Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicity

Role of oxidative stress in alcohol-induced liver injury

(2009) Arthur I. Cederbaum et al.   ARCHIVES OF TOXICOLOGY

Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function

(2009) F. Dutheil et al.   DRUG METABOLISM AND DISPOSITION

Human liver mitochondrial cytochrome P450 2D6 - individual variations and implications in drug metabolism

(2009) Michelle Cook Sangar et al.   FEBS Journal

Mitochondrial Targeting of Cytochrome P450 Proteins Containing NH2-terminal Chimeric Signals Involves an Unusual TOM20/TOM22 Bypass Mechanism

(2009) Hindupur K. Anandatheerthavarada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual Targeting of Nfs1 and Discovery of Its Novel Processing Enzyme, Icp55

(2009) Adi Naamati et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of genetic variants of human cytochrome P450 2D6 with impaired mitochondrial targeting

(2009) Michelle Cook Sangar et al.   MOLECULAR GENETICS AND METABOLISM

Function of Mitochondrial Stat3 in Cellular Respiration

(2009) J. Wegrzyn et al.   SCIENCE

Intracellular transport and localization of microsomal cytochrome P450

(2008) Etienne P. A. Neve et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Attenuation of doxorubicin-induced cardiac injury by mitochondrial glutaredoxin 2

(2008) Nicole M. Diotte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Multiple pathways for sorting mitochondrial precursor proteins

(2008) Natalia Bolender et al.   EMBO REPORTS

Influence of protein–protein interactions on the cellular localization of cytochrome P450

(2008) Elzbieta Szczesna-Skorupa et al.   Expert Opinion on Drug Metabolism & Toxicology

Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain

(2008) Latha Devi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model

(2008) Angelica Butura et al.   JOURNAL OF HEPATOLOGY

Bimodal Protein Targeting through Activation of Cryptic Mitochondrial Targeting Signals by an Inducible Cytosolic Endoprotease

(2008) Ettickan Boopathi et al.   MOLECULAR CELL

Knock-In Mouse Lines Expressing either Mitochondrial or Microsomal CYP1A1: Differing Responses to Dietary Benzo[a]pyrene as Proof of Principle

(2008) H. Dong et al.   MOLECULAR PHARMACOLOGY

CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells

(2008) Andres A. Caro et al.   TOXICOLOGY

Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?

(2008) Roberto Scatena et al.   PPAR Research

Cytochrome P450 and Chemical Toxicology

(2007) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY