Metabolic considerations of drugs in the treatment of allergic diseases

A new perspective on muscarinic receptor antagonism in obstructive airways diseases

(2013) Herman Meurs et al.   CURRENT OPINION IN PHARMACOLOGY

Anti-Parkinson's disease drugs and pharmacogenetic considerations

(2013) José A G Agúndez et al.   Expert Opinion on Drug Metabolism & Toxicology

Small-airways dysfunction associates with respiratory symptoms and clinical features of asthma: A systematic review

(2013) Erica van der Wiel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Detection of main urinary metabolites of β2-agonists clenbuterol, salbutamol and terbutaline by liquid chromatography high resolution mass spectrometry

(2013) Juan C. Domínguez-Romero et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Fluticasone Propionate Pharmacogenetics: CYP3A4*22 Polymorphism and Pediatric Asthma Control

(2013) Chris Stockmann et al.   JOURNAL OF PEDIATRICS

Fluoxetine Inhibition of CYP3A4 Potentiating Adrenal Suppression and Peptic Ulcer Disease from Intra-Articular Triamcinolone Injections

(2013) Thorsten M. Leucker et al.   PAIN MEDICINE

Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the “Missing Heritability” Problem

(2013) Kathrin Klein et al.   Frontiers in Genetics

Effect of CYP3A4 inducer dexamethasone on hepatotoxicity of lapatinib: clinical and in vitro evidence

(2012) Yi Ling Teo et al.   BREAST CANCER RESEARCH AND TREATMENT

The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of inhaled fluticasone furoate and vilanterol trifenatate in healthy subjects

(2012) Rodger Kempsford et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified

(2012) Silke Redler et al.   EXPERIMENTAL DERMATOLOGY

Sulfation of ractopamine and salbutamol by the human cytosolic sulfotransferases

(2012) K. Ko et al.   JOURNAL OF BIOCHEMISTRY

Identification of microRNAs as a potential novel regulatory mechanism in HSD11B1 expression

(2012) Yanyan Han et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Rapid Onset of Iatrogenic Adrenal Insufficiency in a Patient with Cystic Fibrosis–Related Liver Disease Treated with Inhaled Corticosteroids and a Moderate CYP3A4 Inhibitor

(2011) Wynton C Hoover et al.   ANNALS OF PHARMACOTHERAPY

CYP2C8 but not CYP3A4 is important in the pharmacokinetics of montelukast

(2011) Tiina Karonen et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Evaluation of 6β-Hydroxycortisol, 6β-Hydroxycortisone, and a Combination of the Two as Endogenous Probes for Inhibition of CYP3A4 In Vivo

(2011) C-C Peng et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Updates on the use of inhaled corticosteroids in asthma

(2011) Stuart W. Stoloff et al.   Current Opinion in Allergy and Clinical Immunology

Reevaluation of the Microsomal Metabolism of Montelukast: Major Contribution by CYP2C8 at Clinically Relevant Concentrations

(2011) A. M. Filppula et al.   DRUG METABOLISM AND DISPOSITION

Pharmacokinetic evaluation of olopatadine for the treatment of allergic rhinitis and conjunctivitis

(2011) Andrew S Nickels et al.   Expert Opinion on Drug Metabolism & Toxicology

Mometasone furoate dry powder inhaler for the treatment of asthma

(2011) Tracy B Fausnight et al.   EXPERT OPINION ON PHARMACOTHERAPY

Histamine and H1-antihistamines: Celebrating a century of progress

(2011) F. Estelle R. Simons et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inhaled Fluticasone Causes Iatrogenic Cushing’s Syndrome in Patients Treated with Ritonavir

(2011) Keren Mahlab-Guri et al.   JOURNAL OF ASTHMA

Biochemical Basis of Asthma Therapy

(2011) Peter J. Barnes   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacokinetics of Oral Dexamethasone and Midazolam When Administered With Single-Dose Intravenous 150 mg Fosaprepitant in Healthy Adult Subjects

(2011) Thomas C. Marbury et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Airway Peroxidases Catalyze Nitration of the  2-Agonist Salbutamol and Decrease Its Pharmacological Activity

(2010) K. J. Reszka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Deflazacort

(2010) N Joshi et al.   Journal of Postgraduate Medicine

Triamcinolone Acetonide Induced Secondary Adrenal Insufficiency Related to Impaired CYP3A4 Metabolism by Coadministration of Nefazodone: Table 1

(2010) John B. Hagan et al.   PAIN MEDICINE

Efficacy and safety of ciclesonide in the treatment of 24,037 asthmatic patients in routine medical care

(2010) Claus F. Vogelmeier et al.   RESPIRATORY MEDICINE

Relationship between omalizumab pharmacokinetics, IgE pharmacodynamics and symptoms in patients with severe persistent allergic (IgE-mediated) asthma

(2009) Philip J. Lowe et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Gene dosage imbalances in patients with 46,XY gonadal DSD detected by an in-house-designed synthetic probe set for multiplex ligation-dependent probe amplification analysis

(2009) M Barbaro et al.   CLINICAL GENETICS

Terbutaline sulfoconjugate: characterization and urinary excretion monitored by LC/ESI-MS/MS

(2009) A. K. Orlovius et al.   Drug Testing and Analysis

Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: Is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?

(2009) José AG Agúndez et al.   Expert Opinion on Drug Metabolism & Toxicology

Dose dependency of brain histamine H1 receptor occupancy following oral administration of cetirizine hydrochloride measured using PET with [11C]doxepin

(2009) Manabu Tashiro et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Interaction of CYP2C8 and CYP2C9 genotypes modifies the risk for nonsteroidal anti-inflammatory drugs-related acute gastrointestinal bleeding

(2009) Gerardo Blanco et al.   Pharmacogenetics and Genomics

Histamine pharmacogenomics

(2009) Elena García-Martín et al.   PHARMACOGENOMICS

Unsuspected polymorphic metabolism of rupatadine via its primary metabolite, desloratadine

(2009) Nuggehally R Srinivas   Primary Care Respiratory Journal

Histamine H1-receptor blockade in humans affects psychomotor performance but not memory

(2008) P. van Ruitenbeek et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Human Δ4-3-oxosteroid 5β-reductase (AKR1D1) deficiency and steroid metabolism

(2008) Mario Palermo et al.   STEROIDS

Pharmacological profile, efficacy and safety of rupatadine in allergic rhinitis

(2008) Subodh Katiyar et al.   Primary Care Respiratory Journal