Immunology of stiff person syndrome and other GAD-associated neurological disorders

Novel future therapeutic options in Myasthenia Gravis

(2013) Marinos C. Dalakas   AUTOIMMUNITY REVIEWS

Prevalence of neurologic autoantibodies in cohorts of patients with new and established epilepsy

(2013) Tanja Brenner et al.   EPILEPSIA

Progress and stiff challenges in understanding the role of GAD-antibodies in stiff-person syndrome

(2013) Marinos C. Dalakas   EXPERIMENTAL NEUROLOGY

Monoclonal antibodies to 65kDa glutamate decarboxylase induce epitope specific effects on motor and cognitive functions in rats

(2013) Christiane S Hampe et al.   Orphanet Journal of Rare Diseases

Neuronal Surface and Glutamic Acid Decarboxylase Autoantibodies in Nonparaneoplastic Stiff Person Syndrome

(2013) Thashi Chang et al.   JAMA Neurology

Biologics and other novel approaches as new therapeutic options in myasthenia gravis: a view to the future

(2012) Marinos C. Dalakas   Annals of the New York Academy of Sciences

Stiff-Man Syndrome and Variants

(2012) Andrew McKeon   ARCHIVES OF NEUROLOGY

Autoimmune Epilepsy

(2012) Amy M. L. Quek   ARCHIVES OF NEUROLOGY

Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis

(2012) C. G. Bien et al.   BRAIN

Prevalence and immunological spectrum of temporal lobe epilepsy with glutamic acid decarboxylase antibodies

(2012) M. Falip et al.   EUROPEAN JOURNAL OF NEUROLOGY

Human Stiff person syndrome IgG-containing high-titer anti-GAD65 autoantibodies induce motor dysfunction in rats

(2012) Niels Hansen et al.   EXPERIMENTAL NEUROLOGY

Human IgG directed against amphiphysin induces anxiety behavior in a rat model after intrathecal passive transfer

(2012) Christian Geis et al.   JOURNAL OF NEURAL TRANSMISSION

Glycine receptor antibodies are detected in progressive encephalomyelitis with rigidity and myoclonus (PERM) but not in saccadic oscillations

(2012) Takahiro Iizuka et al.   JOURNAL OF NEUROLOGY

Glycine Receptor Autoimmune Spectrum With Stiff-Man Syndrome Phenotype

(2012) Andrew McKeon et al.   JAMA Neurology

Autoantibodies associated with diseases of the CNS: new developments and future challenges

(2011) Angela Vincent et al.   LANCET NEUROLOGY

Pathological findings in a case of stiff person syndrome with anti-GAD antibodies

(2011) Jonathan Witherick et al.   MOVEMENT DISORDERS

Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia

(2011) Mario U Manto et al.   Orphanet Journal of Rare Diseases

Human Stiff-Person Syndrome IgG Induces Anxious Behavior in Rats

(2011) Christian Geis et al.   PLoS One

Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition

(2010) Christian Geis et al.   BRAIN

Autoantibodies to glutamic acid decarboxylase in patients with epilepsy are associated with low cortical GABA levels

(2010) Charlotte J. Stagg et al.   EPILEPSIA

A critical update on the immunopathogenesis of Stiff Person Syndrome

(2010) Harry Alexopoulos et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Central Nervous System Destruction Mediated by Glutamic Acid Decarboxylase-Specific CD4+ T Cells

(2010) A. R. Burton et al.   JOURNAL OF IMMUNOLOGY

Qualitative and quantitative evidence of anti-glutamic acid decarboxylase-specific intrathecal antibody synthesis in patients with stiff person syndrome

(2010) S. Jarius et al.   JOURNAL OF NEUROIMMUNOLOGY

Antiglycine-receptor encephalomyelitis with rigidity

(2010) N. Mas et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Long-Lived Plasma Cells and Memory B Cells Produce Pathogenic Anti-GAD65 Autoantibodies in Stiff Person Syndrome

(2010) Marta Rizzi et al.   PLoS One

Antibodies to glutamic acid decarboxylase define a form of limbic encephalitis

(2009) Michael P. Malter et al.   ANNALS OF NEUROLOGY

Structural biology of the GAD autoantigen

(2009) Gustavo Fenalti et al.   AUTOIMMUNITY REVIEWS

Stiff person syndrome associated with lower motor neuron disease and infiltration of cytotoxic T cells in the spinal cord

(2009) Trygve Holmøy et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Stiff person syndrome: Advances in pathogenesis and therapeutic interventions

(2009) Marinos C. Dalakas   Current Treatment Options in Neurology

Stiff person syndrome associated anti-amphiphysin antibodies reduce GABA associated [Ca2+]i rise in embryonic motoneurons

(2009) C. Geis et al.   NEUROBIOLOGY OF DISEASE

Increased spontaneous activity of a network of hippocampal neurons in culture caused by suppression of inhibitory potentials mediated by anti-gad antibodies

(2008) Marika Vianello et al.   AUTOIMMUNITY

Stiff, twitchy or wobbly—are GAD antibodies pathogenic?

(2008) Angela Vincent   BRAIN

Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association

(2008) Albert Saiz et al.   BRAIN

Advances in the pathogenesis and treatment of patients with stiff person syndrome

(2008) Marinos C. Dalakas   Current Neurology and Neuroscience Reports

GAD65 IgG autoantibodies in stiff person syndrome: clonality, avidity and persistence

(2008) G. Skorstad et al.   EUROPEAN JOURNAL OF NEUROLOGY

Cerebrospinal fluid T cell responses against glutamic acid decarboxylase 65 in patients with stiff person syndrome

(2008) Gjertrud Skorstad et al.   JOURNAL OF AUTOIMMUNITY

Invited Article: Inhibition of B cell functions: Implications for neurology

(2008) M. C. Dalakas   NEUROLOGY

The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes

(2008) S. Oak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High definition profiling of autoantibodies to glutamic acid decarboxylases GAD65/GAD67 in stiff-person syndrome

(2007) Peter D. Burbelo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS