Melatonin uses in oncology: breast cancer prevention and reduction of the side effects of chemotherapy and radiation

Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials

(2013)   LANCET

The effect of MELatOnin on Depression, anxietY, cognitive function and sleep disturbances in patients with breast cancer. The MELODY trial: protocol for a randomised, placebo-controlled, double-blinded trial

(2012) Melissa Voigt Hansen et al.   BMJ Open

Tamoxifen metabolites as active inhibitors of aromatase in the treatment of breast cancer

(2011) Wenjie Jessie Lu et al.   BREAST CANCER RESEARCH AND TREATMENT

Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo

(2011) Vladimir N. Anisimov et al.   CELL CYCLE

Overview of preoperative radiochemotherapy in breast cancer: past or future?

(2011) Céline Bourgier et al.   Clinical & Translational Oncology

Basic Mechanisms Involved in the Anti-Cancer Effects of Melatonin

(2011) M. D. Mediavilla et al.   CURRENT MEDICINAL CHEMISTRY

Hormonal Mechanisms Underlying the Relationship Between Obesity and Breast Cancer

(2011) Claire M. Perks et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

The role of chemotherapy and targeted agents in patients with metastatic breast cancer

(2011) Stephen R.D. Johnston   EUROPEAN JOURNAL OF CANCER

Melatonin or l-tryptophan accelerates healing of gastroduodenal ulcers in patients treated with omeprazole

(2011) Krzysztof Celinski et al.   JOURNAL OF PINEAL RESEARCH

Circadian regulation of molecular, dietary, and metabolic signaling mechanisms of human breast cancer growth by the nocturnal melatonin signal and the consequences of its disruption by light at night

(2011) David E. Blask et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling

(2011) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

Novel melatonin-based therapies: potential advances in the treatment of major depression

(2011) Ian B Hickie et al.   LANCET

Preventive therapy for breast cancer: a consensus statement

(2011) Jack Cuzick et al.   LANCET ONCOLOGY

Global breast cancer seasonality

(2010) Eun-Young Oh et al.   BREAST CANCER RESEARCH AND TREATMENT

Declining melatonin levels and MT1 receptor expression in aging rats is associated with enhanced mammary tumor growth and decreased sensitivity to melatonin

(2010) Steven M. Hill et al.   BREAST CANCER RESEARCH AND TREATMENT

Urinary 6-Sulphatoxymelatonin Levels and Risk of Breast Cancer in Premenopausal Women: The ORDET Cohort

(2010) E. S. Schernhammer et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Oral Contraceptive Use and Breast Cancer: A Prospective Study of Young Women

(2010) D. J. Hunter et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 Trial: Preventing Breast Cancer

(2010) V. G. Vogel et al.   Cancer Prevention Research

Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFκB/HIF-1α activation

(2010) Ruben R. Gonzalez-Perez et al.   CELLULAR SIGNALLING

In Vivo Inhibition of the Estrogen Sulfatase Enzyme and Growth of DMBA-Induced Mammary Tumors by Melatonin

(2010) A. Gonzalez et al.   CURRENT CANCER DRUG TARGETS

Clinical Uses of Melatonin: Evaluation of Human Trials

(2010) E.J. Sanchez-Barcelo et al.   CURRENT MEDICINAL CHEMISTRY

Blue light from light-emitting diodes elicits a dose-dependent suppression of melatonin in humans

(2010) Kathleen E. West et al.   JOURNAL OF APPLIED PHYSIOLOGY

Arzoxifene for prevention of fractures and invasive breast cancer in postmenopausal women

(2010) Steven R Cummings et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome

(2010) Marzena Koziróg et al.   JOURNAL OF PINEAL RESEARCH

Lasofoxifene in Postmenopausal Women with Osteoporosis

(2010) Steven R. Cummings et al.   NEW ENGLAND JOURNAL OF MEDICINE

Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity

(2010) D.-X. Tan et al.   Obesity Reviews

Improvement of Capecitabine Antitumoral Activity by Melatonin in Pancreatic Cancer

(2010) Juan Ruiz-Rabelo et al.   PANCREAS

Melatonin—A pleiotropic, orchestrating regulator molecule

(2010) Rüdiger Hardeland et al.   PROGRESS IN NEUROBIOLOGY

Melatonin inhibits mitogenic cross-talk between retinoic acid-related orphan receptor alpha (RORα) and ERα in MCF-7 human breast cancer cells

(2010) Chunmin Dong et al.   STEROIDS

Melatonin inhibits aromatase promoter expression by regulating cyclooxygenases expression and activity in breast cancer cells

(2009) C Martínez-Campa et al.   BRITISH JOURNAL OF CANCER

Melatonin Stimulates the Release of Gonadotropin-Inhibitory Hormone by the Avian Hypothalamus

(2009) Vishwajit S. Chowdhury et al.   ENDOCRINOLOGY

Repeated measures of serum glucose and insulin in relation to postmenopausal breast cancer

(2009) Geoffrey C. Kabat et al.   INTERNATIONAL JOURNAL OF CANCER

Identification of Human GnIH Homologs, RFRP-1 and RFRP-3, and the Cognate Receptor, GPR147 in the Human Hypothalamic Pituitary Axis

(2009) Takayoshi Ubuka et al.   PLoS One

Patterns of circadian activity rhythms and their relationships with fatigue and anxiety/depression in women treated with breast cancer adjuvant chemotherapy

(2009) Ann M. Berger et al.   SUPPORTIVE CARE IN CANCER

Melatonin as a Selective Estrogen Enzyme Modulator

(2008) S. Cos et al.   CURRENT CANCER DRUG TARGETS

Impact of antioxidant supplementation on chemotherapeutic toxicity: A systematic review of the evidence from randomized controlled trials

(2008) Keith I. Block et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of melatonin receptor (MT1) and interaction between melatonin and estrogen in endometrial cancer cell line

(2008) Mari Watanabe et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Selective estrogen enzyme modulator actions of melatonin in human breast cancer cells

(2008) A. Gonzalez et al.   JOURNAL OF PINEAL RESEARCH

Should Supplemental Antioxidant Administration Be Avoided During Chemotherapy and Radiation Therapy?

(2008) B. D. Lawenda et al.   JNCI-Journal of the National Cancer Institute

The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats

(2008) J. Luo et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION