Targeting memory processes with drugs to prevent or cure PTSD

How We See Others: The Psychobiology of Schemas and Transference

(2016) Dan J. Stein   CNS SPECTRUMS

The Role of Genes in Defining a Molecular Biology of PTSD

(2013) Rachel Yehuda et al.   DISEASE MARKERS

Venlafaxine facilitates between-session extinction and prevents reinstatement of auditory-cue conditioned fear

(2012) Cheng-hao Yang et al.   BEHAVIOURAL BRAIN RESEARCH

Prescribing Trends in Veterans With Posttraumatic Stress Disorder

(2012) Nancy C. Bernardy et al.   JOURNAL OF CLINICAL PSYCHIATRY

Rethinking the Emotional Brain

(2012) Joseph LeDoux   NEURON

Combined Prolonged Exposure Therapy and Paroxetine for PTSD Related to the World Trade Center Attack: A Randomized Controlled Trial

(2011) Franklin R. Schneier et al.   AMERICAN JOURNAL OF PSYCHIATRY

Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

(2011) Mohammed R. Milad et al.   Annual Review of Psychology

Molecular Mechanisms of Fear Learning and Memory

(2011) Joshua P. Johansen et al.   CELL

Effect of Acute Posttrauma Propranolol on PTSD Outcome and Physiological Responses During Script-Driven Imagery

(2011) Elizabeth A. Hoge et al.   CNS Neuroscience & Therapeutics

Classification of trauma and stressor-related disorders in DSM-5

(2011) Matthew J. Friedman et al.   DEPRESSION AND ANXIETY

Noradrenergic enhancement of reconsolidation in the amygdala impairs extinction of conditioned fear in rats-a possible mechanism for the persistence of traumatic memories in PTSD

(2011) Jacek Dębiec et al.   DEPRESSION AND ANXIETY

New approaches to combining pharmacotherapy and psychotherapy for posttraumatic stress disorder

(2011) Laura C Pratchett et al.   EXPERT OPINION ON PHARMACOTHERAPY

Adjunctive Risperidone Treatment for Antidepressant-Resistant Symptoms of Chronic Military Service–Related PTSD

(2011) John H. Krystal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Eszopiclone for the Treatment of Posttraumatic Stress Disorder and Associated Insomnia

(2011) Mark H. Pollack et al.   JOURNAL OF CLINICAL PSYCHIATRY

Preliminary evidence of hippocampal damage in chronic users of ecstasy

(2011) Bjørnar den Hollander et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Pharmacological Interaction With the Sigma1 (σ1)-Receptor in the Acute Behavioral Effects of Antidepressants

(2011) Vanessa Villard et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

(2011) Kerry J. Ressler et al.   NATURE

Temporary disruption of fear-potentiated startle following PKMζ inhibition in the amygdala

(2011) Ryan G Parsons et al.   NATURE NEUROSCIENCE

Biomarkers of PTSD: Neuropeptides and immune signaling

(2011) Dewleen G. Baker et al.   NEUROPHARMACOLOGY

PTSD and gene variants: New pathways and new thinking

(2011) Kelly Skelton et al.   NEUROPHARMACOLOGY

Stimulation of the Noradrenergic System during Memory Formation Impairs Extinction Learning but not the Disruption of Reconsolidation

(2011) Marieke Soeter et al.   NEUROPSYCHOPHARMACOLOGY

SSRIs and conditioned fear

(2011) Takeshi Inoue et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Cortisol suppression by dexamethasone reduces exaggerated fear responses in posttraumatic stress disorder

(2011) Tanja Jovanovic et al.   PSYCHONEUROENDOCRINOLOGY

Hydrocortisone suppression of the fear-potentiated startle response and posttraumatic stress disorder

(2011) Mark W. Miller et al.   PSYCHONEUROENDOCRINOLOGY

Fear Erasure in Mice Requires Synergy Between Antidepressant Drugs and Extinction Training

(2011) N. N. Karpova et al.   SCIENCE

Psychobiological allostasis: resistance, resilience and vulnerability

(2011) Ilia N. Karatsoreos et al.   TRENDS IN COGNITIVE SCIENCES

How the Neurocircuitry and Genetics of Fear Inhibition May Inform Our Understanding of PTSD

(2010) Tanja Jovanovic et al.   AMERICAN JOURNAL OF PSYCHIATRY

Evidence-based treatments for PTSD, new directions, and special challenges

(2010) Judith Cukor et al.   Annals of the New York Academy of Sciences

A role for α₁-adrenergic receptors in extinction of conditioned fear and cocaine conditioned place preference.

(2010) Rick E. Bernardi et al.   BEHAVIORAL NEUROSCIENCE

Sidman Instrumental Avoidance Initially Depends on Lateral and Basal Amygdala and Is Constrained by Central Amygdala-Mediated Pavlovian Processes

(2010) Gabriel Lázaro-Muñoz et al.   BIOLOGICAL PSYCHIATRY

Considering PTSD for DSM-5

(2010) Matthew J. Friedman et al.   DEPRESSION AND ANXIETY

Impaired fear inhibition is a biomarker of PTSD but not depression

(2010) Tanja Jovanovic et al.   DEPRESSION AND ANXIETY

A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trial

(2010) Sanjay J. Mathew et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Prazosin Versus Quetiapine for Nighttime Posttraumatic Stress Disorder Symptoms in Veterans

(2010) Melanie G. Byers et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Continuing the search for the engram: examining the mechanism of fear memories

(2010) Sheena Josselyn   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

The safety and efficacy of ±3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study

(2010) Michael C Mithoefer et al.   JOURNAL OF PSYCHOPHARMACOLOGY

How does PKMζ maintain long-term memory?

