Pharmacogenomics of pediatric acute lymphoblastic leukemia

Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia

(2009) M. Ansari et al.   BLOOD

Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study

(2009) K. Schmiegelow et al.   BLOOD

Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status

(2009) Gabriele Stocco et al.   Expert Opinion On Drug Safety

Genome-wide Interrogation of Germline Genetic Variation Associated With Treatment Response in Childhood Acute Lymphoblastic Leukemia

(2009) Jun J. Yang   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Childhood ALL Researchers Focus on High-Risk Patients

(2009) Mary Jane Friedrich   JNCI-Journal of the National Cancer Institute

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

(2009) Elaine Coustan-Smith et al.   LANCET ONCOLOGY

Polymorphisms of xenobiotic metabolizing enzymes and DNA repair genes and outcome in childhood acute lymphoblastic leukemia

(2009) Vanessa da Silva Silveira et al.   LEUKEMIA RESEARCH

Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

(2009) Ching-Hon Pui et al.   NEW ENGLAND JOURNAL OF MEDICINE

Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: Role of polymorphisms of genes involved in glucocorticoid response

(2009) Sara Marino et al.   PEDIATRIC BLOOD & CANCER

Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia

(2008) Deborah French et al.   BLOOD

A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group

(2008) D. French et al.   BLOOD

Pharmacogenetics of minimal residual disease response in children with B-precursor acute lymphoblastic leukemia: a report from the Children's Oncology Group

(2008) S. M. Davies et al.   BLOOD

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

(2008) J. J. Yang et al.   BLOOD

Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells

(2008) E. Hulleman et al.   BLOOD

Methotrexate Pharmacokinetics in Transgenic Mice with Liver-Specific Expression of Human Organic Anion-Transporting Polypeptide 1B1 (SLCO1B1)

(2008) E. van de Steeg et al.   DRUG METABOLISM AND DISPOSITION

CRHR1Polymorphisms Predict Bone Density in Survivors of Acute Lymphoblastic Leukemia

(2008) Terreia S. Jones et al.   JOURNAL OF CLINICAL ONCOLOGY

The SWI/SNF Chromatin-Remodeling Complex and Glucocorticoid Resistance in Acute Lymphoblastic Leukemia

(2008) Nicolas Pottier et al.   JNCI-Journal of the National Cancer Institute

Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study

(2008) K Schmiegelow et al.   LEUKEMIA

γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

(2008) Pedro J Real et al.   NATURE MEDICINE

Cancer Survivorship: A Pediatric Perspective

(2008) W. Landier et al.   ONCOLOGIST

Additional genetic risk factor for death in children with acute lymphoblastic leukemia: A common polymorphism of the MTHFR gene

(2008) Jacek J. Pietrzyk et al.   PEDIATRIC BLOOD & CANCER

Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia

(2008) Landry K. Kamdem et al.   Pharmacogenetics and Genomics

New Genetic Abnormalities and Treatment Response in Acute Lymphoblastic Leukemia

(2008) Jules P.P. Meijerink et al.   SEMINARS IN HEMATOLOGY

Pharmacogenetics in Acute Lymphoblastic Leukemia

(2008) Meyling H. Cheok et al.   SEMINARS IN HEMATOLOGY

DNA variants in the dihydrofolate reductase gene and outcome in childhood ALL

(2007) S. Dulucq et al.   BLOOD

Effect of race on vincristine-associated neurotoxicity in pediatric acute lymphoblastic leukemia patients

(2007) Jamie L. Renbarger et al.   PEDIATRIC BLOOD & CANCER