Malaria: an update on current chemotherapy

Treatment of Suspected Hyper-Reactive Malarial Splenomegaly (HMS) in Pregnancy with Mefloquine

(2014) Juthamas Jaroensuk et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Mefloquine safety and tolerability in pregnancy: a systematic literature review

(2014) Raquel González et al.   MALARIA JOURNAL

Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort

(2014) Dominic Mosha et al.   MALARIA JOURNAL

A morphometric and histological study of placental malaria shows significant changes to villous architecture in both Plasmodium falciparum and Plasmodium vivax infection

(2014) Sethawud Chaikitgosiyakul et al.   MALARIA JOURNAL

Efficacy of Two versus Three-Day Regimens of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Military Personnel in Northern Cambodia: An Open-Label Randomized Trial

(2014) Chanthap Lon et al.   PLoS One

Effectiveness of artesunate-amodiaquinevs. artemether-lumefantrine for the treatment of uncomplicatedfalciparummalaria in Nanoro, Burkina Faso: a non-inferiority randomised trial

(2014) Halidou Tinto et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Malaria prevention in the pregnant traveller: A review

(2014) Louise Roggelin et al.   Travel Medicine and Infectious Disease

Effectiveness of Artemether/Lumefantrine for the Treatment of Uncomplicated Plasmodium vivax and P. falciparum Malaria in Young Children in Papua New Guinea

(2013) Nicolas Senn et al.   CLINICAL INFECTIOUS DISEASES

American Society for Apheresis Guidelines Support Use of Red Cell Exchange Transfusion for Severe Malaria With High Parasitemia

(2013) B. H. Shaz et al.   CLINICAL INFECTIOUS DISEASES

Exchange Transfusion for Severe Malaria: Evidence Base and Literature Review

(2013) K. R. Tan et al.   CLINICAL INFECTIOUS DISEASES

Human Infections and Detection of Plasmodium knowlesi

(2013) B. Singh et al.   CLINICAL MICROBIOLOGY REVIEWS

Artemether and lumefantrine for the treatment of uncomplicatedPlasmodium falciparummalaria in sub-Saharan Africa

(2013) Bernhards Ogutu   EXPERT OPINION ON PHARMACOTHERAPY

Use of artemether–lumefantrine to treat malaria during pregnancy: what do we know and need to know?

(2013) Theonest K Mutabingwa et al.   Expert Review of Anti-Infective Therapy

Intermittent Preventive Therapy for Malaria During Pregnancy Using 2 vs 3 or More Doses of Sulfadoxine-Pyrimethamine and Risk of Low Birth Weight in Africa

(2013) Kassoum Kayentao et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Delayed Hemolysis After Treatment With Parenteral Artesunate in African Children With Severe Malaria—A Double-center Prospective Study

(2013) Thierry Rolling et al.   JOURNAL OF INFECTIOUS DISEASES

Randomized Controlled Trial of Levamisole Hydrochloride as Adjunctive Therapy in Severe Falciparum Malaria With High Parasitemia

(2013) Richard J. Maude et al.   JOURNAL OF INFECTIOUS DISEASES

A Randomized Comparison of Dihydroartemisinin-Piperaquine and Artesunate-Amodiaquine Combined With Primaquine for Radical Treatment of Vivax Malaria in Sumatera, Indonesia

(2013) A. P. Pasaribu et al.   JOURNAL OF INFECTIOUS DISEASES

Gametocyte Dynamics and the Role of Drugs in Reducing the Transmission Potential of Plasmodium vivax

(2013) Nicholas M. Douglas et al.   JOURNAL OF INFECTIOUS DISEASES

Artemisinin therapy and severe delayed haemolysis

(2013) Joseph N Jarvis et al.   LANCET

Malaria

(2013) Nicholas J White et al.   LANCET

Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial

(2013) Alice C Eziefula et al.   LANCET INFECTIOUS DISEASES

Manual blood exchange transfusion does not significantly contribute to parasite clearance in artesunate-treated individuals with imported severe Plasmodium falciparum malaria

(2013) Annemarie R Kreeftmeijer-Vegter et al.   MALARIA JOURNAL

Comparative safety of artemether-lumefantrine and other artemisinin-based combinations in children: a systematic review

(2013) Oluwaseun Egunsola et al.   MALARIA JOURNAL

Susceptibility of human Plasmodium knowlesi infections to anti-malarials

(2013) Farrah A Fatih et al.   MALARIA JOURNAL

Artemisinin-naphthoquine combination versus chloroquine-primaquine to treat vivax malaria: an open-label randomized and non-inferiority trial in Yunnan Province, China

(2013) Hui Liu et al.   MALARIA JOURNAL

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

In Vivo Efficacy of Artemether-Lumefantrine and Chloroquine against Plasmodium vivax: A Randomized Open Label Trial in Central Ethiopia

(2013) Jimee Hwang et al.   PLoS One

Timing of Malaria Infection during Pregnancy Has Characteristic Maternal, Infant and Placental Outcomes

(2013) Linda Kalilani-Phiri et al.   PLoS One

Efficacy and Safety of Dihydroartemisinin-Piperaquine for Treatment of Plasmodium vivax Malaria in Endemic Countries: Meta-Analysis of Randomized Controlled Studies

(2013) Cho Naing et al.   PLoS One

Factors Affecting the Delivery, Access, and Use of Interventions to Prevent Malaria in Pregnancy in Sub-Saharan Africa: A Systematic Review and Meta-Analysis

(2013) Jenny Hill et al.   PLOS MEDICINE

Pharmacokinetics of Piperaquine in Pregnant Women in Sudan with Uncomplicated Plasmodium falciparum Malaria

(2012) Ishag Adam et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Randomized, Prospective, Three-Arm Study to Confirm the Auditory Safety and Efficacy of Artemether-Lumefantrine in Colombian Patients with Uncomplicated Plasmodium falciparum Malaria

(2012) Gabriel Carrasquilla et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Inadequate Efficacy of a New Formulation of Fosmidomycin-Clindamycin Combination in Mozambican Children Less than Three Years Old with Uncomplicated Plasmodium falciparum Malaria

(2012) Miguel Lanaspa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of Dihydroartemisinin and Piperaquine in Pregnant and Nonpregnant Women with Uncomplicated Malaria

(2012) Joel Tarning et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetic and Pharmacodynamic Modeling of Amodiaquine and Desethylamodiaquine in Women with Plasmodium vivax Malaria during and after Pregnancy

(2012) Joel Tarning et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Artemisinin-Naphthoquine Combination Therapy for Uncomplicated Pediatric Malaria: a Tolerability, Safety, and Preliminary Efficacy Study

(2012) John Benjamin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy of Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010

(2012) R. Leang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Randomized, Open-Label Trial of Primaquine against Vivax Malaria Relapse in Indonesia

(2012) Inge Sutanto et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Artemisinin-Naphthoquine Combination Therapy for Uncomplicated Pediatric Malaria: a Pharmacokinetic Study

(2012) Kevin T. Batty et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pregnancy and Fetal Outcomes After Exposure to Mefloquine in the Pre- and Periconception Period and During Pregnancy

(2012) P. Schlagenhauf et al.   CLINICAL INFECTIOUS DISEASES

A Prospective Comparative Study of Knowlesi, Falciparum, and Vivax Malaria in Sabah, Malaysia: High Proportion With Severe Disease From Plasmodium Knowlesi and Plasmodium Vivax But No Mortality With Early Referral and Artesunate Therapy

(2012) Bridget E. Barber et al.   CLINICAL INFECTIOUS DISEASES

Emerging drugs for malaria

(2012) Serena Tschan et al.   EXPERT OPINION ON EMERGING DRUGS

Intermittent preventive treatment of malaria in pregnant women and infants: making best use of the available evidence

(2012) Azucena Bardají et al.   EXPERT OPINION ON PHARMACOTHERAPY

Small molecule anti-malarial patents: a review (January 2010 – June 2011)

(2012) Katarina L Svennas et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Coartem®: a decade of patient-centric malaria management