(2010) Todd C. Sacktor   NATURE REVIEWS NEUROSCIENCE

Morphine Use after Combat Injury in Iraq and Post-Traumatic Stress Disorder

(2010) Troy Lisa Holbrook et al.   NEW ENGLAND JOURNAL OF MEDICINE

Therapeutic utility of non-peptidic CRF1 receptor antagonists in anxiety, depression, and stress-related disorders: Evidence from animal models

(2010) John H. Kehne et al.   PHARMACOLOGY & THERAPEUTICS

Effects of Duloxetine in Treatment-Refractory Men with Posttraumatic Stress Disorder

(2010) E. Walderhaug et al.   PHARMACOPSYCHIATRY

Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear

(2010) Hans-Christian Pape et al.   PHYSIOLOGICAL REVIEWS

Fear and safety learning differentially affect synapse size and dendritic translation in the lateral amygdala

(2010) L. E. Ostroff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aripiprazole in the treatment of posttraumatic stress disorder: an open-label trial

(2010) Marcelo Feijo Mello et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Consequences of extinction training on associative and non-associative fear in a mouse model of Posttraumatic Stress Disorder (PTSD)

(2009) Yulia Golub et al.   BEHAVIOURAL BRAIN RESEARCH

Long-Lasting Incubation of Conditioned Fear in Rats

(2009) Charles L. Pickens et al.   BIOLOGICAL PSYCHIATRY

Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder

(2009) Mohammed R. Milad et al.   BIOLOGICAL PSYCHIATRY

Risk and resilience: Genetic and environmental influences on development of the stress response

(2009) Charles F. Gillespie et al.   DEPRESSION AND ANXIETY

Single prolonged stress: toward an animal model of posttraumatic stress disorder

(2009) Shigeto Yamamoto et al.   DEPRESSION AND ANXIETY

Preliminary Evidence for the Effects of Morphine on Posttraumatic Stress Disorder Symptoms in One- to Four-Year-Olds With Burns

(2009) Frederick J. Stoddard et al.   Journal of Burn Care & Research

Placebo-Controlled Trial of Risperidone Augmentation for Selective Serotonin Reuptake Inhibitor-Resistant Civilian Posttraumatic Stress Disorder

(2009) Barbara O. Rothbaum et al.   JOURNAL OF CLINICAL PSYCHIATRY

Divalproex in the Treatment of Posttraumatic Stress Disorder

(2009) Lori L. Davis et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Preliminary Findings Concerning the Use of Prazosin for the Treatment of Posttraumatic Nightmares in a Refugee Population

(2009) Lorin Boynton et al.   Journal of Psychiatric Practice

5-HT2A receptor antagonism by MDL 11,939 during inescapable stress prevents subsequent exaggeration of acoustic startle response and reduced body weight in rats

(2009) Xiaolong Jiang et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The impact of traumatic stressors in civilian occupational settings

(2009) Alexander C McFarlane et al.   JOURNAL OF PUBLIC HEALTH POLICY

Preventing the return of fear in humans using reconsolidation update mechanisms

(2009) Daniela Schiller et al.   NATURE

Beyond extinction: erasing human fear responses and preventing the return of fear

(2009) Merel Kindt et al.   NATURE NEUROSCIENCE

Stress, memory and the amygdala

(2009) Benno Roozendaal et al.   NATURE REVIEWS NEUROSCIENCE

Changing Fear: The Neurocircuitry of Emotion Regulation

(2009) Catherine A Hartley et al.   NEUROPSYCHOPHARMACOLOGY

Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and α1-adrenergic receptor

(2009) Nobukazu Kakui et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Posttraumatic stress disorder may be associated with impaired fear inhibition: Relation to symptom severity

(2009) Tanja Jovanovic et al.   PSYCHIATRY RESEARCH

A Study of the Protective Function of Acute Morphine Administration on Subsequent Posttraumatic Stress Disorder

(2008) Richard A. Bryant et al.   BIOLOGICAL PSYCHIATRY

Impaired Fear Extinction Learning and Cortico-Amygdala Circuit Abnormalities in a Common Genetic Mouse Strain

(2008) K. Hefner et al.   JOURNAL OF NEUROSCIENCE

Noradrenergic Signaling in Infralimbic Cortex Increases Cell Excitability and Strengthens Memory for Fear Extinction

(2008) D. Mueller et al.   JOURNAL OF NEUROSCIENCE

Ketamine aggravates symptoms of acute stress disorder in a naturalistic sample of accident victims

(2008) M. Schönenberg et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Amygdala intercalated neurons are required for expression of fear extinction

(2008) Ekaterina Likhtik et al.   NATURE

A modified single-prolonged stress model for post-traumatic stress disorder

(2008) Wen Wang et al.   NEUROSCIENCE LETTERS

The Correlation Between Ketamine and Posttraumatic Stress Disorder in Burned Service Members

(2008) Laura L. McGhee et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Prazosin Effects on Objective Sleep Measures and Clinical Symptoms in Civilian Trauma Posttraumatic Stress Disorder: A Placebo-Controlled Study

(2007) Fletcher B. Taylor et al.   BIOLOGICAL PSYCHIATRY

Effect of post-retrieval propranolol on psychophysiologic responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder

(2007) Alain Brunet et al.   JOURNAL OF PSYCHIATRIC RESEARCH