Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis
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Title
Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis
Authors
Keywords
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Journal
FASEB JOURNAL
Volume 25, Issue 10, Pages 3661-3673
Publisher
FASEB
Online
2011-06-25
DOI
10.1096/fj.10-180190
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- (2009) A A Mian et al. LEUKEMIA
- Cathepsin B release after imatinib-mediated lysosomal membrane permeabilization triggers BCR–ABL cleavage and elimination of chronic myelogenous leukemia cells
- (2009) A Puissant et al. LEUKEMIA
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- (2008) Rebecca L. Shaner et al. JOURNAL OF LIPID RESEARCH
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Differential Effects of Glycolipid Biosynthesis Inhibitors on Ceramide-Induced Cell Death in Neuroblastoma Cells
- (2003) Erhard Bieberich et al. JOURNAL OF NEUROCHEMISTRY
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