(2012) Kamal Hamed et al.   Expert Review of Anti-Infective Therapy

Efficacy of artemether-lumefantrine as a treatment for uncomplicated Plasmodium vivax malaria in eastern Sudan

(2012) Tajeldin M Abdallah et al.   MALARIA JOURNAL

Therapeutic efficacy of artemether-lumefantrine combination in the treatment of uncomplicated malaria among children under five years of age in three ecological zones in Ghana

(2012) Benjamin Abuaku et al.   MALARIA JOURNAL

Pharmacovigilance of artemether-lumefantrine in pregnant women followed until delivery in Rwanda

(2012) Stephen Rulisa et al.   MALARIA JOURNAL

Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial

(2012) Atis Muehlenbachs et al.   MALARIA JOURNAL

Multiple treatment comparisons in a series of anti-malarial trials with an ordinal primary outcome and repeated treatment evaluations

(2012) Solange Youdom et al.   MALARIA JOURNAL

Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixed-species malaria in Gabon

(2012) Ghyslain Mombo-Ngoma et al.   MALARIA JOURNAL

Clinical tolerability of artesunate-amodiaquine versus comparator treatments for uncomplicated falciparum malaria: an individual-patient analysis of eight randomized controlled trials in sub-Saharan Africa

(2012) Julien Zwang et al.   MALARIA JOURNAL

Clindamycin plus quinine for treating uncomplicated falciparum malaria: a systematic review and meta-analysis

(2012) Charles O Obonyo et al.   MALARIA JOURNAL

Therapy of uncomplicated falciparum malaria in Europe: MALTHER – a prospective observational multicentre study

(2012) Olivier Bouchaud et al.   MALARIA JOURNAL

A systematic review of the safety and efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria during pregnancy

(2012) Christine Manyando et al.   MALARIA JOURNAL

Pyronaridine-artesunate granules versus artemether-lumefantrine crushed tablets in children with Plasmodium falciparum malaria: a randomized controlled trial

(2012) Kassoum Kayentao et al.   MALARIA JOURNAL

Efficacy of fixed-dose combination artesunate-amodiaquine versus artemether-lumefantrine for uncomplicated childhood Plasmodium falciparum malaria in Democratic Republic of Congo: a randomized non-inferiority trial

(2012) Emmanuelle Espié et al.   MALARIA JOURNAL

Open-label trial of three dosage regimens of fixeddose combination of artemisinin and naphthoquine for treating uncomplicated falciparum malaria in calabar, Nigeria

(2012) Martin M Meremikwu et al.   MALARIA JOURNAL

Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common

(2012) Nicholas J White et al.   MALARIA JOURNAL

Efficacy and safety of artemisinin-naphthoquine versus dihydroartemisinin-piperaquine in adult patients with uncomplicated malaria: a multi-centre study in Indonesia

(2012) Emiliana Tjitra et al.   MALARIA JOURNAL

Population pharmacokinetics of Artemether and dihydroartemisinin in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda

(2012) Joel Tarning et al.   MALARIA JOURNAL

Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium

(2012) Annemarie R Kreeftmeijer-Vegter et al.   MALARIA JOURNAL

Open-label trial with artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria three years after its broad introduction in Jimma Zone, Ethiopia

(2012) Teferi Eshetu et al.   MALARIA JOURNAL

Pyronaridine–Artesunate versus Mefloquine plus Artesunate for Malaria

(2012) Ronnatrai Rueangweerayut et al.   NEW ENGLAND JOURNAL OF MEDICINE

Access to Artemisinin-Combination Therapy (ACT) and other Anti-Malarials: National Policy and Markets in Sierra Leone

(2012) John H. Amuasi et al.   PLoS One

A pharmacokinetic approach to assess artemisinin–naphthoquine combination therapy for uncomplicated pediatric malaria

(2012) Rong Liu et al.   Expert Review of Clinical Pharmacology

MALARIA IN CHILDREN

(2012) Richard-Fabian Schumacher et al.   Mediterranean Journal of Hematology and Infectious Diseases

Confirmed Vivax Resistance to Chloroquine and Effectiveness of Artemether-Lumefantrine for the Treatment of Vivax Malaria in Ethiopia

