Novel droplet platforms for the detection of disease biomarkers

A biocompatible open-surface droplet manipulation platform for detection of multi-nucleotide polymorphism

(2014) C. J. Huang et al.   LAB ON A CHIP

Microfluidic platforms for biomarker analysis

(2014) Sofia Nahavandi et al.   LAB ON A CHIP

Digital PCR on an integrated self-priming compartmentalization chip

(2014) Qiangyuan Zhu et al.   LAB ON A CHIP

Microfluidic platforms for discovery and detection of molecular biomarkers

(2014) Lien-Yu Hung et al.   Microfluidics and Nanofluidics

The Potential Impact of Droplet Microfluidics in Biology

(2013) Thomas Schneider et al.   ANALYTICAL CHEMISTRY

Topography-assisted electromagnetic platform for blood-to-PCR in a droplet

(2013) Chi-Han Chiou et al.   BIOSENSORS & BIOELECTRONICS

Biomarker Discovery for Heterogeneous Diseases

(2013) G. Wallstrom et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Multiplex Picodroplet Digital PCR to Detect KRAS Mutations in Circulating DNA from the Plasma of Colorectal Cancer Patients

(2013) V. Taly et al.   CLINICAL CHEMISTRY

Highly Sensitive Diagnosis of 43 Monogenic Forms of Diabetes or Obesity Through One-Step PCR-Based Enrichment in Combination With Next-Generation Sequencing

(2013) A. Bonnefond et al.   DIABETES CARE

De novo truncating mutations in ASXL3 are associated with a novel clinical phenotype with similarities to Bohring-Opitz syndrome

(2013) Matthew N Bainbridge et al.   Genome Medicine

Digital Polymerase Chain Reaction in an Array of Femtoliter Polydimethylsiloxane Microreactors

(2012) Yongfan Men et al.   ANALYTICAL CHEMISTRY

Low power sessile droplets actuation via modulated surface acoustic waves

(2012) Michael Baudoin et al.   APPLIED PHYSICS LETTERS

Microfluidic platform for on-demand generation of spatially indexed combinatorial droplets

(2012) Helena Zec et al.   LAB ON A CHIP

Droplet microfluidics for amplification-free genetic detection of single cells

(2012) Tushar D. Rane et al.   LAB ON A CHIP

Digital PCR strategies in the development and analysis of molecular biomarkers for personalized medicine

(2012) Elizabeth Day et al.   METHODS

Application of next generation qPCR and sequencing platforms to mRNA biomarker analysis

(2012) Alison S. Devonshire et al.   METHODS

Digital PCR hits its stride

(2012) Monya Baker   NATURE METHODS

Detecting biomarkers with microdroplet technology

(2012) Valérie Taly et al.   TRENDS IN MOLECULAR MEDICINE

Digital Isothermal Quantification of Nucleic Acids via Simultaneous Chemical Initiation of Recombinase Polymerase Amplification Reactions on SlipChip

(2011) Feng Shen et al.   ANALYTICAL CHEMISTRY

Evaluation of a Droplet Digital Polymerase Chain Reaction Format for DNA Copy Number Quantification

(2011) Leonardo B. Pinheiro et al.   ANALYTICAL CHEMISTRY

Electrophoresis of a Charged Droplet in a Dielectric Liquid for Droplet Actuation

(2011) Do Jin Im et al.   ANALYTICAL CHEMISTRY

Droplet-Based Pyrosequencing Using Digital Microfluidics

(2011) Deborah J. Boles et al.   ANALYTICAL CHEMISTRY

Microfluidics Using Spatially Defined Arrays of Droplets in One, Two, and Three Dimensions

(2011) Rebecca R. Pompano et al.   Annual Review of Analytical Chemistry

Multiplex PCR and Emerging Technologies for the Detection of Respiratory Pathogens

(2011) Angela M. Caliendo   CLINICAL INFECTIOUS DISEASES

Applications of electrowetting-based digital microfluidics in clinical diagnostics

(2011) Michael G Pollack et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Making sense of cancer genomic data

(2011) Lynda Chin et al.   GENES & DEVELOPMENT

Multiplexed Quantification of Nucleic Acids with Large Dynamic Range Using Multivolume Digital RT-PCR on a Rotational SlipChip Tested with HIV and Hepatitis C Viral Load

