An underestimated lentivirus model: what can HIV-2 research contribute to the development of an effective HIV-1 vaccine?

Mother‐to‐Child Transmission of HIV‐2 Infection from 1986 to 2007 in the ANRS French Perinatal Cohort EPF‐CO1

(2010) M. Burgard et al.   CLINICAL INFECTIOUS DISEASES

Highly avid, oligoclonal, early-differentiated antigen-specific CD8+ T cells in chronic HIV-2 infection

(2010) Aleksandra Leligdowicz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

HIV-2 CRF01_AB: First Circulating Recombinant Form of HIV-2

(2010) Shiro Ibe et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Microbial Translocation Correlates with the Severity of Both HIV‐1 and HIV‐2 Infections

(2010) Salma Nowroozalizadeh et al.   JOURNAL OF INFECTIOUS DISEASES

Influence of HLA Class I and HLA-KIR Compound Genotypes on HIV-2 Infection and Markers of Disease Progression in a Manjako Community in West Africa

(2010) L.-M. Yindom et al.   JOURNAL OF VIROLOGY

Accelerating HIV vaccine development

(2010) Wayne C. Koff   NATURE

Undetectable plasma viral load predicts normal survival in HIV-2-infected people in a West African village

(2010) Maarten van der Loeff et al.   Retrovirology

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

(2010) T. Zhou et al.   SCIENCE

HIV-2 capsids distinguish high and low virus load patients in a West African community cohort

(2010) Clayton O. Onyango et al.   VACCINE

TRIM5α Modulates Immunodeficiency Virus Control in Rhesus Monkeys

(2010) So-Yon Lim et al.   PLoS Pathogens

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

Good response to lopinavir/ritonavir-containing antiretroviral regimens in antiretroviral-naive HIV-2-infected patients

(2009) Antoine Bénard et al.   AIDS

Molecular Phylogenetics of Nearly Full-Length HIV Type 2 envelope Gene Sequences from West India

(2009) Sushama Jadhav et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

20 Years of HIV‐2 Infection in Portugal: Trends and Changes in Epidemiology

(2009) Emília Valadas et al.   CLINICAL INFECTIOUS DISEASES

AIDS in African Nonhuman Primate Hosts of SIVs: A New Paradigm of SIV Infection

(2009) Ivona Pandrea et al.   CURRENT HIV RESEARCH

Molecular Characterization of a Full-Length Genome of a HIV-2 Isolate From India

(2009) Susmita R Gurjar et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

(2009) Nilu Goonetilleke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clinical Outcomes of Elite Controllers, Viremic Controllers, and Long‐Term Nonprogressors in the US Department of Defense HIV Natural History Study

(2009) Jason F. Okulicz et al.   JOURNAL OF INFECTIOUS DISEASES

Direct Relationship between Virus Load and Systemic Immune Activation in HIV‐2 Infection

(2009) Aleksandra Leligdowicz et al.   JOURNAL OF INFECTIOUS DISEASES

Downregulation of the T-Cell Receptor by Human Immunodeficiency Virus Type 2 Nef Does Not Protect against Disease Progression

(2009) J. Feldmann et al.   JOURNAL OF VIROLOGY

AIDS: lessons learnt and myths dispelled

(2009) Peter Piot et al.   LANCET

Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts

(2009) Donald L Sodora et al.   NATURE MEDICINE

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Dating the Age of the SIV Lineages That Gave Rise to HIV-1 and HIV-2

(2009) Joel O. Wertheim et al.   PLoS Computational Biology

Mortality of HIV-Infected Patients Starting Antiretroviral Therapy in Sub-Saharan Africa: Comparison with HIV-Unrelated Mortality

(2009) Martin W. G. Brinkhof et al.   PLOS MEDICINE

Transcriptional Profiling in Pathogenic and Non-Pathogenic SIV Infections Reveals Significant Distinctions in Kinetics and Tissue Compartmentalization

(2009) Sharon Lederer et al.   PLoS Pathogens

A call for randomized controlled trials of antiretroviral therapy for HIV-2 infection in West Africa

(2008) Geoffrey S Gottlieb et al.   AIDS

Full-Length Genome Characterization of an HIV Type 2 Isolate from India

(2008) C. V. Santhosh et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Polyfunctional T cell responses are a hallmark of HIV-2 infection

(2008) Melody G. Duvall et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Elite control of HIV infection: implications for vaccine design

(2008) BM Baker et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

(2008) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Vpx Is Critical for Reverse Transcription of the Human Immunodeficiency Virus Type 2 Genome in Macrophages

(2008) M. Fujita et al.   JOURNAL OF VIROLOGY

Simian Immunodeficiency Virus SIVagm Dynamics in African Green Monkeys

(2008) I. Pandrea et al.   JOURNAL OF VIROLOGY

Challenges in the development of an HIV-1 vaccine

(2008) Dan H. Barouch   NATURE

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections

(2008) Judith N Mandl et al.   NATURE MEDICINE

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection

(2008) Wayne B Dyer et al.   Retrovirology

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE

HIV-2: the forgotten AIDS virus

(2008) Thushan I. de Silva et al.   TRENDS IN MICROBIOLOGY