Serine Protease Precedes the Onset of Radiation-Induced Fibrosing Alveolitis1

(2008) Michael G. Haase et al.   RADIATION RESEARCH