Online electrochemistry/mass spectrometry in drug metabolism studies: principles and applications

Functional electrospray emitters

(2009) Michel Prudent et al.   ANALYST

Electrochemistry meets enzymes: instrumental on-line simulation of oxidative and conjugative metabolism reactions of toremifene

(2009) Wiebke Lohmann et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

On-Line Electrochemistry/Electrospray Ionization Mass Spectrometry (EC/ESI-MS) for the Generation and Identification of Nucleotide Oxidation Products

(2009) Anne Baumann et al.   ELECTROANALYSIS

Sensitivity of positive ion mode electrospray ionization mass spectrometry (ESI MS) in the analysis of purine bases in ESI MS and on-line electrochemistry ESI MS (EC/ESI MS)

(2009) Nare Alpheus Mautjana et al.   ELECTROCHIMICA ACTA

Liver tissue engineering in the evaluation of drug safety

(2009) Ajit Dash et al.   Expert Opinion on Drug Metabolism & Toxicology

Computational approaches to predict drug metabolism

(2009) Paul Czodrowski et al.   Expert Opinion on Drug Metabolism & Toxicology

Metabolic studies of tetrazepam based on electrochemical simulation in comparison to in vivo and in vitro methods

(2009) Anne Baumann et al.   JOURNAL OF CHROMATOGRAPHY A

Production of a reactive metabolite of troglitazone by electrochemical oxidation performed in nonaqueous medium

(2009) Kayoko Tahara et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A microfluidic chip for electrochemical conversions in drug metabolism studies

(2009) M. Odijk et al.   LAB ON A CHIP

Lessons from 60 years of pharmaceutical innovation

(2009) Bernard Munos   NATURE REVIEWS DRUG DISCOVERY

Electrochemically initiated tagging of thiols using an electrospray ionization based liquid microjunction surface sampling probe two-electrode cell

(2009) Gary J. Van Berkel et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Rapid detection and characterization of reactive drug metabolitesin vitrousing several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry

(2009) Timo Rousu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Quantification of Electrochemically Generated Iodine-Containing Metabolites Using Inductively Coupled Plasma Mass Spectrometry

(2008) Wiebke Lohmann et al.   ANALYTICAL CHEMISTRY

On-line Liquid Chromatography and Circular Dichroism Detection of Stereo-isomers of α-Tocopherol Derivatives Generated by an Electrochemical Reaction

(2008) Kayoko TAHARA et al.   ANALYTICAL SCIENCES

Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds

(2008) Elizabeth Anne Hillard et al.   CHEMICAL COMMUNICATIONS

Electrochemical Generation of Electrophilic Drug Metabolites: Characterization of Amodiaquine Quinoneimine and Cysteinyl Conjugates by MS, IR, and NMR

(2008) Ulrik Jurva et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Bioactivation of Diclofenacin Vitroandin Vivo: Correlation to Electrochemical Studies

(2008) Kim G. Madsen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Electrochemical Oxidation of Troglitazone: Identification and Characterization of the Major Reactive Metabolite in Liver Microsomes

(2008) Kim G. Madsen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

In Vitro Screening Techniques for Reactive Metabolites for Minimizing Bioactivation Potential in Drug Discovery

(2008) Chandra Prakash et al.   CURRENT DRUG METABOLISM

In Silico Prediction of Drug Properties

(2008) M. Hutter   CURRENT MEDICINAL CHEMISTRY

Novel Metabolites of Amodiaquine Formed by CYP1A1 and CYP1B1: Structure Elucidation Using Electrochemistry, Mass Spectrometry, and NMR

(2008) T. Johansson et al.   DRUG METABOLISM AND DISPOSITION

One-Electron Oxidation and Sensitivity of Uric Acid in On-Line Electrochemistry and in Electrospray Ionization Mass Spectrometry

(2008) Nare Alpheus Mautjana et al.   ELECTROANALYSIS

Antioxidant Pathways and One-Electron Oxidation of Dopamine and Cysteine in Electrospray and On-Line Electrochemistry Electrospray Ionization Mass Spectrometry

(2008) Nare Alpheus Mautjana et al.   ELECTROANALYSIS

Use of an Electrochemically Synthesised Metabolite of a Selective Androgen Receptor Modulator for Mass Spectrometry-Based Sports Drug Testing

(2008) Mario Thevis et al.   EUROPEAN JOURNAL OF MASS SPECTROMETRY

The use of inductively coupled plasma mass spectrometry as a detector in drug metabolism studies

(2008) Bente Gammelgaard et al.   Expert Opinion on Drug Metabolism & Toxicology

On-line electrochemistry/liquid chromatography/mass spectrometry for the simulation of pesticide metabolism

(2008) Wiebke Lohmann et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Electrochemical mass spectrometric studies on 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine

(2008) Neal Castagnoli et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Cytochrome P450 and Chemical Toxicology

(2007) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY