Targeting p27Kip1protein: its relevance in the therapy of human cancer

SRC: A Century of Science Brought to the Clinic

(2015) Alexey Aleshin et al.   NEOPLASIA

Increased expression of p27 is associated with the cisplatin resistance in gastric cancer cell line YCC-3

(2010) Tuong Vy Thi Le et al.   ARCHIVES OF PHARMACAL RESEARCH

CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells

(2010) Ryutaro Kajihara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA and proliferation control in chronic lymphocytic leukemia: functional relationship between miR-221/222 cluster and p27

(2010) M. Frenquelli et al.   BLOOD

Tumor suppressor p27Kip1 undergoes endolysosomal degradation through its interaction with sorting nexin 6

(2010) José J. Fuster et al.   FASEB JOURNAL

p27kip1 Controls Cell Morphology and Motility by Regulating Microtubule-Dependent Lipid Raft Recycling

(2010) B. Belletti et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors

(2010) Sara Molatore et al.   Molecular Cancer

A Pumilio-induced RNA structure switch in p27-3′ UTR controls miR-221 and miR-222 accessibility

(2010) Martijn Kedde et al.   NATURE CELL BIOLOGY

Discrimination of multiple primary lung cancers from intrapulmonary metastasis based on the expression of four cancer-related proteins

(2009) Kenji Ono et al.   CANCER

p27Kip1 in Stage III Colon Cancer: Implications for Outcome following Adjuvant Chemotherapy in Cancer and Leukemia Group B Protocol 89803

(2009) M. M. Bertagnolli et al.   CLINICAL CANCER RESEARCH

Interaction of Molecular Markers and Physical Activity on Mortality in Patients with Colon Cancer

(2009) J. A. Meyerhardt et al.   CLINICAL CANCER RESEARCH

Combined Src and Aromatase Inhibition Impairs Human Breast Cancer Growth In vivo and Bypass Pathways Are Activated in AZD0530-Resistant Tumors

(2009) Y. Chen et al.   CLINICAL CANCER RESEARCH

Pin1 Catalyzes Conformational Changes of Thr-187 in p27Kip1and Mediates Its Stability through a Polyubiquitination Process

(2009) Wei Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of p21waf1/cip1, p27kip1, p63 and Androgen Receptor in Low and High Gleason Score Prostate Cancer

(2009) Imre Romics et al.   PATHOLOGY & ONCOLOGY RESEARCH

RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility

(2009) M. D. Larrea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels

(2008) Daniele Baiz et al.   BIOCHIMIE

Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer

(2008) Dan D. Hershko   CANCER

Argyrin A Reveals a Critical Role for the Tumor Suppressor Protein p27kip1 in Mediating Antitumor Activities in Response to Proteasome Inhibition

(2008) Irina Nickeleit et al.   CANCER CELL

Imatinib Mesylate Induces Quiescence in Gastrointestinal Stromal Tumor Cells through the CDH1-SKP2-p27Kip1Signaling Axis

(2008) Ying Liu et al.   CANCER RESEARCH

Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade

(2008) R. Z. Orlowski et al.   CLINICAL CANCER RESEARCH

Cytoplasmic Sequestration of p27 via AKT Phosphorylation in Renal Cell Carcinoma

(2008) J. Kim et al.   CLINICAL CANCER RESEARCH

MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1

(2008) Tyler E. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of p27Kip1 Regulates Assembly and Activation of Cyclin D1-Cdk4

(2008) M. D. Larrea et al.   MOLECULAR AND CELLULAR BIOLOGY

p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis

(2008) M. Schiappacassi et al.   MOLECULAR CANCER THERAPEUTICS

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

(2008) F Fornari et al.   ONCOGENE