MmpL3 a potential new target for development of novel anti-tuberculosis drugs
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
MmpL3 a potential new target for development of novel anti-tuberculosis drugs
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 18, Issue 3, Pages 247-256
Publisher
Informa Healthcare
Online
2013-12-11
DOI
10.1517/14728222.2014.859677
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties
- (2013) E. Jeffrey North et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Insights on how theMycobacterium tuberculosisheme uptake pathway can be used as a drug target
- (2013) Cedric P Owens et al. Future Medicinal Chemistry
- TheMycobacterium tuberculosisSecreted Protein Rv0203 Transfers Heme to Membrane Proteins MmpL3 and MmpL11
- (2013) Cedric P. Owens et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hitting the tuberculosis wall
- (2013) Charlotte Harrison NATURE REVIEWS DRUG DISCOVERY
- Advances in the development of new tuberculosis drugs and treatment regimens
- (2013) Alimuddin Zumla et al. NATURE REVIEWS DRUG DISCOVERY
- Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection
- (2013) Giovanna Poce et al. PLoS One
- Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tuberculosis Targeting MmpL3
- (2013) Modesto J. Remuiñán et al. PLoS One
- Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
- (2013) F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening
- (2012) Sarah A. Stanley et al. ACS Chemical Biology
- SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis
- (2012) Kapil Tahlan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antigen 85C Inhibition Restricts Mycobacterium tuberculosis Growth through Disruption of Cord Factor Biosynthesis
- (2012) Thulasi Warrier et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Targeting Persisters for Tuberculosis Control
- (2012) Ying Zhang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Outwitting Evolution: Fighting Drug-Resistant TB, Malaria, and HIV
- (2012) Daniel E. Goldberg et al. CELL
- MmpL Genes Are Associated with Mycolic Acid Metabolism in Mycobacteria and Corynebacteria
- (2012) Cristian Varela et al. CHEMISTRY & BIOLOGY
- Targeting the mycobacterial envelope for tuberculosis drug development
- (2012) Lorenza Favrot et al. Expert Review of Anti-Infective Therapy
- Mycobacterium tuberculosis Lacking All Mycolic Acid Cyclopropanation Is Viable but Highly Attenuated and Hyperinflammatory in Mice
- (2012) Daniel Barkan et al. INFECTION AND IMMUNITY
- A Common Mechanism of Inhibition of theMycobacterium tuberculosisMycolic Acid Biosynthetic Pathway by Isoxyl and Thiacetazone
- (2012) Anna E. Grzegorzewicz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- New Drugs for the Treatment of Tuberculosis: Needs, Challenges, Promise, and Prospects for the Future
- (2012) Christian Lienhardt et al. JOURNAL OF INFECTIOUS DISEASES
- Drug-Resistant Tuberculosis—Current Dilemmas, Unanswered Questions, Challenges, and Priority Needs
- (2012) Alimuddin Zumla et al. JOURNAL OF INFECTIOUS DISEASES
- Mutations in the essential FAS II β-hydroxyacyl ACP dehydratase complex confer resistance to thiacetazone inMycobacterium tuberculosisandMycobacterium kansasii
- (2012) Juan M. Belardinelli et al. MOLECULAR MICROBIOLOGY
- Infectious disease: TB's revenge
- (2012) Leigh Phillips NATURE
- Transporter targeted in tuberculosis
- (2012) Stewart T Cole Nature Chemical Biology
- Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane
- (2012) Anna E Grzegorzewicz et al. Nature Chemical Biology
- Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors
- (2012) S. M. Batt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Towards understanding the functional diversity of cell wall mycolic acids of Mycobacterium tuberculosis
- (2012) Jan A. Verschoor et al. PROGRESS IN LIPID RESEARCH
- MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212
- (2011) Valentina La Rosa et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Totally Drug-Resistant Tuberculosis in India
- (2011) Z. F. Udwadia et al. CLINICAL INFECTIOUS DISEASES
- Switch or Funnel: How RND-Type Transport Systems Control Periplasmic Metal Homeostasis
- (2011) E.-H. Kim et al. JOURNAL OF BACTERIOLOGY
- Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2′-Oxidase DprE1
- (2011) Claudia Trefzer et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Decaprenylphosphoryl-β-D-Ribose 2′-Epimerase, the Target of Benzothiazinones and Dinitrobenzamides, Is an Essential Enzyme in Mycobacterium smegmatis
- (2011) Paul K. Crellin et al. PLoS One
- Discovery and characterization of a unique mycobacterial heme acquisition system
- (2011) M. V. Tullius et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Decaprenylphosphoryl-β-D-Ribose 2-Epimerase from Mycobacterium tuberculosis is a Magic Drug Target
- (2010) G. Manina et al. CURRENT MEDICINAL CHEMISTRY
- Drugs in Development for Tuberculosis
- (2010) Ann M. Ginsberg DRUGS
- Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern
- (2010) Seppe Vander Beken et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis
- (2010) Neel R Gandhi et al. LANCET
- The mechanisms and consequences of the extra-pulmonary dissemination of Mycobacterium tuberculosis
- (2010) Nitya Krishnan et al. TUBERCULOSIS
- Leads for antitubercular compounds from kinase inhibitor library screens
- (2010) Sophie Magnet et al. TUBERCULOSIS
- Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosis
- (2009) Joel S. Freundlich et al. ChemMedChem
- Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
- (2009) V. Makarov et al. SCIENCE
- High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors
- (2009) Thierry Christophe et al. PLoS Pathogens
- New Anti-Tuberculosis Drugs with Novel Mechanisms of Action
- (2008) Emma Rivers et al. CURRENT MEDICINAL CHEMISTRY
- Bacterial Growth and Cell Division: a Mycobacterial Perspective
- (2008) E. C. Hett et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Disclosure of the mycobacterial outer membrane: Cryo-electron tomography and vitreous sections reveal the lipid bilayer structure
- (2008) C. Hoffmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug
- (2004) Lee Jia et al. BRITISH JOURNAL OF PHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started