Developments in virus-like particle-based vaccines for HIV

Immunogenicity of HIV Virus-Like Particles in Rhesus Macaques by Intranasal Administration

(2012) Luigi Buonaguro et al.   Clinical and Vaccine Immunology

Single DermaVir Immunization: Dose-Dependent Expansion of Precursor/Memory T Cells against All HIV Antigens in HIV-1 Infected Individuals

(2012) Julianna Lisziewicz et al.   PLoS One

HIV p24 as Scaffold for Presenting Conformational HIV Env Antigens

(2012) Maria Tagliamonte et al.   PLoS One

New Paradigms for HIV/AIDS Vaccine Development

(2011) Louis J. Picker et al.   Annual Review of Medicine

Rational design and optimization of downstream processes of virus particles for biopharmaceutical applications: Current advances

(2011) Tiago Vicente et al.   BIOTECHNOLOGY ADVANCES

Can HIV p24 Be a Suitable Scaffold for Presenting Env Antigens?

(2011) Luigi Buonaguro et al.   Clinical and Vaccine Immunology

Phase 1 Safety and Immunogenicity Testing of DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-like Particles

(2011) Paul A. Goepfert et al.   JOURNAL OF INFECTIOUS DISEASES

H5N1 Virus-Like Particle Vaccine Elicits Cross-Reactive Neutralizing Antibodies That Preferentially Bind to the Oligomeric Form of Influenza Virus Hemagglutinin in Humans

(2011) S. Khurana et al.   JOURNAL OF VIROLOGY

HIV-Gag VLPs presenting trimeric HIV-1 gp140 spikes constitutively expressed in stable double transfected insect cell line

(2011) M. Tagliamonte et al.   VACCINE

Generation of HIV-1 Virus-Like Particles expressing different HIV-1 glycoproteins

(2011) M.L. Visciano et al.   VACCINE

Enhanced Mucosal Immune Responses to HIV Virus-Like Particles Containing a Membrane-Anchored Adjuvant

(2011) E. V. Vassilieva et al.   mBio

Virus-Like Particles as Particulate Vaccines

(2010) Luigi Buonaguro et al.   CURRENT HIV RESEARCH

Antiretroviral therapy and management of HIV infection

(2010) Paul A Volberding et al.   LANCET

Progress towards development of an HIV vaccine: report of the AIDS Vaccine 2009 Conference

(2010) Anna Laura Ross et al.   LANCET INFECTIOUS DISEASES

Multiple tandem copies of conserved gp41 epitopes incorporated in gag virus-like particles elicit systemic and mucosal antibodies in an optimized heterologous vector delivery regimen

(2010) Sumiti Jain et al.   VACCINE

Constitutive expression of HIV-VLPs in stably transfected insect cell line for efficient delivery system

(2010) M. Tagliamonte et al.   VACCINE

A plasmid DNA immunogen expressing fifteen protein antigens and complex virus-like particles (VLP+) mimicking naturally occurring HIV

(2010) Eszter Somogyi et al.   VACCINE

Clinical management of HIV-1 resistance

(2009) Roger Paredes et al.   ANTIVIRAL RESEARCH

X-Ray Structures of the Hexameric Building Block of the HIV Capsid

(2009) Owen Pornillos et al.   CELL

Heterologous prime–boost vaccination

(2009) Shan Lu   CURRENT OPINION IN IMMUNOLOGY

Virus-like particle vaccines and adjuvants: the HPV paradigm

(2009) Franco Maria Buonaguro et al.   Expert Review of Vaccines

Molecular immune signatures of HIV-1 vaccines in human PBMCs

(2009) Alessandro Monaco et al.   FEBS LETTERS

Successes, challenges, and limitations of current antiretroviral therapy in low-income and middle-income countries

(2009) John A Bartlett et al.   LANCET INFECTIOUS DISEASES

Virus-like particle vaccine activates conventional B2 cells and promotes B cell differentiation to IgG2a producing plasma cells

(2009) Sheng Zhang et al.   MOLECULAR IMMUNOLOGY

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

(2009) Johannes F. Scheid et al.   NATURE

High-level expression of the HIV-1 Pr55gag polyprotein in transgenic tobacco chloroplasts

(2009) Nunzia Scotti et al.   PLANTA

Long term adverse effects related to nucleoside reverse transcriptase inhibitors: Clinical impact of mitochondrial toxicity

(2009) Anne Maagaard et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Human immunodeficiency virus-like particles with consensus envelopes elicited broader cell-mediated peripheral and mucosal immune responses than polyvalent and monovalent Env vaccines

(2009) Sean P. McBurney et al.   VACCINE

Influenza vaccines based on virus-like particles

(2009) Sang-Moo Kang et al.   VIRUS RESEARCH

Gene expression profile of peripheral blood mononuclear cells in response to HIV-VLPs stimulation

(2008) Luigi Buonaguro et al.   BMC BIOINFORMATICS

Immunogenic Display of Diverse Peptides on Virus-like Particles of RNA Phage MS2

(2008) David S. Peabody et al.   JOURNAL OF MOLECULAR BIOLOGY

Th2 Polarization in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus (HIV)-Infected Subjects, as Activated by HIV Virus-Like Particles

(2008) L. Buonaguro et al.   JOURNAL OF VIROLOGY

HLA Class I-Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral Load

(2008) C. M. Rousseau et al.   JOURNAL OF VIROLOGY

HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition

(2008) T. Miura et al.   JOURNAL OF VIROLOGY

Incorporation of Membrane-Anchored Flagellin into Influenza Virus-Like Particles Enhances the Breadth of Immune Responses

(2008) B.-Z. Wang et al.   JOURNAL OF VIROLOGY

Human papillomavirus L1 protein expressed in tobacco chloroplasts self-assembles into virus-like particles that are highly immunogenic

(2008) Alicia Fernández-San Millán et al.   PLANT BIOTECHNOLOGY JOURNAL

HIV Vaccine Research: The Way Forward

(2008) A. S. Fauci et al.   SCIENCE

Chimaeric HIV-1 subtype C Gag molecules with large in-frame C-terminal polypeptide fusions form virus-like particles

(2008) Richard J. Halsey et al.   VIRUS RESEARCH