The contribution of oxidative stress to drug-induced organ toxicity and its detectionin vitroandin vivo

Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells

(2011) Xiaofang Huo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mitochondrial ROS production under cellular stress: comparison of different detection methods

(2011) Andrey V. Kuznetsov et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ratiometric Coumarin−Neutral Red (CONER) Nanoprobe for Detection of Hydroxyl Radicals

(2011) Gabriela M. Ganea et al.   ANALYTICAL CHEMISTRY

Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

(2011) Xiaoqiang Chen et al.   CHEMICAL SOCIETY REVIEWS

Mitochondrial glutathione transferases involving a new function for membrane permeability transition pore regulation

(2011) Yoko Aniya et al.   DRUG METABOLISM REVIEWS

Identification ofDrosophilaSOD3 and its protective role against phototoxic damage to cells

(2011) Inhee Jung et al.   FEBS LETTERS

Cyclophilin D deficiency prevents diet-induced obesity in mice

(2011) Kishor Devalaraja-Narashimha et al.   FEBS LETTERS

Nrf2 degron-fused reporter system: a new tool for specific evaluation of Nrf2 inducers

(2011) Yosuke Hirotsu et al.   GENES TO CELLS

Clinicopathological features of non-alcoholic fatty liver disease

(2011) Kazushi Sugimoto et al.   HEPATOLOGY RESEARCH

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3

(2011) Julieta Araujo et al.   HUMAN MOLECULAR GENETICS

Effect of mitochondrial dysfunction and oxidative stress on endogenous levels of coenzyme Q10 in human cells

(2011) Hsiu-Chuan Yen et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Dihydrolipoyl histidinate zinc complex, a new antioxidant, attenuates hepatic ischemia-reperfusion injury in rats

(2011) Takashi Masuda et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Redox proteomics and drug development

(2011) Angelo D'Alessandro et al.   Journal of Proteomics

Current issues with acetaminophen hepatotoxicity—A clinically relevant model to test the efficacy of natural products

(2011) Hartmut Jaeschke et al.   LIFE SCIENCES

Mitochondrial Pathology in Parkinson's Disease

(2011) Anthony H. V. Schapira   MOUNT SINAI JOURNAL OF MEDICINE

Proteomic Approaches in Understanding a Detected Relationship between Chemotherapy-Induced Nephrotoxicity and Cell Respiration in HK-2 Cells

(2011) Juliana Dinéia Perez et al.   NEPHRON PHYSIOLOGY

Detection of lipid peroxidation in frozen-thawed avian spermatozoa using C11-BODIPY581/591

(2011) Agnieszka Partyka et al.   THERIOGENOLOGY

Potent Method for the Simultaneous Determination of Glutathione and Hydrogen Peroxide in Mitochondrial Compartments of Apoptotic Cells with Microchip Electrophoresis-Laser Induced Fluorescence

(2010) Zhenzhen Chen et al.   ANALYTICAL CHEMISTRY

Macrophage Migration Inhibitory Factor Provides Cardioprotection During Ischemia/Reperfusion by Reducing Oxidative Stress

(2010) Kiyokazu Koga et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial longevity pathways

(2010) Anna Raffaello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Detection of Lipid Peroxidation-Induced DNA Adducts Caused by 4-Oxo-2(E)-nonenal and 4-Oxo-2(E)-hexenal in Human Autopsy Tissues

(2010) Pei-Hsin Chou et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Role of Oxidative Stress and Anti-Oxidant Treatment in Platinum-Induced Peripheral Neurotoxicity

(2010) V. A. Carozzi et al.   CURRENT CANCER DRUG TARGETS

Redox compartmentalization and cellular stress

(2010) D. P. Jones et al.   DIABETES OBESITY & METABOLISM

Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies

(2010) El-Sayed E. El-Awady et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The mitochondrial permeability transition from yeast to mammals

(2010) Luca Azzolin et al.   FEBS LETTERS

Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: Another inconvenient truth

