Immune response in chronic obstructive pulmonary disease

Persistence of Lung CD8 T Cell Oligoclonal Expansions upon Smoking Cessation in a Mouse Model of Cigarette Smoke-Induced Emphysema

(2014) G. T. Motz et al.   JOURNAL OF IMMUNOLOGY

Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent

(2014) E. Doz et al.   JOURNAL OF IMMUNOLOGY

T cell depletion protects against alveolar destruction due to chronic cigarette smoke exposure in mice

(2013) Patricia L. Podolin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

What Is Chronic Obstructive Pulmonary Disease Anyway?. Continua, Categories, Cut Points, and Moving beyond Spirometry

(2013) Stephen I. Rennard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CXCL13 Production in B Cells via Toll-like Receptor/Lymphotoxin Receptor Signaling Is Involved in Lymphoid Neogenesis in Chronic Obstructive Pulmonary Disease

(2013) Eleni Litsiou et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

HLA Distribution in COPD Patients

(2013) Rosa Faner et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Autoantibodies in the grocery shop: does quantity matter?

(2013) Jan Damoiseaux   IMMUNOLOGIC RESEARCH

Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling

(2013) Joseph M. D. Rastrick et al.   PLoS One

Lung CD8+ T cells in COPD have increased expression of bacterial TLRs

(2013) Christine M Freeman et al.   RESPIRATORY RESEARCH

High levels of lung resident CD4+CD28null cells in COPD: implications of autoimmunity

(2013) K. Hoetzenecker et al.   WIENER KLINISCHE WOCHENSCHRIFT

Increased incidence of autoimmune markers in patients with combined pulmonary fibrosis and emphysema

(2013) Argyris Tzouvelekis et al.   BMC Pulmonary Medicine

Abnormal Lung Aging in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

(2012) Rosa Faner et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

(2012) Jørgen Vestbo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dendritic Cells in Pathogenesis of COPD

(2012) Masoumeh Ezzati Givi et al.   CURRENT PHARMACEUTICAL DESIGN

Myelin Basic Protein-Specific TCR/HLA-DRB5*01:01 Transgenic Mice Support the Etiologic Role of DRB5*01:01 in Multiple Sclerosis

(2012) J. A. Quandt et al.   JOURNAL OF IMMUNOLOGY

An investigation of the resolution of inflammation (catabasis) in COPD

(2012) Aina Noguera et al.   RESPIRATORY RESEARCH

Treating Human Autoimmunity: Current Practice and Future Prospects

(2012) M. D. Rosenblum et al.   Science Translational Medicine

Immunological mechanisms of allergen-specific immunotherapy

(2011) M. Jutel et al.   ALLERGY

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Role of increased CD8/CD28null T cells and alternative co-stimulatory molecules in chronic obstructive pulmonary disease

(2011) G. Hodge et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The search for autoantibodies against elastin, collagen and decorin in COPD

(2011) C. A. Brandsma et al.   EUROPEAN RESPIRATORY JOURNAL

Evasion of COPD in smokers: at what price?

(2011) Manuel G. Cosio et al.   EUROPEAN RESPIRATORY JOURNAL

Systemic CD4+ and CD8+ T-cell cytokine profiles correlate with GOLD stage in stable COPD

(2011) Marthe S. Paats et al.   EUROPEAN RESPIRATORY JOURNAL

Role of IL-1  and the Nlrp3/caspase-1/IL-1  axis in cigarette smoke-induced pulmonary inflammation and COPD

(2011) N. S. Pauwels et al.   EUROPEAN RESPIRATORY JOURNAL

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

(2011) Hélène Bour-Jordan et al.   IMMUNOLOGICAL REVIEWS

Facing a “Slow-Motion Disaster” — The UN Meeting on Noncommunicable Diseases

(2011) Lisa Rosenbaum et al.   NEW ENGLAND JOURNAL OF MEDICINE

P2X7 Receptor and Caspase 1 Activation Are Central to Airway Inflammation Observed after Exposure to Tobacco Smoke

(2011) Suffwan Eltom et al.   PLoS One

Toll-like receptor expression in smokers with and without COPD

(2011) Ida von Scheele et al.   RESPIRATORY MEDICINE

Increase of Th17 cells in peripheral blood of patients with chronic obstructive pulmonary disease