(2011) Feng Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR

(2011) Qun Zhong et al.   LAB ON A CHIP

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

(2011) Deniz Pekin et al.   LAB ON A CHIP

Megapixel digital PCR

(2011) Kevin A Heyries et al.   NATURE METHODS

Clinical Evaluation of the BD ProbeTec™ Neisseria gonorrhoeae Qx Amplified DNA Assay on the BD Viper™ System With XTR™ Technology

(2011) Barbara Van Der Pol et al.   SEXUALLY TRANSMITTED DISEASES

Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing

(2011) Olivier Harismendy et al.   GENOME BIOLOGY

High-Performance Single Cell Genetic Analysis Using Microfluidic Emulsion Generator Arrays

(2010) Yong Zeng et al.   ANALYTICAL CHEMISTRY

Multiplexed Real-Time Polymerase Chain Reaction on a Digital Microfluidic Platform

(2010) Zhishan Hua et al.   ANALYTICAL CHEMISTRY

Spinning Disk Platform for Microfluidic Digital Polymerase Chain Reaction

(2010) Scott O. Sundberg et al.   ANALYTICAL CHEMISTRY

Nanoliter Multiplex PCR Arrays on a SlipChip

(2010) Feng Shen et al.   ANALYTICAL CHEMISTRY

Microdroplets in Microfluidics: An Evolving Platform for Discoveries in Chemistry and Biology

(2010) Ashleigh B. Theberge et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Droplet microfluidics: recent developments and future applications

(2010) Xavier Casadevall i Solvas et al.   CHEMICAL COMMUNICATIONS

Comparison of Sanger Sequencing, Pyrosequencing, and Melting Curve Analysis for the Detection of KRAS Mutations

(2010) Athanasios C. Tsiatis et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Digital PCR on a SlipChip

(2010) Feng Shen et al.   LAB ON A CHIP

A surface topography assisted droplet manipulation platform for biomarker detection and pathogen identification

(2010) Yi Zhang et al.   LAB ON A CHIP

Ultrasensitive, Multiplexed Detection of Cancer Biomarkers Directly in Serum by Using a Quantum Dot-Based Microfluidic Protein Chip

(2009) Mei Hu et al.   ACS Nano

Detection and Analysis of Low-Abundance Cell-Surface Biomarkers Using Enzymatic Amplification in Microfluidic Droplets

(2009) Haakan N. Joensson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microfluidic Confinement of Single Cells of Bacteria in Small Volumes Initiates High-Density Behavior of Quorum Sensing and Growth and Reveals Its Variability

(2009) James Q. Boedicker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrafast microfluidics using surface acoustic waves

(2009) Leslie Y. Yeo et al.   Biomicrofluidics

A light-induced dielectrophoretic droplet manipulation platform

(2009) Sung-Yong Park et al.   LAB ON A CHIP

SlipChip

(2009) Wenbin Du et al.   LAB ON A CHIP

Fundamentals of magnet-actuated droplet manipulation on an open hydrophobic surface

(2009) Zhicheng Long et al.   LAB ON A CHIP

Microdroplet-based PCR enrichment for large-scale targeted sequencing

(2009) Ryan Tewhey et al.   NATURE BIOTECHNOLOGY

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent developments on ZnO films for acoustic wave based bio-sensing and microfluidic applications: a review

(2009) Y.Q. Fu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Clockwork PCR Including Sample Preparation

(2008) Juergen Pipper et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Leveraging liquid dielectrophoresis for microfluidic applications

(2008) Dipankar Chugh et al.   Biomedical Materials

A palmtop-sized rotary-drive-type biochemical analysis system by magnetic bead handling

(2008) Mitsuhiro Shikida et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

A study of EWOD-driven droplets by PIV investigation

(2008) Hsiang-Wei Lu et al.   LAB ON A CHIP

Development of a digital microfluidic platform for point of care testing

(2008) Ramakrishna Sista et al.   LAB ON A CHIP

Droplet microfluidics

(2008) Shia-Yen Teh et al.   LAB ON A CHIP

Circulating mutant DNA to assess tumor dynamics

(2008) Frank Diehl et al.   NATURE MEDICINE

Integrated circuit/microfluidic chip to programmably trap and move cells and droplets with dielectrophoresis

(2007) Thomas P. Hunt et al.   LAB ON A CHIP

On-chip polymerase chain reaction microdevice employing a magnetic droplet-manipulation system

(2007) Hiroyoshi Tsuchiya et al.   SENSORS AND ACTUATORS B-CHEMICAL