The BCG replacement vaccine VPM1002: from drawing board to clinical trial

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013

(2013) Marko Babjuk et al.   EUROPEAN UROLOGY

Lysosomal cell death at a glance

(2013) S. Aits et al.   JOURNAL OF CELL SCIENCE

A Randomized, Controlled Dose-Finding Phase II Study of the M72/AS01 Candidate Tuberculosis Vaccine in Healthy PPD-Positive Adults

(2013) Jaime Montoya et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

The Tuberculosis Vaccine Candidate Bacillus Calmette-Guérin ΔureC::hly Coexpressing Human Interleukin-7 or -18 Enhances Antigen-Specific T Cell Responses in Mice

(2013) Martin Rao et al.   PLoS One

A Human Type 5 Adenovirus-Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity

(2013) F. Smaill et al.   Science Translational Medicine

Tuberculosis vaccines: Time to think about the next generation

(2013) Stefan H.E. Kaufmann   SEMINARS IN IMMUNOLOGY

Safety and immunogenicity of the recombinant BCG vaccine VPM1002 in a phase 1 open-label randomized clinical trial

(2013) Leander Grode et al.   VACCINE

Construction, characterization and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials

(2013) Ainhoa Arbues et al.   VACCINE

Recombinant live vaccine candidates against tuberculosis

(2012) Stefan HE Kaufmann et al.   CURRENT OPINION IN BIOTECHNOLOGY

The Changing Profile of Pediatric Meningitis at a Referral Centre in Cape Town, South Africa

(2012) N. K. Wolzak et al.   JOURNAL OF TROPICAL PEDIATRICS

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

(2012) J. Kleinnijenhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterologous prime-boost regimen adenovector 35-circumsporozoite protein vaccine/recombinant Bacillus Calmette-Guérin expressing the Plasmodium falciparum circumsporozoite induces enhanced long-term memory immunity in BALB/c mice

(2012) Charles Arama et al.   VACCINE

The recombinant tuberculosis vaccine rBCG ΔureC::hly+ induces apoptotic vesicles for improved priming of CD4+ and CD8+ T cells

(2012) Maura Farinacci et al.   VACCINE

Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial

(2012) Isabel Leroux-Roels et al.   VACCINE

Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go?

(2012) Tom H. M. Ottenhoff et al.   PLoS Pathogens

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Floating between the poles of pathology and protection: can we pin down the granuloma in tuberculosis?

(2011) Stephen T Reece et al.   CURRENT OPINION IN MICROBIOLOGY

Early antiretroviral treatment reduces risk of bacille Calmette-Guérin immune reconstitution adenitis

(2011) H. Rabie et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Non-specific effects of BCG?

(2011) P. E. M. Fine et al.   JOURNAL OF INFECTIOUS DISEASES

Recombinant BCG ΔureC hly+ Induces Superior Protection Over Parental BCG by Stimulating a Balanced Combination of Type 1 and Type 17 Cytokine Responses

(2011) Christiane Desel et al.   JOURNAL OF INFECTIOUS DISEASES

Randomized Trial of BCG Vaccination at Birth to Low-Birth-Weight Children: Beneficial Nonspecific Effects in the Neonatal Period?

(2011) Peter Aaby et al.   JOURNAL OF INFECTIOUS DISEASES

A multistage tuberculosis vaccine that confers efficient protection before and after exposure

(2011) Claus Aagaard et al.   NATURE MEDICINE

Small Randomized Trial Among Low–birth-weight Children Receiving Bacillus Calmette-Guéerin Vaccination at First Health Center Contact

(2011) Sofie Biering-Sørensen et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Taking a New Shot At a TB Vaccine

(2011) K. Kupferschmidt   SCIENCE

Improved long-term protection against Mycobacterium tuberculosis Beijing/W in mice after intra-dermal inoculation of recombinant BCG expressing latency associated antigens

(2011) Stephen T. Reece et al.   VACCINE

A recombinant Bacille Calmette–Guérin construct expressing the Plasmodium falciparum circumsporozoite protein enhances dendritic cell activation and primes for circumsporozoite-specific memory cells in BALB/c mice

(2011) Charles Arama et al.   VACCINE

The BCG World Atlas: A Database of Global BCG Vaccination Policies and Practices

(2011) Alice Zwerling et al.   PLOS MEDICINE

The non-specific effects of vaccines

(2010) F. Shann   ARCHIVES OF DISEASE IN CHILDHOOD

Recombinant Mycobacterium bovis BCG as an HIV Vaccine Vector

(2010) Rosamund Chapman et al.   CURRENT HIV RESEARCH

Bacillus Calmette-Guérin treatment of non-muscle invasive bladder cancer

(2010) Richard J Sylvester   INTERNATIONAL JOURNAL OF UROLOGY

CD4+Regulatory T Cells in a Cynomolgus Macaque Model ofMycobacterium tuberculosisInfection

(2010) Angela M. Green et al.   JOURNAL OF INFECTIOUS DISEASES

Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis

(2010) Thomas Dick et al.   MOLECULAR MICROBIOLOGY

A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis

(2010) S. Bertholet et al.   Science Translational Medicine

Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

(2010) Jaap T. van Dissel et al.   VACCINE

Short-term and long-term risk of tuberculosis associated with CD4 cell recovery during antiretroviral therapy in South Africa

(2009) Stephen D Lawn et al.   AIDS

Disseminated bacille Calmette-Guerin disease in HIV-infected South African infants

(2009) AC Hesseling   BULLETIN OF THE WORLD HEALTH ORGANIZATION

ESX/type VII secretion systems and their role in host–pathogen interaction

(2009) Roxane Simeone et al.   CURRENT OPINION IN MICROBIOLOGY

A role for IL-18 in protective immunity againstMycobacterium tuberculosis

(2009) Bianca E. Schneider et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-α/β, IFN-γ, and IFN-λ in host defense

(2009) Shen-Ying Zhang et al.   IMMUNOLOGICAL REVIEWS

Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis

(2009) Ronggai Sun et al.   VACCINE

Endocytosis mechanisms and the cell biology of antigen presentation

(2008) Sven Burgdorf et al.   CURRENT OPINION IN IMMUNOLOGY

Bacillus Calmette–Guérin (BCG) vaccine-induced complications in children treated with highly active antiretroviral therapy

(2008) James J. Nuttall et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

A New Recombinant Bacille Calmette‐Guérin Vaccine Safely Induces Significantly Enhanced Tuberculosis‐Specific Immunity in Human Volunteers

(2008) Daniel F. Hoft et al.   JOURNAL OF INFECTIOUS DISEASES

Role of neutrophils in BCG immunotherapy for bladder cancer

(2008) Mark P. Simons et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Rational design of vaccines against tuberculosis directed by basic immunology

(2007) Stephen T. Reece et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY