Utilization ofglutathione S-transferase Mu 1- andTheta 1-null mice as animal models for absorption, distribution, metabolism, excretion and toxicity studies

PHASE II DRUG METABOLIZING ENZYMES

(2012) Petra Jancova et al.   BIOMEDICAL PAPERS-OLOMOUC

Resistance to acetaminophen-induced hepatotoxicity in glutathione S-transferase Mu 1-null mice

(2012) Shingo Arakawa et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Knockout and transgenic mice in glutathione transferase research

(2011) Colin J. Henderson et al.   DRUG METABOLISM REVIEWS

Pharmacogenetics, Pharmacogenomics, and Individualized Medicine

(2011) Q. Ma et al.   PHARMACOLOGICAL REVIEWS

Humanizing π-Class Glutathione S-Transferase Regulation in a Mouse Model Alters Liver Toxicity in Response to Acetaminophen Overdose

(2011) Matthew P. Vaughn et al.   PLoS One

Transgenic Animal Models in Toxicology: Historical Perspectives and Future Outlook

(2011) Darrell R. Boverhof et al.   TOXICOLOGICAL SCIENCES

Pharmacogenomics in Drug Induced Liver Injury

(2010) Raul Andrade et al.   CURRENT DRUG METABOLISM

Methemoglobinemia Induced by 1,2-Dichloro-4-nitrobenzene in Mice with a Disrupted Glutathione S-Transferase Mu 1 Gene

(2010) S. Arakawa et al.   DRUG METABOLISM AND DISPOSITION

A Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent Glucuronidation

(2010) H. Cai et al.   DRUG METABOLISM AND DISPOSITION

Drug-Induced Idiosyncratic Hepatotoxicity: Prevention Strategy Developed after the Troglitazone Case

(2010) Toshihiko Ikeda   Drug Metabolism and Pharmacokinetics

Pharmacogenetics of drug-induced liver injury

(2010) Stefan Russmann et al.   HEPATOLOGY

Structural determinants in domain II of human glutathione transferase M2-2 govern the characteristic activities with aminochrome, 2-cyano-1, 3-dimethyl-1-nitrosoguanidine, and 1, 2-dichloro-4-nitrobenzene

(2009) Lars O. Hansson et al.   PROTEIN SCIENCE

Glutathione-S-transferase A3 knockout mice are sensitive to acute cytotoxic and genotoxic effects of aflatoxin B1

(2009) Zoran Ilic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Current Industrial Practices in Assessing CYP450 Enzyme Induction: Preclinical and Clinical

(2008) Michael Sinz et al.   AAPS Journal

Glutathione-S-transferase (GST) M1 null genotype and combined GSTM1 and GSTT1 null genotypes are risk factors for increased serum γ-glutamyltransferase in valproic acid-treated patients

(2008) Yumi Fukushima et al.   CLINICA CHIMICA ACTA

Structure, Function and Polymorphism of Human Cytosolic Sulfotransferases

(2008) Yong Li et al.   CURRENT DRUG METABOLISM

GlutathioneS-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury

(2008) M. Isabel Lucena et al.   HEPATOLOGY

Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response

(2007) Kohsuke Takeda et al.   Annual Review of Pharmacology and Toxicology