(2011) María Inés Vargas-Rojas et al.   RESPIRATORY MEDICINE

Meeting Brings Attention But Little Action on Chronic Diseases

(2011) S. Reardon   SCIENCE

Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity

(2011) K. L. Hippen et al.   Science Translational Medicine

Chronic Cigarette Smoke Exposure Generates Pathogenic T Cells Capable of Driving COPD-like Disease in Rag2−/−Mice

(2010) Gregory T. Motz et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Extracellular Adenosine Triphosphate and Chronic Obstructive Pulmonary Disease

(2010) Marek Lommatzsch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Novel Insight into Adaptive Immunity in Chronic Obstructive Pulmonary Disease

(2010) Francesca Polverino et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chronic Obstructive Pulmonary Disease Phenotypes

(2010) MeiLan K. Han et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Anti-Tissue Antibodies Are Related to Lung Function in Chronic Obstructive Pulmonary Disease

(2010) Belén Núñez et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Addressing the Complexity of Chronic Obstructive Pulmonary Disease

(2010) Alvar Agusti et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

P2X7Receptor Signaling in the Pathogenesis of Smoke-Induced Lung Inflammation and Emphysema

(2010) Monica Lucattelli et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Tolerogenic dendritic cells in autoimmune diseases

(2010) Honorio Torres-Aguilar et al.   AUTOIMMUNITY REVIEWS

Antiendothelial Cell Antibodies in Patients With COPD

(2010) Masato Karayama et al.   CHEST

Pulmonary dendritic cells: thinking globally, acting locally: Figure 1.

(2010) Troy D. Randall   JOURNAL OF EXPERIMENTAL MEDICINE

Cytotoxic Potential of Lung CD8+ T Cells Increases with Chronic Obstructive Pulmonary Disease Severity and with In Vitro Stimulation by IL-18 or IL-15

(2010) C. M. Freeman et al.   JOURNAL OF IMMUNOLOGY

Variants in FAM13A are associated with chronic obstructive pulmonary disease

(2010) Michael H Cho et al.   NATURE GENETICS

Antinuclear autoantibodies are more prevalent in COPD in association with low body mass index but not with smoking history

(2010) H. P. J. Bonarius et al.   THORAX

The Natural History of Chronic Airflow Obstruction Revisited

(2009) Robab Kohansal et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Anti–Proline-Glycine-Proline or Antielastin Autoantibodies Are Not Evident in Chronic Inflammatory Lung Disease

(2009) Catherine M. Greene et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Investigating the Natural History of Lung Function

(2009) Robab Kohansal et al.   CHEST

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

Anti-elastin autoantibodies are not present in combined pulmonary fibrosis and emphysema

(2009) V. Cottin et al.   EUROPEAN RESPIRATORY JOURNAL

Identification and clinical association of anti-cytokeratin 18 autoantibody in COPD

(2009) Yung-Bin Kuo et al.   IMMUNOLOGY LETTERS

Chronic obstructive pulmonary disease in non-smokers

(2009) Sundeep S Salvi et al.   LANCET

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

Immunologic Aspects of Chronic Obstructive Pulmonary Disease

(2009) Manuel G. Cosio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lung Myeloid Dendritic Cells Coordinately Induce TH1 and TH17 Responses in Human Emphysema

(2009) M. Shan et al.   Science Translational Medicine

Airway Wall Thickening and Emphysema Show Independent Familial Aggregation in Chronic Obstructive Pulmonary Disease

(2008) Bipen D. Patel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Function-Associated Surface Molecules on Airway Dendritic Cells in Cigarette Smokers

(2008) Kai Bratke et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

COPD: A Pediatric Disease

(2008) Andrew Bush   COPD-Journal of Chronic Obstructive Pulmonary Disease

Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes

(2008) A. L. Putnam et al.   DIABETES

Decreased FOXP3 expression in small airways of smokers with COPD

(2008) S. Isajevs et al.   EUROPEAN RESPIRATORY JOURNAL

CD4+T-regulatory cells: toward therapy for human diseases

(2008) Sarah E. Allan et al.   IMMUNOLOGICAL REVIEWS

An evolutionary history of P2X receptors

(2008) Samuel J. Fountain et al.   Purinergic Signalling

Autoantibodies in Patients with Chronic Obstructive Pulmonary Disease

(2007) Carol A. Feghali-Bostwick et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phenotypic characterisation of T-lymphocytes in COPD: abnormal CD4+CD25+ regulatory T-lymphocyte response to tobacco smoking

(2007) B. Barcelo et al.   EUROPEAN RESPIRATORY JOURNAL