(2011) Ambachew M. Yohannes et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Therapeutic Efficacy and Effects of Artemether-Lumefantrine and Artesunate-Amodiaquine Coformulated or Copackaged on Malaria-Associated Anemia in Children with Uncomplicated Plasmodium falciparum Malaria in Southwest Nigeria

(2011) Grace O. Gbotosho et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Efficacy and Safety of Artemether-Lumefantrine in the Treatment of Acute, Uncomplicated Plasmodium falciparum Malaria: A Pooled Analysis

(2011) Michael Makanga et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Pharmacokinetics of Dihydroartemisinin and Piperaquine in Pregnant and Nonpregnant Women with Uncomplicated Falciparum Malaria

(2011) Marcus J. Rijken et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of Amodiaquine and Desethylamodiaquine in Pregnant and Postpartum Women with Plasmodium vivax Malaria

(2011) Marcus J. Rijken et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of artemisinins on reticulocyte count and relationship to possible embryotoxicity in confirmed and unconfirmed malarial patients

(2011) Robert L. Clark   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects

(2011) Rose McGready et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Dihydroartemisinin-Piperaquine Versus Chloroquine in the Treatment of Plasmodium vivax Malaria in Thailand: A Randomized Controlled Trial

(2011) A. P. Phyo et al.   CLINICAL INFECTIOUS DISEASES

Malaria treatment and prophylaxis in endemic and nonendemic countries: evidence on strategies and their cost–effectiveness

(2011) Michèle van Vugt et al.   Future Microbiology

Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: a population-based study

(2011) R McGready et al.   LANCET INFECTIOUS DISEASES

Treatment of imported severe malaria with artesunate instead of quinine - more evidence needed?

(2011) Jakob P Cramer et al.   MALARIA JOURNAL

Patterns of anti-malarial drug treatment among pregnant women in Uganda

(2011) Laura R Sangaré et al.   MALARIA JOURNAL

Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria

(2011) Carrie A Morris et al.   MALARIA JOURNAL

Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children

(2011) Michael Nambozi et al.   MALARIA JOURNAL

Pyronaridine-Artesunate versus Chloroquine in Patients with Acute Plasmodium vivax Malaria: A Randomized, Double-Blind, Non-Inferiority Trial

(2011) Yi Poravuth et al.   PLoS One

Artesunate/mefloquine paediatric formulation vs. artemether/lumefantrine for the treatment of uncomplicated Plasmodium falciparum in Anonkoua kouté, Côte d’Ivoire

(2011) Offianan A. Toure et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

A Head-to-Head Comparison of Four Artemisinin-Based Combinations for Treating Uncomplicated Malaria in African Children: A Randomized Trial

(2011)   PLOS MEDICINE

Increased Risk of Early Vomiting among Infants and Young Children Treated with Dihydroartemisinin-Piperaquine Compared with Artemether-Lumefantrine for Uncomplicated Malaria

(2010) Darren Creek et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A Randomized Trial of Artesunate Mefloquine versus Artemether Lumefantrine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Senegalese Children

(2010) Babacar Faye et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Pharmacokinetics of Chloroquine and Monodesethylchloroquine in Pregnancy

(2010) H. A. Karunajeewa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Current knowledge and challenges of antimalarial drugs for treatment and prevention in pregnancy

(2010) Esperança Sevene et al.   EXPERT OPINION ON PHARMACOTHERAPY

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

(2010) Arjen M Dondorp et al.   LANCET

Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial

(2010) Antoinette K Tshefu et al.   LANCET

Artemisinin combination therapy for vivax malaria

(2010) Nicholas M Douglas et al.   LANCET INFECTIOUS DISEASES

Efficacy and safety of artemether–lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: an open-label, randomised, non-inferiority trial

(2010) Patrice Piola et al.   LANCET INFECTIOUS DISEASES

Anti-malarial market and policy surveys in sub-Saharan Africa

(2010) Graciela Diap et al.   MALARIA JOURNAL

Safety of artemether-lumefantrine in pregnant women with malaria: results of a prospective cohort study in Zambia

(2010) Christine Manyando et al.   MALARIA JOURNAL

Early variations in Plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance

(2010) Obaro S Michael et al.   MALARIA JOURNAL

Dihydroartemisinin-piperaquine versus chloroquine to treat vivax malaria in Afghanistan: an open randomized, non-inferiority, trial

(2010) Ghulam Awab et al.   MALARIA JOURNAL

The position of mefloquine as a 21st century malaria chemoprophylaxis

(2010) Patricia Schlagenhauf et al.   MALARIA JOURNAL

An Open-Label, Randomised Study of Dihydroartemisinin-Piperaquine Versus Artesunate-Mefloquine for Falciparum Malaria in Asia

(2010) Neena Valecha et al.   PLoS One

Toxicokinetic and toxicodynamic (TK/TD) evaluation to determine and predict the neurotoxicity of artemisinins

(2010) Qigui Li et al.   TOXICOLOGY

High efficacy of two artemisinin-based combinations (artemether-lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria

(2010) C. O. Falade et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Efficacy of oral single dose therapy with artemisinin–naphthoquine phosphate in uncomplicated falciparum malaria

(2009) Thein Tun et al.   ACTA TROPICA

Safety of artemisinins during early pregnancy, assessed in 62 Sudanese women

(2009) I. Adam et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Population Pharmacokinetics of Lumefantrine in Pregnant Women Treated with Artemether-Lumefantrine for Uncomplicated Plasmodium falciparum Malaria

(2009) J. Tarning et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A randomized, controlled trial of artemisinin-piperaquine vs dihydroartemisinin-piperaquine phosphate in treatment of falciparum malaria

(2009) Trieu Nguyen Trung et al.   Chinese Journal of Integrative Medicine

Azithromycin plus Artesunate versus Artemether‐Lumefantrine for Treatment of Uncomplicated Malaria in Tanzanian Children: A Randomized, Controlled Trial

(2009) Alma Sykes et al.   CLINICAL INFECTIOUS DISEASES

Artemether‐Lumefantrine versus Dihydroartemisinin‐Piperaquine for Falciparum Malaria: A Longitudinal, Randomized Trial in Young Ugandan Children

(2009) Emmanuel Arinaitwe et al.   CLINICAL INFECTIOUS DISEASES

Pharmacokinetics of Sulfadoxine and Pyrimethamine in Intermittent Preventive Treatment of Malaria in Pregnancy

(2009) M M Nyunt et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

New developments in Plasmodium vivax malaria: severe disease and the rise of chloroquine resistance

(2009) Ric N Price et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Discovery, mechanisms of action and combination therapy of artemisinin

(2009) Liwang Cui et al.   Expert Review of Anti-Infective Therapy

Early rectal artesunate administration: a life-saver in remote areas?

(2009) Martin P Grobusch   Future Microbiology

The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration

(2009) Alessandro Liberati et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Comparison of Sulfadoxine‐Pyrimethamine, Unsupervised Artemether‐Lumefantrine, and Unsupervised Artesunate‐Amodiaquine Fixed‐Dose Formulation for UncomplicatedPlasmodium falciparumMalaria in Benin: A Randomized Effectiveness Noninferiority Trial

(2009) Jean‐François Faucher et al.   JOURNAL OF INFECTIOUS DISEASES

Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children

(2009) Shereen Katrak et al.   MALARIA JOURNAL

Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi

(2009) David J Bell et al.   MALARIA JOURNAL

Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies

(2009) Maryline Bonnet et al.   MALARIA JOURNAL

A comparative, randomized clinical trial of artemisinin/naphtoquine twice daily one day versus artemether/lumefantrine six doses regimen in children and adults with uncomplicated falciparum malaria in Côte d'Ivoire

(2009) Offianan A Toure et al.   MALARIA JOURNAL

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacokinetic and Toxicological Profile of Artemisinin Compounds: An Update

(2009) Bikash Medhi et al.   PHARMACOLOGY

Randomized Trial of Artesunate+Amodiaquine, Sulfadoxine-Pyrimethamine+Amodiaquine, Chlorproguanal-Dapsone and SP for Malaria in Pregnancy in Tanzania

