CYP2C metabolism of oral antidiabetic drugs - impact on pharmacokinetics, drug interactions and pharmacogenetic aspects
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Title
CYP2C metabolism of oral antidiabetic drugs - impact on pharmacokinetics, drug interactions and pharmacogenetic aspects
Authors
Keywords
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Journal
Expert Opinion on Drug Metabolism & Toxicology
Volume 8, Issue 12, Pages 1549-1563
Publisher
Informa Healthcare
Online
2012-11-16
DOI
10.1517/17425255.2012.722619
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Note: Only part of the references are listed.- Correction: Comparative Effectiveness and Safety of Medications for Type 2 Diabetes
- (2013) Wendy L. Bennett et al. ANNALS OF INTERNAL MEDICINE
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- (2012) Sarah L Anderson et al. ANNALS OF PHARMACOTHERAPY
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- Pioglitazone and risk of bladder cancer among diabetic patients in France: a population-based cohort study
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- (2012) Joseph McGraw et al. Expert Opinion on Drug Metabolism & Toxicology
- TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial
- (2012) Charles F Burant et al. LANCET
- Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications
- (2012) Aleksi Tornio et al. TRENDS IN PHARMACOLOGICAL SCIENCES
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- (2011) Sherwyn L. Schwartz American Journal Geriatric Pharmacotherapy
- Impact of genetic polymorphisms of cytochrome P450 2 C (CYP2C) enzymes on the drug metabolism and design of antidiabetics
- (2011) Hao Sun et al. CHEMICO-BIOLOGICAL INTERACTIONS
- The Molecular Genetics of Sulfonylurea Receptors in the Pathogenesis and Treatment of Insulin Secretory Disorders and Type 2 Diabetes
- (2011) Veronica Lang et al. Current Diabetes Reports
- Efficacy and tolerability of sitagliptin monotherapy in elderly patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial
- (2011) Nir Barzilai et al. CURRENT MEDICAL RESEARCH AND OPINION
- Variations in tissue selectivity amongst insulin secretagogues: a systematic review
- (2011) A. S. Abdelmoneim et al. DIABETES OBESITY & METABOLISM
- Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus
- (2011) S. Kasichayanula et al. DIABETES OBESITY & METABOLISM
- Dose-Dependent Interaction between Gemfibrozil and Repaglinide in Humans: Strong Inhibition of CYP2C8 with Subtherapeutic Gemfibrozil Doses
- (2011) J. Honkalammi et al. DRUG METABOLISM AND DISPOSITION
- Mortality and cardiovascular risk associated with different insulin secretagogues compared with metformin in type 2 diabetes, with or without a previous myocardial infarction: a nationwide study
- (2011) Tina Ken Schramm et al. EUROPEAN HEART JOURNAL
- Mild hypoglycaemic attacks induced by sulphonylureas related to CYP2C9, CYP2C19 and CYP2C8 polymorphisms in routine clinical setting
- (2011) Osman Gökalp et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Impact of clinical factors and CYP2C9 variants for the risk of severe sulfonylurea-induced hypoglycemia
- (2011) Andreas Holstein et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Influence of CYP2C9 gene polymorphisms on response to glibenclamide in type 2 diabetes mellitus patients
- (2011) A. Surendiran et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Evaluation of the pharmacokinetic interaction after multiple oral doses of linagliptin and digoxin in healthy volunteers
- (2011) C. Friedrich et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Cytochrome P450-mediated cardiovascular drug interactions
- (2011) André J Scheen Expert Opinion on Drug Metabolism & Toxicology
- Sulfonylureas: do we need to introspect safety again?
- (2011) Devindra Sehra et al. Expert Opinion On Drug Safety
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- (2011) Daniel S. Budnitz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective
- (2011) Vangelis G Manolopoulos et al. PHARMACOGENOMICS
- Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake
- (2011) M. Niemi et al. PHARMACOLOGICAL REVIEWS
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- (2010) Annikka Kalliokoski et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Anti-Infectives and the Risk of Severe Hypoglycemia in Users of Glipizide or Glyburide
- (2010) H Schelleman et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Comparison of two sulfonylureas with high and low myocardial KATP channel affinity on myocardial infarct size and metabolism in a rat model of type 2 diabetes
- (2010) S. B. Kristiansen et al. DIABETOLOGIA
- Severe Hypoglycaemia Leading to Hospital Admission in Type 2 Diabetic Patients Aged 80 Years or Older
- (2010) D. Greco et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
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- (2010) Andreas Holstein et al. Expert Opinion On Drug Safety
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- (2010) H. Shao et al. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
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- (2010) T. Tirkkonen et al. JOURNAL OF INTERNAL MEDICINE
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- (2010) Yael Dinur Schejter et al. Journal of the American Medical Directors Association
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