Antibiotic adjuvants: multicomponent anti-infective strategies

Emerging Antimicrobial Resistance in Neisseria gonorrhoeae: Urgent Need to Strengthen Prevention Strategies

(2013) Kimberly A. Workowski et al.   ANNALS OF INTERNAL MEDICINE

Potent Synergy and Sustained Bactericidal Activity of a Vancomycin-Colistin Combination versus Multidrug-Resistant Strains of Acinetobacter baumannii

(2010) N. C. Gordon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synergistic Effects between Conventional Antibiotics and 2-Aminoimidazole-Derived Antibiofilm Agents

(2010) S. A. Rogers et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production

(2010) J. H. Moffatt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Current understanding of fatty acid biosynthesis and the acyl carrier protein

(2010) David I. Chan et al.   BIOCHEMICAL JOURNAL

Antibiotic Resistance by Enzyme Inactivation: From Mechanisms to Solutions

(2010) Gianfranco De Pascale et al.   CHEMBIOCHEM

Extensively Drug‐Resistant Tuberculosis: “There must be some kind of way out of here”

(2010) J. Peter Cegielski   CLINICAL INFECTIOUS DISEASES

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Antibiotic resistance in the environment: a link to the clinic?

(2010) Gerard D Wright   CURRENT OPINION IN MICROBIOLOGY

Potential role of the cardiovascular non-antibiotic (helper compound) amlodipine in the treatment of microbial infections: scope and hope for the future

(2010) K. Mazumdar et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Xanthoradone C, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2

(2010) Hiroyuki Yamazaki et al.   JOURNAL OF ANTIBIOTICS

Natural and synthetic compounds such as trimethoprim behave as inhibitors of efflux in Gram-negative bacteria

(2010) L. J. V. Piddock et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

(2010) Karthikeyan K Kumarasamy et al.   LANCET INFECTIOUS DISEASES

The antibiotics market

(2010) Bashar Hamad   NATURE REVIEWS DRUG DISCOVERY

Hospital-Acquired Infections Due to Gram-Negative Bacteria

(2010) Anton Y. Peleg et al.   NEW ENGLAND JOURNAL OF MEDICINE

D-Amino Acids Trigger Biofilm Disassembly

(2010) I. Kolodkin-Gal et al.   SCIENCE

Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli

(2010) Tobias Dörr et al.   PLOS BIOLOGY

Optimal Drug Synergy in Antimicrobial Treatments

(2010) Joseph Peter Torella et al.   PLoS Computational Biology

Controlling Bacterial Biofilms

(2009) Justin J. Richards et al.   CHEMBIOCHEM

Antibiotic resistance genes from the environment: a perspective through newly identified antibiotic resistance mechanisms in the clinical setting

(2009) R. Canteón   CLINICAL MICROBIOLOGY AND INFECTION

Multidrug-Resistant Gram-Negative Infections

(2009) Helen Giamarellou et al.   DRUGS

Experimental analyses of synergistic combinations of antibiotics with a recently recognised antibacterial agent, lacidipine

(2009) A. Dasgupta et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The anti-inflammatory non-antibiotic helper compound diclofenac: an antibacterial drug target

(2009) K. Mazumdar et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2: I. Taxonomy, fermentation, isolation and biological properties

(2009) Hiroyuki Yamazaki et al.   JOURNAL OF ANTIBIOTICS

Efficacy of colistin combination therapy in a mouse model of pneumonia caused by multidrug-resistant Pseudomonas aeruginosa

(2009) N. Aoki et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Has the era of untreatable infections arrived?

(2009) D. M. Livermore   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Enhancing antibiotic activity: a strategy to control Acinetobacter infections

(2009) S. Chusri et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Structure−Activity Relationships of Polymyxin Antibiotics

(2009) Tony Velkov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibiotic-Resistant Bugs in the 21st Century — A Clinical Super-Challenge

(2009) Cesar A. Arias et al.   NEW ENGLAND JOURNAL OF MEDICINE

Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis

(2009) J.-E. Hugonnet et al.   SCIENCE

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

New Disturbing Trend in Antimicrobial Resistance of Gram-Negative Pathogens

(2009) Jung Hun Lee et al.   PLoS Pathogens

Construction and Screening of a 2‐Aminoimidazole Library Identifies a Small Molecule Capable of Inhibiting and Dispersing Bacterial Biofilms across Order, Class, and Phylum

(2008) Steven A. Rogers et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanisms of drug efflux and strategies to combat them: Challenging the efflux pump of Gram-negative bacteria

(2008) Jean-Marie Pagès et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Towards Gram-negative antivirulence drugs: New inhibitors of HldE kinase

(2008) Nicolas Desroy et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and Screening of an Oroidin Library againstPseudomonas aeruginosaBiofilms

(2008) Justin J. Richards et al.   CHEMBIOCHEM

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Acinetobacter baumannii: Emergence of a Successful Pathogen

(2008) A. Y. Peleg et al.   CLINICAL MICROBIOLOGY REVIEWS

A domino effect in antifolate drug action in Escherichia coli

(2008) Yun Kyung Kwon et al.   Nature Chemical Biology

Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

(2008) Heidi Mulcahy et al.   PLoS Pathogens

Virtual Screening and Experimental Verification to Identify Potential Inhibitors of the ErmC Methyltransferase Responsible for Bacterial Resistance against Macrolide Antibiotics

(2007) Marcin Feder et al.   ChemMedChem

The Epidemic of Antibiotic-Resistant Infections: A Call to Action for the Medical Community from the Infectious Diseases Society of America

(2007) B. Spellberg et al.   CLINICAL INFECTIOUS DISEASES