(2009) Theonest K. Mutabingwa et al.   PLoS One

Chlorproguanil−Dapsone−Artesunate versus Artemether−Lumefantrine: A Randomized, Double-Blind Phase III Trial in African Children and Adolescents with Uncomplicated Plasmodium falciparum Malaria

(2009) Zul Premji et al.   PLoS One

Dihydroartemisinin-Piperaquine and Artemether-Lumefantrine for Treating Uncomplicated Malaria in African Children: A Randomised, Non-Inferiority Trial

(2009) Quique Bassat et al.   PLoS One

Mefloquine neurotoxicity: A literature review

(2009) Stephen Toovey   Travel Medicine and Infectious Disease

Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count

(2008) Robert L. Clark et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Malaria Chemoprophylaxis: Strategies for Risk Groups

(2008) P. Schlagenhauf et al.   CLINICAL MICROBIOLOGY REVIEWS

Effects of artesunate-cotrimoxazole and amodiaquine-artesunate against asexual and sexual stages of Plasmodium falciparum malaria in Nigerian children

(2008) Fatai A. Fehintola et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial

(2008) Salim Abdulla et al.   LANCET

Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial

(2008) MF Gomes et al.   LANCET

A randomized trial on effectiveness of artemether-lumefantrine versus artesunate plus amodiaquine for unsupervised treatment of uncomplicated Plasmodium falciparum malaria in Ghanaian children

(2008) Robin Kobbe et al.   MALARIA JOURNAL

A randomized, open-label, comparative efficacy trial of artemether-lumefantrine suspension versus artemether-lumefantrine tablets for treatment of uncomplicated Plasmodium falciparum malaria in children in western Kenya

(2008) Elizabeth A Juma et al.   MALARIA JOURNAL

Evaluation of the efficacy and safety of artemether-lumefantrine in the treatment of acute uncomplicated Plasmodium falciparum malaria in Nigerian infants and children

(2008) Catherine O Falade et al.   MALARIA JOURNAL

Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children

(2008) Catherine Maiteki-Sebuguzi et al.   MALARIA JOURNAL

Amodiaquine-artesunate vs artemether-lumefantrine for uncomplicated malaria in Ghanaian children: a randomized efficacy and safety trial with one year follow-up

(2008) George O Adjei et al.   MALARIA JOURNAL

A randomized trial to monitor the efficacy and effectiveness by QT-NASBA of artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment and transmission control of uncomplicated Plasmodium falciparum malaria in western Kenya

(2008) Petra F Mens et al.   MALARIA JOURNAL

Assessment of the pharmacokinetics and dynamics of two combination regimens of fosmidomycin-clindamycin in patients with acute uncomplicated falciparum malaria

(2008) Ronnatrai Ruengweerayut et al.   MALARIA JOURNAL

A Trial of Combination Antimalarial Therapies in Children from Papua New Guinea

(2008) Harin A. Karunajeewa et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

(2008) Harald Noedl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treating Uncomplicated Malaria: A Randomized Trial to Guide Policy in Uganda

(2008) Adoke Yeka et al.   PLoS One

An Open Label, Randomised Trial of Artesunate+Amodiaquine, Artesunate+Chlorproguanil-Dapsone and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria

(2008) Seth Owusu-Agyei et al.   PLoS One

A randomized clinical trial comparing safety, clinical and parasitological response to artemether-lumefantrine and chlorproguanil-dapsone in treatment of uncomplicated malaria in pregnancy in Mulago hospital, Uganda

(2008) Daniel Kabonge Kaye et al.   Journal of Infection in Developing Countries

Preventing malaria in travellers

(2008) David G Lalloo et al.   BMJ-British Medical Journal

A Randomised Controlled Trial of Artemether-Lumefantrine Versus Artesunate for Uncomplicated Plasmodium falciparum Treatment in Pregnancy

(2008) Rose McGready et al.   PLOS MEDICINE

Plasmodium knowlesi Malaria in Humans Is Widely Distributed and Potentially Life Threatening

(2007) J. Cox-Singh et al.   CLINICAL INFECTIOUS DISEASES