(2010) Jacek Zielonka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury

(2010) Anup Ramachandran et al.   FREE RADICAL RESEARCH

ESR Detection of ROS Generated by TiO2 Coated with Fluoridated Apatite

(2010) Tomofumi Sawada et al.   JOURNAL OF DENTAL RESEARCH

Qo site of mitochondrial complex III is the source of increased superoxide after transient exposure to hydrogen peroxide

(2010) Helena M. Viola et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Oxidation of Plasma Cysteine/Cystine and GSH/GSSG Redox Potentials by Acetaminophen and Sulfur Amino Acid Insufficiency in Humans

(2010) Y. O. Mannery et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Nanopore Detection of 8-Oxo-7,8-dihydro-2′-deoxyguanosine in Immobilized Single-Stranded DNA via Adduct Formation to the DNA Damage Site

(2010) Anna E. P. Schibel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative metabolism, ROS and NO under oxygen deprivation

(2010) Olga Blokhina et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter

(2010) G. C. Van de Bittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nimesulide aggravates redox imbalance and calcium dependent mitochondrial permeability transition leading to dysfunction in vitro

(2010) Brijesh Kumar Singh et al.   TOXICOLOGY

Spatial monitoring of toxicity in HMOX-LacZ transgenic mice

(2010) Rachel Young et al.   TRANSGENIC RESEARCH

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

(2010) Robert B. Hamanaka et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitochondrial Glutathione, a Key Survival Antioxidant

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria-Penetrating Peptides: Sequence Effects and Model Cargo Transport

(2009) Lema F. Yousif et al.   CHEMBIOCHEM

Elucidation of the Molecular Mechanisms of a Salicylhydrazide Class of Compounds by Proteomic Analysis

(2009) Xuefei Cao et al.   CURRENT CANCER DRUG TARGETS

Mitochondrial-targeted fluorescent probes for reactive oxygen species

(2009) Bryan C Dickinson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Mitochondrial-Targeted Antioxidants and Oxidative Stress: A Proteomic Prospective Study

(2009) Milagros Rocha et al.   CURRENT PHARMACEUTICAL DESIGN

Missense polymorphisms in three oxidative-stress enzymes (GSTP1, SOD2, and GPX1) and dyskinesias in Russian psychiatric inpatients from Siberia

(2009) A. F. Y. Al Hadithy et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma

(2009) Mee-Kyung Cha et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mitochondria: From basic biology to cardiovascular disease

(2009) Elizabeth Murphy et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Structure of Human Extracellular Copper–Zinc Superoxide Dismutase at 1.7 Å Resolution: Insights into Heparin and Collagen Binding

(2009) Svetlana V. Antonyuk et al.   JOURNAL OF MOLECULAR BIOLOGY

Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy

(2009) James J Kohler et al.   LABORATORY INVESTIGATION

SOD1-Targeted Gene Disruption in the Ericoid Mycorrhizal FungusOidiodendron maiusReduces Conidiation and the Capacity for Mycorrhization

(2009) S. Abbà et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets

(2008) Vilma A. Sardão et al.   CELL BIOLOGY AND TOXICOLOGY

The heterozygous Sod2+/− mouse: modeling the mitochondrial role in drug toxicity

(2008) Urs A. Boelsterli et al.   DRUG DISCOVERY TODAY

Quantitative Analysis of Redox-Sensitive Proteome with DIGE and ICAT

(2008) Cexiong Fu et al.   JOURNAL OF PROTEOME RESEARCH

Taxol induces oxidative neuronal cell death by enhancing the activity of NADPH oxidase in mouse cortical cultures

(2008) Hong Jeon Jang et al.   NEUROSCIENCE LETTERS

p21-LacZ reporter mice reflect p53-dependent toxic insult

(2008) Douglas B. Vasey et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress

(2007) Viviana I. Pérez et al.   FREE RADICAL BIOLOGY AND MEDICINE