The personal touch: strategies toward personalized vaccines and predicting immune responses to them

Measles: the legacy of low vaccine coverage

(2013) M. E. Ramsay   ARCHIVES OF DISEASE IN CHILDHOOD

Prediction and early diagnosis of complex diseases by edge-network

(2013) Xiangtian Yu et al.   BIOINFORMATICS

Predictive markers of safety and immunogenicity of adjuvanted vaccines

(2013) Beatris Mastelic et al.   BIOLOGICALS

Confero: an integrated contrast data and gene set platform for computational analysis and biological interpretation of omics data

(2013) Leandro Hermida et al.   BMC GENOMICS

Vaccine Adjuvants: Key Tools for Innovative Vaccine Design

(2013) Peggy Riese et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Innate Immune Functions of a-Defensins in the Small Intestine

(2013) Charles L. Bevins   DIGESTIVE DISEASES

Antimicrobial peptides and gut microbiota in homeostasis and pathology

(2013) Maureen J. Ostaff et al.   EMBO Molecular Medicine

Gene signatures related to B-cell proliferation predict influenza vaccine-induced antibody response

(2013) Yan Tan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Illuminating the lipidome to advance biomedical research: peptide-based probes of membrane lipids

(2013) Jianmin Gao et al.   Future Medicinal Chemistry

Therapeutic Potential of Fecal Microbiota Transplantation

(2013) Loek P. Smits et al.   GASTROENTEROLOGY

Associations between polymorphisms in the antiviral TRIM genes and measles vaccine immunity

(2013) Inna G. Ovsyannikova et al.   HUMAN IMMUNOLOGY

A genome-wide association study identifies polymorphisms in the HLA-DR region associated with non-response to hepatitis B vaccination in Chinese Han populations

(2013) Liping Pan et al.   HUMAN MOLECULAR GENETICS

Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines

(2013) Gerlinde Obermoser et al.   IMMUNITY

Genetic Variation in IL18R1 and IL18 Genes and Inteferon γ ELISPOT Response to Smallpox Vaccination: An Unexpected Relationship

(2013) Inna G. Ovsyannikova et al.   JOURNAL OF INFECTIOUS DISEASES

Toll-Like Receptors in Antiviral Innate Immunity

(2013) Sandra N. Lester et al.   JOURNAL OF MOLECULAR BIOLOGY

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Application of Machine Learning to Proteomics Data: Classification and Biomarker Identification in Postgenomics Biology

(2013) Anna Louise Swan et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Postgenomics Diagnostics: Metabolomics Approaches to Human Blood Profiling

(2013) Oxana Trifonova et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Genomic Copy Number Variants: Evidence for Association with Antibody Response to Anthrax Vaccine Adsorbed

(2013) Michael I. Falola et al.   PLoS One

Correlation between Human Leukocyte Antigen Class II Alleles and HAI Titers Detected Post-Influenza Vaccination

(2013) Alastair J. Moss et al.   PLoS One

Ex Vivo Analysis of Human Memory B Lymphocytes Specific for A and B Influenza Hemagglutinin by Polychromatic Flow-Cytometry

(2013) Monia Bardelli et al.   PLoS One

Characterization of the Upper Respiratory Tract Microbiomes of Patients with Pandemic H1N1 Influenza

(2013) Bonnie Chaban et al.   PLoS One

Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination

(2013) D. Furman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccinomics, adversomics, and the immune response network theory: Individualized vaccinology in the 21st century

(2013) Gregory A. Poland et al.   SEMINARS IN IMMUNOLOGY

Personalized vaccinology: One size and dose might not fit both sexes

(2013) Sabra L. Klein et al.   VACCINE

Soft truncation thresholding for gene set analysis of RNA-seq data: Application to a vaccine study

(2013) Brooke L. Fridley et al.   Scientific Reports

Diet, Microbiome, and the Intestinal Epithelium: An Essential Triumvirate?

(2013) Javier Rivera Guzman et al.   Biomed Research International

Sex influences immune responses to viruses, and efficacy of prophylaxis and treatments for viral diseases

(2012) Sabra L. Klein   BIOESSAYS

Potential use of inflammation and early immunological event biomarkers in assessing vaccine safety

(2012) Béatris Mastelic et al.   BIOLOGICALS

Rotavirus vaccination: a concise review

(2012) T. Vesikari   CLINICAL MICROBIOLOGY AND INFECTION

Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine adjuvants

(2012) Colleen Olive   Expert Review of Vaccines

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients

(2012) Richard B. Kennedy et al.   HUMAN GENETICS

Genome-wide genetic associations with IFNγ response to smallpox vaccine

(2012) Richard B. Kennedy et al.   HUMAN GENETICS

TLR3 and RIG-I gene variants: Associations with functional effects on receptor expression and responses to measles virus and vaccine in vaccinated infants

(2012) Holly D. Clifford et al.   HUMAN IMMUNOLOGY

Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8+ T Cell Phenotypes

(2012) Evan W. Newell et al.   IMMUNITY

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

(2012) Michael C. Abt et al.   IMMUNITY

Sex affects immunity

(2012) Leesa M. Pennell et al.   JOURNAL OF AUTOIMMUNITY

Prevalence of Streptococci and Increased Polymicrobial Diversity Associated with Cystic Fibrosis Patient Stability

(2012) L. M. Filkins et al.   JOURNAL OF BACTERIOLOGY

Microbiome Diversity in the Bronchial Tracts of Patients with Chronic Obstructive Pulmonary Disease

(2012) R. Cabrera-Rubio et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Sensing of RNA Viruses: a Review of Innate Immune Receptors Involved in Recognizing RNA Virus Invasion

(2012) S. Jensen et al.   JOURNAL OF VIROLOGY

Microbiome complexity and Staphylococcus aureus in chronic rhinosinusitis

(2012) Leah M. Feazel et al.   LARYNGOSCOPE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Characterization of the Viral Microbiome in Patients with Severe Lower Respiratory Tract Infections, Using Metagenomic Sequencing

(2012) Fredrik Lysholm et al.   PLoS One

Deep Sequencing of the Oral Microbiome Reveals Signatures of Periodontal Disease

(2012) Bo Liu et al.   PLoS One

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Multigenic control of measles vaccine immunity mediated by polymorphisms in measles receptor, innate pathway, and cytokine genes

(2012) Richard B. Kennedy et al.   VACCINE

Genome-wide association study of antibody response to smallpox vaccine

(2012) Inna G. Ovsyannikova et al.   VACCINE

Consistency of HLA associations between two independent measles vaccine cohorts: A replication study

(2012) Inna G. Ovsyannikova et al.   VACCINE

A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed

(2012) Nicholas M. Pajewski et al.   VACCINE

Systems Biology in Immunology: A Computational Modeling Perspective

(2011) Ronald N. Germain et al.   Annual Review of Immunology

Systems biology approaches to new vaccine development

(2011) Ann L Oberg et al.   CURRENT OPINION IN IMMUNOLOGY

Genetic variants associated with severe pneumonia in A/H1N1 influenza infection

(2011) J. Zuniga et al.   EUROPEAN RESPIRATORY JOURNAL

The Association of CD46, SLAM and CD209 Cellular Receptor Gene SNPs with Variations in Measles Vaccine-Induced Immune Responses: A Replication Study and Examination of Novel Polymorphisms

(2011) Inna G. Ovsyannikova et al.   HUMAN HEREDITY

A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region

(2011) E. Png et al.   HUMAN MOLECULAR GENETICS

Early Patterns of Gene Expression Correlate With the Humoral Immune Response to Influenza Vaccination in Humans

(2011) Kristine L. Bucasas et al.   JOURNAL OF INFECTIOUS DISEASES

Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82

(2011) I. V. Alymova et al.   JOURNAL OF VIROLOGY

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

The Human Plasma Lipidome

(2011) Oswald Quehenberger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vaccinomics and a New Paradigm for the Development of Preventive Vaccines Against Viral Infections

(2011) Gregory A. Poland et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive immunity to rhinoviruses: sex and age matter

(2011) Melanie L Carroll et al.   RESPIRATORY RESEARCH

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

Cytosolic DNA sensors regulating type I interferon induction

(2011) Sinead E. Keating et al.   TRENDS IN IMMUNOLOGY

Vaccinomics and Personalized Vaccinology: Is Science Leading Us Toward a New Path of Directed Vaccine Development and Discovery?

(2011) Gregory A. Poland et al.   PLoS Pathogens

Transcriptional profiling of vaccine-induced immune responses in humans and non-human primates

(2011) I-Ming Wang et al.   Microbial Biotechnology

Mode of action of adjuvants: Implications for vaccine safety and design

(2010) Béatris Mastelic et al.   BIOLOGICALS

Assessing the human immune system through blood transcriptomics

(2010) Damien Chaussabel et al.   BMC BIOLOGY

Associations between SNPs in candidate immune-relevant genes and rubella antibody Levels: a multigenic assessment

(2010) V SHANE Pankratz et al.   BMC IMMUNOLOGY

Systems Biology: An Approach

(2010) P Kohl et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

New adjuvants for human vaccines

(2010) M Lamine Mbow et al.   CURRENT OPINION IN IMMUNOLOGY

Respective roles of TLR, RIG-I and NLRP3 in influenza virus infection and immunity: impact on vaccine design

(2010) Takeshi Ichinohe   Expert Review of Vaccines

Vaccinomics, predictive vaccinology and the future of vaccine development

(2010) Iana H Haralambieva et al.   Future Microbiology

2′-5′-Oligoadenylate synthetase single-nucleotide polymorphisms and haplotypes are associated with variations in immune responses to rubella vaccine

(2010) Iana H. Haralambieva et al.   HUMAN IMMUNOLOGY

Systems Vaccinology

(2010) Bali Pulendran et al.   IMMUNITY

Phylogenetic and metabolic diversity of bacteria associated with cystic fibrosis

(2010) Adam M Guss et al.   ISME Journal

Immunopotentiation of Trivalent Influenza Vaccine When Given with VAX102, a Recombinant Influenza M2e Vaccine Fused to the TLR5 Ligand Flagellin

(2010) H. Keipp Talbot et al.   PLoS One

Vaccinomics and bioinformatics: Accelerants for the next golden age of vaccinology

(2010) Gregory A. Poland et al.   VACCINE

TLR-based immune adjuvants

(2010) Folkert Steinhagen et al.   VACCINE

RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway

(2009) Yu-Hsin Chiu et al.   CELL

Flow cytometry and the future of vaccine development

(2009) Diane L Bolton et al.   Expert Review of Vaccines

Clear and independent associations of several HLA-DRB1 alleles with differential antibody responses to hepatitis B vaccination in youth

(2009) Yufeng Li et al.   HUMAN GENETICS

Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes

(2009) Inna G. Ovsyannikova et al.   HUMAN GENETICS

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Flu Myths: Dispelling the Myths Associated With Live Attenuated Influenza Vaccine

(2009) Pritish K. Tosh et al.   MAYO CLINIC PROCEEDINGS

Application of pharmacogenomics to vaccines

(2009) Gregory A Poland et al.   PHARMACOGENOMICS

Replication of rubella vaccine population genetic studies: Validation of HLA genotype and humoral response associations

(2009) Inna G. Ovsyannikova et al.   VACCINE

Personalized vaccines: the emerging field of vaccinomics

(2008) Gregory A Poland et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vaccine adjuvants: Current challenges and future approaches

(2008) Jennifer H. Wilson-Welder et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

(2008) Djahida Bouskra et al.   NATURE

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Worlds within worlds: evolution of the vertebrate gut microbiota

(2008) Ruth E. Ley et al.   NATURE REVIEWS MICROBIOLOGY

Human Leukocyte Antigen and Cytokine Receptor Gene Polymorphisms Associated With Heterogeneous Immune Responses to Mumps Viral Vaccine

(2008) I. G. Ovsyannikova et al.   PEDIATRICS

Immunogenetics of seasonal influenza vaccine response

(2008) Gregory A. Poland et al.   VACCINE

Sexual dimorphism of humoral immunity with human vaccines

(2008) Ian Francis Cook   VACCINE

Human Genes and Influenza

(2007) Samira Mubareka et al.   JOURNAL OF INFECTIOUS DISEASES

Evidence for a Heritable Predisposition to Death Due to Influenza

(2007) Frederick S. Albright et al.   JOURNAL OF INFECTIOUS DISEASES