Hyperthermophilic asparaginase mutants with enhanced substrate affinity and antineoplastic activity: structural insights on their mechanism of action

Role of loop dynamics in thermal stability of mesophilic and thermophilic adenylosuccinate synthetase: A molecular dynamics and normal mode analysis study

(2011) Satyavani Vemparala et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Asparaginase revisited

(2011) Henk van den Berg   LEUKEMIA & LYMPHOMA

A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity

(2011) Sonia Y. Lam et al.   PLOS BIOLOGY

Structural stability and functional analysis of L-asparaginase from Pyrococcus furiosus

(2010) S. Bansal et al.   BIOCHEMISTRY-MOSCOW

Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity

(2010) M. N. Offman et al.   BLOOD

Engineering thermal stability of l-asparaginase by in vitro directed evolution

(2009) Georgia A. Kotzia et al.   FEBS Journal

L-Asparaginase encapsulated intact erythrocytes for treatment of acute lymphoblastic leukemia (ALL)

(2009) Young Min Kwon et al.   JOURNAL OF CONTROLLED RELEASE

Withania somnifera(Ashwagandha): a Novel Source of L-asparaginase

(2009) Vishal P. Oza et al.   Journal of Integrative Plant Biology

Effect of L-asparaginase on acrylamide mitigation in a fried-dough pastry model

(2009) Kristína Kukurová et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Structural and functional insights into Erwinia carotovora l-asparaginase

(2008) Anastassios C. Papageorgiou et al.   FEBS Journal

The effect of asparaginase on acrylamide formation in French fries

(2008) Franco Pedreschi et al.   FOOD CHEMISTRY