Novel therapeutic targets for nonalcoholic fatty liver disease

Nonalcoholic Fatty Liver Disease: Current Issues and Novel Treatment Approaches

(2013) Romina Lomonaco et al.   DRUGS

Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease

(2012) A. Zarrinpar et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Microparticles: major transport vehicles for distinct microRNAs in circulation

(2012) P. Diehl et al.   CARDIOVASCULAR RESEARCH

Circulating Microparticles as Disease-Specific Biomarkers of Severity of Inflammation in Patients With Hepatitis C or Nonalcoholic Steatohepatitis

(2012) Miroslaw Kornek et al.   GASTROENTEROLOGY

Abnormal Plasma Microparticles Impair Vasoconstrictor Responses in Patients With Cirrhosis

(2012) Pierre–Emmanuel Rautou et al.   GASTROENTEROLOGY

NASH is an Infl ammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications

(2012) Geoffrey C. Farrell et al.   Gut and Liver

Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

(2012) Kouichi Miura et al.   HEPATOLOGY

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

(2012) Jan Petrasek et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathophysiology guided treatment of nonalcoholic steatohepatitis

(2012) Tuyet A T Nguyen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Inflammasomes in liver diseases

(2012) Gyongyi Szabo et al.   JOURNAL OF HEPATOLOGY

Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans

(2012) Christopher E. Ramsden et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Microparticles, Vascular Function, and Atherothrombosis

(2011) Pierre-Emmanuel Rautou et al.   CIRCULATION RESEARCH

Nuclear Receptors as New Perspective for the Management of Liver Diseases

(2011) Michael Trauner et al.   GASTROENTEROLOGY

Low-dose steroids for septic shock and severe sepsis: the use of Bayesian statistics to resolve clinical trial controversies

(2011) Andre C. Kalil et al.   INTENSIVE CARE MEDICINE

Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis

(2011) Helen M. Parker et al.   JOURNAL OF HEPATOLOGY

Microparticles: a critical component in the nexus between inflammation, immunity, and thrombosis

(2011) Olivier Morel et al.   Seminars in Immunopathology

Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

(2011) Michal Ganz   WORLD JOURNAL OF GASTROENTEROLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Bile Acids as Regulators of Hepatic Lipid and Glucose Metabolism

(2010) Michael Trauner et al.   DIGESTIVE DISEASES

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

(2010) Kouichi Miura et al.   GASTROENTEROLOGY

Bile acid sequestrants improve glycemic control in type 2 diabetes: A proposed mechanism implicating glucagon-like peptide 1 release

(2010) Alan F. Hofmann   HEPATOLOGY

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Novel Insights into the Pathophysiology of Nonalcoholic Fatty Liver Disease

(2010) Ariel Feldstein   SEMINARS IN LIVER DISEASE

Enhancement in liver SREBP-1c/PPAR-α ratio and steatosis in obese patients: Correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion

(2009) Paulina Pettinelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures

(2009) M. Prokopi et al.   BLOOD

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice

(2009) Astrid Spruss et al.   HEPATOLOGY

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

Therapeutic approach to regulate innate immune response by Toll-like receptor 4 antagonist E5564 in rats with D-galactosamine-induced acute severe liver injury

(2009) Toshiyuki Kitazawa et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Transfer of MicroRNAs by Embryonic Stem Cell Microvesicles

(2009) Alex Yuan et al.   PLoS One

Incretin and islet hormonal responses to fat and protein ingestion in healthy men

(2008) Richard D. Carr et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Efficacy and Safety of Colesevelam in Patients With Type 2 Diabetes Mellitus and Inadequate Glycemic Control Receiving Insulin-Based Therapy

(2008) Ronald B. Goldberg   ARCHIVES OF INTERNAL MEDICINE

Colesevelam Hydrochloride Therapy in Patients With Type 2 Diabetes Mellitus Treated With Metformin

(2008) Harold E. Bays et al.   ARCHIVES OF INTERNAL MEDICINE

Colesevelam HCl Improves Glycemic Control and Reduces LDL Cholesterol in Patients With Inadequately Controlled Type 2 Diabetes on Sulfonylurea-Based Therapy

(2008) V. A. Fonseca et al.   DIABETES CARE

Liver Cell–Derived Microparticles Activate Hedgehog Signaling and Alter Gene Expression in Hepatic Endothelial Cells

(2008) Rafal P. Witek et al.   GASTROENTEROLOGY

Toll‐like receptors and adaptor molecules in liver disease: Update

(2008) Ekihiro Seki et al.   HEPATOLOGY

Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles

(2008) Danielle B. Peterson et al.   PROTEOMICS