Melanoma brain metastasis: overview of current management and emerging targeted therapies

BRAF Inhibitors for the Treatment of Metastatic Melanoma: Clinical Trials and Mechanisms of Resistance

(2012) A. M. Alcala et al.   CLINICAL CANCER RESEARCH

Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial

(2012) Gerald S Falchook et al.   LANCET

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

A systematic approach to the management of patients with brain metastases of known or unknown primary site

(2011) Athanassios P. Kyritsis et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Can current prognostic scores reliably guide treatment decisions in patients with brain metastases from malignant melanoma?

(2011) Carsten Nieder et al.   Journal of Cancer Research and Therapeutics

Cancer Immunotherapy Comes of Age

(2011) Suzanne L. Topalian et al.   JOURNAL OF CLINICAL ONCOLOGY

Summary Report on the Graded Prognostic Assessment: An Accurate and Facile Diagnosis-Specific Tool to Estimate Survival for Patients With Brain Metastases

(2011) Paul W. Sperduto et al.   JOURNAL OF CLINICAL ONCOLOGY

Vemurafenib

(2011) Keith. T Flaherty et al.   NATURE REVIEWS DRUG DISCOVERY

Vemurafenib for Melanoma Metastases to the Brain

(2011) Nicole M. Rochet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma

(2011) Caroline Robert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Predictive Factors for the Development of Brain Metastasis in Advanced Unresectable Metastatic Melanoma

(2010) Agop Y. Bedikian et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors

(2010) Alex J. Buckmelter et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

(2010) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

(2010) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase II Trial of Temozolomide and Sorafenib in Advanced Melanoma Patients with or without Brain Metastases

(2009) R. K. Amaravadi et al.   CLINICAL CANCER RESEARCH

Diagnosis-Specific Prognostic Factors, Indexes, and Treatment Outcomes for Patients With Newly Diagnosed Brain Metastases: A Multi-Institutional Analysis of 4,259 Patients

(2009) Paul W. Sperduto et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Randomized Phase II Trial Evaluating Two Paclitaxel and Cisplatin–Containing Chemoradiation Regimens As Adjuvant Therapy in Resected Gastric Cancer (RTOG-0114)

(2009) Gary K. Schwartz et al.   JOURNAL OF CLINICAL ONCOLOGY

Betting on immunotherapy for melanoma

(2009) Mario Sznol   Current Oncology Reports

Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma

(2008) Michael B. Atkins et al.   CANCER

Phase I Safety and Pharmacokinetic Study of CT-011, a Humanized Antibody Interacting with PD-1, in Patients with Advanced Hematologic Malignancies

(2008) R. Berger et al.   CLINICAL CANCER RESEARCH

Phase I/II Study of Ipilimumab for Patients With Metastatic Melanoma

(2008) Jeffrey S. Weber et al.   JOURNAL OF CLINICAL ONCOLOGY

Brain and leptomeningeal metastases from cutaneous melanoma: Survival outcomes based on clinical features

(2008) Jeffrey J. Raizer et al.   NEURO-ONCOLOGY

CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS

(2008) F Stephen Hodi et al.   Nature clinical practice. Oncology