Novel expression of Neuropilin 1 on human tumor-infiltrating lymphocytes in colorectal cancer liver metastases

Neuropilin-1-Targeted Gold Nanoparticles Enhance Therapeutic Efficacy of Platinum(IV) Drug for Prostate Cancer Treatment

(2014) Anil Kumar et al.   ACS Nano

Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model

(2014) Lucia Borriello et al.   CANCER LETTERS

Phenotypic alterations, clinical impact and therapeutic potential of regulatory T cells in cancer

(2014) Belal Chaudhary et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes

(2014) Eric E. Paoli et al.   JOURNAL OF CONTROLLED RELEASE

Enhancement of the Tumor Penetration of Monoclonal Antibody by Fusion of a Neuropilin-Targeting Peptide Improves the Antitumor Efficacy

(2014) T.-H. Shin et al.   MOLECULAR CANCER THERAPEUTICS

Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

(2013) Andrea Casazza et al.   CANCER CELL

Neuropilin 1: function and therapeutic potential in cancer

(2013) Belal Chaudhary et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Regulatory T cell subsets in human cancer: are they regulating for or against tumor progression?

(2013) Theresa L. Whiteside   CANCER IMMUNOLOGY IMMUNOTHERAPY

Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer

(2013) Carolyn A Staton et al.   HISTOPATHOLOGY

Prognostic implications of tumor-infiltrating FoxP3+ regulatory T cells and CD8+ cytotoxic T cells in microsatellite-unstable gastric cancers

(2013) Kyung-Ju Kim et al.   HUMAN PATHOLOGY

The VEGF receptor, neuropilin-1, represents a promising novel target for chronic lymphocytic leukemia patients

(2013) Agnieszka Piechnik et al.   INTERNATIONAL JOURNAL OF CANCER

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors

(2013) Aurélien Marabelle et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Memory Helios- FOXP3+ Regulatory T Cells (Tregs) Encompass Induced Tregs That Express Aiolos and Respond to IL-1  by Downregulating Their Suppressor Functions

(2013) C. Raffin et al.   JOURNAL OF IMMUNOLOGY

Highly prevalent colorectal cancer-infiltrating LAP+ Foxp3− T cells exhibit more potent immunosuppressive activity than Foxp3+ regulatory T cells

(2013) M Scurr et al.   Mucosal Immunology

Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis

(2013) Greg M. Delgoffe et al.   NATURE

Potential role of plasmacytoid dendritic cells for FOXP3+ regulatory T cell development in human colorectal cancer and tumor draining lymph node

(2013) Xiao Dong Gai et al.   PATHOLOGY RESEARCH AND PRACTICE

Neuropilin-1 Expression Characterizes T Follicular Helper (Tfh) Cells Activated during B Cell Differentiation in Human Secondary Lymphoid Organs

(2013) Amédée Renand et al.   PLoS One

Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans

(2013) D. Sugiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity

(2013) Mahesh Yadav et al.   Frontiers in Immunology

Neuropilin 1 guides regulatory T cells into VEGF-producing melanoma

(2013) Wiebke Hansen   OncoImmunology

Expression of neuropilin-1 on in vivo induced regulatory T cells

(2013) Christopher J Nirschl et al.   Journal for ImmunoTherapy of Cancer

Pharmacokinetic and Pharmacodynamic Analysis of Circulating Biomarkers of Anti-NRP1, a Novel Antiangiogenesis Agent, in Two Phase I Trials in Patients with Advanced Solid Tumors

(2012) Y. Xin et al.   CLINICAL CANCER RESEARCH

Helios expression in FoxP3+T regulatory cells

(2012) Eyad Elkord et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Induced and natural regulatory T cells in human cancer

(2012) Theresa L. Whiteside et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Neuropilin 1 deficiency on CD4+Foxp3+regulatory T cells impairs mouse melanoma growth

(2012) Wiebke Hansen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+T reg cells

(2012) Jonathan M. Weiss et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

(2012) Mahesh Yadav et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comment on "Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells"

(2012) E. Elkord   JOURNAL OF IMMUNOLOGY

Helios Induces Epigenetic Silencing of Il2 Gene Expression in Regulatory T Cells

(2012) I. Baine et al.   JOURNAL OF IMMUNOLOGY

Phenotypic and Functional Properties of Helios+ Regulatory T Cells

(2012) Daniel J. Zabransky et al.   PLoS One

Tumour Cell Generation of Inducible Regulatory T-Cells in Multiple Myeloma Is Contact-Dependent and Antigen-Presenting Cell-Independent

(2012) Sylvia Feyler et al.   PLoS One

Distribution of regulatory T cells and interaction with dendritic cells in the synovium of rheumatoid arthritis

(2012) XQ E et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs

(2011) Eyad Elkord et al.   CLINICAL IMMUNOLOGY

Establishment and Large-scale Expansion of Minimally cultured “Young” Tumor Infiltrating Lymphocytes for Adoptive Transfer Therapy

(2011) Orit Itzhaki et al.   JOURNAL OF IMMUNOTHERAPY

Neuropilin-1 expression in cancer and development

(2011) Adrian M Jubb et al.   JOURNAL OF PATHOLOGY

Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors

(2011) Derek A. Wainwright et al.   NEURO-ONCOLOGY

Helios Expression Is a Marker of T Cell Activation and Proliferation

(2011) Tatiana Akimova et al.   PLoS One

Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity

(2010) H Jia et al.   BRITISH JOURNAL OF CANCER

Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta

(2010) Yelena Glinka et al.   CARCINOGENESIS

Gene Expression of Neuropilin-1 and Its Receptors, VEGF/Semaphorin 3a, in Normal and Cancer Cells

(2010) Ding Haixia et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Selective Changes in the Immune Profile of Tumor-Draining Lymph Nodes After Different Neoadjuvant Chemoradiation Regimens for Locally Advanced Cervical Cancer

(2010) Alessandra Battaglia et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The Neuroimmune Semaphorin-3A Reduces Inflammation and Progression of Experimental Autoimmune Arthritis

(2010) A. Catalano   JOURNAL OF IMMUNOLOGY

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

(2009) M. Ahmadzadeh et al.   BLOOD

Metastatic tumour cells favour the generation of a tolerogenic milieu in tumour draining lymph node in patients with early cervical cancer

(2009) Alessandra Battaglia et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Neuropilin‐1 is not a marker of human Foxp3+Treg

(2009) Pierre Milpied et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Frequency of human T regulatory cells in peripheral blood is significantly reduced by cryopreservation

(2009) Eyad Elkord   JOURNAL OF IMMUNOLOGICAL METHODS

Neuropilin-1 Expression on Regulatory T Cells Enhances Their Interactions with Dendritic Cells during Antigen Recognition

(2008) Milka Sarris et al.   IMMUNITY

Neuropilin-1 expression identifies a subset of regulatory T cells in human lymph nodes that is modulated by preoperative chemoradiation therapy in cervical cancer

(2007) Alessandra Battaglia et al.   IMMUNOLOGY