The long-term potential of biodegradable poly(lactideco-glycolide) microparticles as the next-generation vaccine adjuvant

Current Major Cancer Targets for Nanoparticle Systems

(2011) D. Wesselinova   CURRENT CANCER DRUG TARGETS

TLR based therapeutics

(2011) Aisling Dunne et al.   CURRENT OPINION IN PHARMACOLOGY

A comparison of anionic nanoparticles and microparticles as vaccine delivery systems

(2011) Janet Wendorf et al.   Human vaccines & immunotherapeutics

A Trimeric, V2-Deleted HIV-1 Envelope Glycoprotein Vaccine Elicits Potent Neutralizing Antibodies but Limited Breadth of Neutralization in Human Volunteers

(2011) Paul Spearman et al.   JOURNAL OF INFECTIOUS DISEASES

Programming the magnitude and persistence of antibody responses with innate immunity

(2011) Sudhir Pai Kasturi et al.   NATURE

Influenza A/H1N1 MF59-Adjuvanted Vaccine in Preterm and Term Children Aged 6 to 23 Months

(2011) S. Esposito et al.   PEDIATRICS

Biodegradable nanoparticles containing TLR3 or TLR9 agonists together with antigen enhance MHC-restricted presentation of the antigen

(2010) Young-Ran Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses

(2010) Moses O Oyewumi et al.   Expert Review of Vaccines

Combination adjuvants: the next generation of adjuvants?

(2010) George Mutwiri et al.   Expert Review of Vaccines

Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems

(2010) Deepa Mohanan et al.   JOURNAL OF CONTROLLED RELEASE

Human Plasmacytoid Dendritic Cells Phagocytose, Process, and Present Exogenous Particulate Antigen

(2010) J. Tel et al.   JOURNAL OF IMMUNOLOGY

A Two-Stage Strategy for Sterilization of Poly(lactide-co-glycolide) Particles by γ-Irradiation Does Not Impair Their Potency for Vaccine Delivery

(2010) Siddhartha Jain et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The RTS,S malaria vaccine

(2010) Sofia Casares et al.   VACCINE

Surfactant-free Formulation of Poly(Lactic/Glycolic) Acid Nanoparticles Encapsulating Functional Polypeptide: A Technical Note

(2009) Yu-Chao Wang et al.   AAPS PHARMSCITECH

Enhancing the therapeutic efficacy of CpG oligonucleotides using biodegradable microparticles

(2009) Padma Malyala et al.   ADVANCED DRUG DELIVERY REVIEWS

The path to a successful vaccine adjuvant – ‘The long and winding road’

(2009) Derek T. O’Hagan et al.   DRUG DISCOVERY TODAY

AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity

(2009) A. M. Didierlaurent et al.   JOURNAL OF IMMUNOLOGY

Nanoparticle-Delivered Multimeric Soluble CD40L DNA Combined with Toll-Like Receptor Agonists as a Treatment for Melanoma

(2009) Geoffrey W. Stone et al.   PLoS One

Particle Size Determines Activation of the Innate Immune System in the Lung

(2009) M. Samuelsen et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Towards Designer Microparticles: Simultaneous Control of Anisotropy, Shape, and Size

(2009) Srijanani Bhaskar et al.   Small

ISCOMs and ISCOMATRIX™

(2009) Hong-Xiang Sun et al.   VACCINE

Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant

(2008) C. R. Casella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles

(2008) Christian Wischke et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Poly(I:C) coated PLGA microparticles induce dendritic cell maturation

(2008) C WISCHKE et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Stabilization of Tetanus Toxoid Encapsulated in PLGA Microspheres

(2008) Wenlei Jiang et al.   MOLECULAR PHARMACEUTICS

Acidic Microclimate pH Distribution in PLGA Microspheres Monitored by Confocal Laser Scanning Microscopy

(2008) Amy G. Ding et al.   PHARMACEUTICAL RESEARCH

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New horizons in adjuvants for vaccine development

(2008) Steven G. Reed et al.   TRENDS IN IMMUNOLOGY

Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity

(2008) Samar Hamdy et al.   VACCINE

TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses

(2008) Eva Schlosser et al.   VACCINE

Biodegradable polymers as non-viral carriers for plasmid DNA delivery

(2007) Jordy Luten et al.   JOURNAL OF CONTROLLED RELEASE

Nanoimprint lithography based fabrication of shape-specific, enzymatically-triggered smart nanoparticles

(2007) Luz Cristal Glangchai et al.   JOURNAL OF CONTROLLED RELEASE

Characterization of antigens adsorbed to anionic PLG microparticles by XPS and TOF‐SIMS

(2007) James Chesko et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Chemical Degradation of Peptides and Proteins in PLGA: A Review of Reactions and Mechanisms

(2007) M.L. Houchin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES