Therapeutic targets associated to E-cadherin dysfunction in gastric cancer
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Therapeutic targets associated to E-cadherin dysfunction in gastric cancer
Authors
Keywords
-
Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 17, Issue 10, Pages 1187-1201
Publisher
Informa Healthcare
Online
2013-08-19
DOI
10.1517/14728222.2013.827174
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer
- (2015) Giulia Piazzi et al. Oncotarget
- E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors
- (2013) Gwen Jordaan et al. BMC CANCER
- Circulating microRNAs as biomarkers for early detection of diffuse-type gastric cancer using a mouse model
- (2013) P Rotkrua et al. BRITISH JOURNAL OF CANCER
- MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN
- (2013) Ting-Song Yang et al. Cancer Cell International
- Monoclonal Antibody against the Ectodomain of E-Cadherin (DECMA-1) Suppresses Breast Carcinogenesis: Involvement of the HER/PI3K/Akt/mTOR and IAP Pathways
- (2013) S. M. Brouxhon et al. CLINICAL CANCER RESEARCH
- Genetic Interaction Screens Identify a Role for Hedgehog Signaling inDrosophilaBorder Cell Migration
- (2013) Erika R. Geisbrecht et al. DEVELOPMENTAL DYNAMICS
- E-cadherin-integrin crosstalk in cancer invasion and metastasis
- (2013) M. Canel et al. JOURNAL OF CELL SCIENCE
- Somatic Mutations and Deletions of the E-Cadherin Gene Predict Poor Survival of Patients With Gastric Cancer
- (2013) Giovanni Corso et al. JOURNAL OF CLINICAL ONCOLOGY
- Regulation of adherens junctions by Rho GTPases and p120-catenin
- (2012) Andre Menke et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The prognostic impact of epidermal growth factor receptor in patients with metastatic gastric cancer
- (2012) Akin Atmaca et al. BMC CANCER
- Dishonorable Discharge: The Oncogenic Roles of Cleaved E-Cadherin Fragments
- (2012) J. M. David et al. CANCER RESEARCH
- Impact of Expression of Human Epidermal Growth Factor Receptors EGFR and ERBB2 on Survival in Stage II/III Gastric Cancer
- (2012) M. Terashima et al. CLINICAL CANCER RESEARCH
- Selective DNA demethylation by fusion of TDG with a sequence-specific DNA-binding domain
- (2012) David J. Gregory et al. Epigenetics
- The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC
- (2012) Joana Figueiredo et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- E-cadherin dysfunction in gastric cancer - Cellular consequences, clinical applications and open questions
- (2012) Patrícia Carneiro et al. FEBS LETTERS
- PTEN at a glance
- (2012) Y. Shi et al. JOURNAL OF CELL SCIENCE
- Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation
- (2012) S Radulescu et al. ONCOGENE
- Pharmaceutical therapies to recode nonsense mutations in inherited diseases
- (2012) Hui-Ling Rose Lee et al. PHARMACOLOGY & THERAPEUTICS
- E-Cadherin Destabilization Accounts for the Pathogenicity of Missense Mutations in Hereditary Diffuse Gastric Cancer
- (2012) Joana Simões-Correia et al. PLoS One
- Expression Profiling of Stem Cell-Related Genes in Neoadjuvant-Treated Gastric Cancer: A NOTCH2, GSK3B and β-catenin Gene Signature Predicts Survival
- (2012) Lukas Bauer et al. PLoS One
- EMT as the ultimate survival mechanism of cancer cells
- (2012) Neha Tiwari et al. SEMINARS IN CANCER BIOLOGY
- Cancer syndromes and therapy by stop-codon readthrough
- (2012) Renata Bordeira-Carriço et al. TRENDS IN MOLECULAR MEDICINE
- Wnt Signaling in Cancer
- (2012) P. Polakis Cold Spring Harbor Perspectives in Biology
- Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, a possible precursor lesion of diffuse gastric cancer
- (2011) Ayako Mimata et al. CANCER SCIENCE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Matrix metalloproteinases in tumorigenesis: an evolving paradigm
- (2011) Hui Hua et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Targeted Therapies for Gastric Cancer
- (2011) Jaclyn Yoong et al. DRUGS
- Chronic ataluren (PTC124) treatment of nonsense mutation cystic fibrosis
- (2011) M. Wilschanski et al. EUROPEAN RESPIRATORY JOURNAL
- Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer
- (2011) Shu Shimada et al. GUT
- E-cadherin impairment increases cell survival through Notch-dependent upregulation of Bcl-2
- (2011) António Carlos Ferreira et al. HUMAN MOLECULAR GENETICS
- Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice
- (2011) Zhenyi Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Suppression of E-Cadherin Function Drives the Early Stages of Ras-Induced Squamous Cell Carcinoma through Upregulation of FAK and Src
- (2011) Addy Alt-Holland et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?
- (2011) David P Minde et al. Molecular Cancer
- Adhesion molecule signalling: not always a sticky business
- (2011) Ugo Cavallaro et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- E-cadherin inhibits tumor cell growth by suppressing PI3K/Akt signaling via β-catenin-Egr1-mediated PTEN expression
- (2011) M-T Lau et al. ONCOGENE
- ADP-Ribosylation Factor 6 Mediates E-Cadherin Recovery by Chemical Chaperones
- (2011) Joana Figueiredo et al. PLoS One
- Targeting Src family kinases in anti-cancer therapies: turning promise into triumph
- (2011) Siyuan Zhang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Src/FAK-mediated regulation of E-cadherin as a mechanism for controlling collective cell movement
- (2011) Alan Serrels et al. Cell Adhesion & Migration
- Phosphorylation of Focal Adhesion Kinase at Tyr397 in Gastric Carcinomas and its Clinical Significance
- (2010) I-Rue Lai et al. AMERICAN JOURNAL OF PATHOLOGY
- Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions
- (2010) Chang Xiao et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Ataluren (PTC124) Induces Cystic Fibrosis Transmembrane Conductance Regulator Protein Expression and Activity in Children with Nonsense Mutation Cystic Fibrosis
- (2010) Isabelle Sermet-Gaudelus et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Repairing faulty genes by aminoglycosides: Development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations
- (2010) Igor Nudelman et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Strategies for the Inhibition of Protein Aggregation in Human Diseases
- (2010) Manuela Bartolini et al. CHEMBIOCHEM
- ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER
- (2010) Riccardo Bernasconi et al. CURRENT OPINION IN CELL BIOLOGY
- Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases
- (2010) F. Engin et al. DIABETES OBESITY & METABOLISM
- Snail1 links transcriptional control with epigenetic regulation
- (2010) Gerhard Christofori EMBO JOURNAL
- Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
- (2010) Chrisostomi Gialeli et al. FEBS Journal
- Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer
- (2010) Joo Hyun Park et al. HUMAN PATHOLOGY
- Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides
- (2010) Célia Floquet et al. NUCLEIC ACIDS RESEARCH
- Frequent Deregulations in the Hedgehog Signaling Network and Cross-Talks with the Epidermal Growth Factor Receptor Pathway Involved in Cancer Progression and Targeted Therapies
- (2010) M. Mimeault et al. PHARMACOLOGICAL REVIEWS
- E-Cadherin Deficiency Initiates Gastric Signet-Ring Cell Carcinoma in Mice and Man
- (2009) B. Humar et al. CANCER RESEARCH
- Interaction of E-cadherin and PTEN Regulates Morphogenesis and Growth Arrest in Human Mammary Epithelial Cells
- (2009) M. V. Fournier et al. CANCER RESEARCH
- Epigenetics in cancer
- (2009) S. Sharma et al. CARCINOGENESIS
- Epithelial-Mesenchymal Transitions in Development and Disease
- (2009) Jean Paul Thiery et al. CELL
- Epigenetics and cancer treatment
- (2009) Lasse Sommer Kristensen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- E-cadherin mutations and cell motility: A genotype–phenotype correlation
- (2009) Ana Rita Mateus et al. EXPERIMENTAL CELL RESEARCH
- Quantification of Epigenetic and Genetic 2nd Hits in CDH1 During Hereditary Diffuse Gastric Cancer Syndrome Progression
- (2009) Carla Oliveira et al. GASTROENTEROLOGY
- Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons
- (2009) A. Zilberberg et al. GUT
- Survival prediction of gastric cancer by a seven-microRNA signature
- (2009) X. Li et al. GUT
- Germline CDH1 deletions in hereditary diffuse gastric cancer families
- (2009) C. Oliveira et al. HUMAN MOLECULAR GENETICS
- Using fruitflies to help understand the molecular mechanisms of human hereditary diffuse gastric cancer
- (2009) Joana Caldeira et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Development of Novel Aminoglycoside (NB54) with Reduced Toxicity and Enhanced Suppression of Disease-Causing Premature Stop Mutations
- (2009) Igor Nudelman et al. JOURNAL OF MEDICINAL CHEMISTRY
- Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
- (2009) Pierre Fenaux et al. LANCET ONCOLOGY
- Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis
- (2009) Tetsuya Ueda et al. LANCET ONCOLOGY
- MicroRNA-9 reduces cell invasion and E-cadherin secretion in SK-Hep-1 cell
- (2009) Tan Hao-Xiang et al. MEDICAL ONCOLOGY
- Expression and Clinical Significance of Focal Adhesion Kinase in the Two Distinct Histological Types, Intestinal and Diffuse, of Human Gastric Adenocarcinoma
- (2009) Constantinos T. Giaginis et al. PATHOLOGY & ONCOLOGY RESEARCH
- N-glycan structures: recognition and processing in the ER
- (2009) Markus Aebi et al. TRENDS IN BIOCHEMICAL SCIENCES
- Cadherin-mediated Intercellular Adhesion and Signaling Cascades Involving Small GTPases
- (2009) T. Watanabe et al. Cold Spring Harbor Perspectives in Biology
- Involvement of Members of the Cadherin Superfamily in Cancer
- (2009) G. Berx et al. Cold Spring Harbor Perspectives in Biology
- Cross talk between hedgehog and epithelial–mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers
- (2008) H Ohta et al. BRITISH JOURNAL OF CANCER
- Enhanced Activation of Epidermal Growth Factor Receptor Caused by Tumor-Derived E-Cadherin Mutations
- (2008) A. Bremm et al. CANCER RESEARCH
- Matrix Metalloproteinase 9 Is a Mediator of Epidermal Growth Factor-Dependent E-Cadherin Loss in Ovarian Carcinoma Cells
- (2008) K. D. Cowden Dahl et al. CANCER RESEARCH
- The cell-cell adhesion molecule E-cadherin
- (2008) F. van Roy et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A Phase 1 Pharmacokinetic and Pharmacodynamic Study of the Histone Deacetylase Inhibitor Belinostat in Patients with Advanced Solid Tumors
- (2008) N. L. Steele et al. CLINICAL CANCER RESEARCH
- The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
- (2008) S.-M. Park et al. GENES & DEVELOPMENT
- Unglycosylation at Asn-633 made extracellular domain of E-cadherin folded incorrectly and arrested in endoplasmic reticulum, then sequentially degraded by ERAD
- (2008) Feng Zhou et al. GLYCOCONJUGATE JOURNAL
- Endoplasmic reticulum quality control: a new mechanism of E-cadherin regulation and its implication in cancer
- (2008) J. Simoes-Correia et al. HUMAN MOLECULAR GENETICS
- The Ectodomain Shedding of E-cadherin by ADAM15 Supports ErbB Receptor Activation
- (2008) Abdo J. Najy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2
- (2008) Manav Korpal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanisms and sequelae of E-cadherin silencing in hereditary diffuse gastric cancer
- (2008) M Barber et al. JOURNAL OF PATHOLOGY
- Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial
- (2008) Eitan Kerem et al. LANCET
- Cadherins in development and cancer
- (2008) Marc P. Stemmler Molecular BioSystems
- Chromatin, cancer and drug therapies
- (2008) Connie C. Cortez et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
- (2008) Philip A. Gregory et al. NATURE CELL BIOLOGY
- One step at a time: endoplasmic reticulum-associated degradation
- (2008) Shruthi S. Vembar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cadherins and cancer: how does cadherin dysfunction promote tumor progression?
- (2008) A Jeanes et al. ONCOGENE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now